Surveillance of bloodstream infections in pediatric cancer centers - what have we learned and how do we move on?

Simon, Arne; Furtwängler, Rhoikos; Graf, Norbert; Laws, Hans Jürgen; Voigt, Sebastian; Piening, Brar; Geffers, Christine; Agyeman, Philipp; Ammann, Roland (2016). Surveillance of bloodstream infections in pediatric cancer centers - what have we learned and how do we move on? GMS hygiene and infection control, 11, Doc11. German Medical Science 10.3205/dgkh000271

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Pediatric patients receiving conventional chemotherapy for malignant disease face an increased risk of bloodstream infection (BSI). Since BSI may represent an acute life-threatening event in patients with profound immunosuppression, and show further negative impact on quality of life and anticancer treatment, the prevention of BSI is of paramount importance to improve and guarantee patients' safety during intensive treatment. The great majority of all pediatric cancer patients (about 85%) have a long-term central venous access catheter in use (type Broviac or Port; CVAD). Referring to the current surveillance definitions a significant proportion of all BSI in pediatric patients with febrile neutropenia is categorized as CVAD-associated BSI. This state of the art review summarizes the epidemiology and the distinct pathogen profile of BSI in pediatric cancer patients from the perspective of infection surveillance. Problems in executing the current surveillance definition in this patient population are discussed and a new concept for the surveillance of BSI in pediatric cancer patients is outlined.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine > Paediatric Haematology/Oncology

UniBE Contributor:

Agyeman, Philipp and Ammann, Roland

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2196-5226

Publisher:

German Medical Science

Language:

English

Submitter:

André Schaller

Date Deposited:

29 Mar 2017 13:06

Last Modified:

02 Apr 2017 02:18

Publisher DOI:

10.3205/dgkh000271

PubMed ID:

27274442

Uncontrolled Keywords:

Broviac; Port; bloodstream infection; pediatric oncology; surveillance

BORIS DOI:

10.7892/boris.93306

URI:

https://boris.unibe.ch/id/eprint/93306

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