Uter, Wolfgang; Warburton, Katharine; Weisshaar, Elke; Simon, Dagmar; Ballmer-Weber, Barbara; Mahler, Vera; Fuchs, Thomas; Geier, Johannes; Wilkinson, Mark (2016). Patch test results with rubber series in the European Surveillance System on Contact Allergies (ESSCA), 2013/14. Contact dermatitis, 75(6), pp. 345-352. Wiley-Blackwell 10.1111/cod.12651
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BACKGROUND
Contact allergy to rubber additives is common, particularly in patients with occupational dermatitis.
OBJECTIVES
To descriptively analyse and compare patch test reactions in patients patch tested both with the baseline series and with an additional 'rubber series' as used in the department.
METHODS
Patch test data from those members of the European Surveillance System on Contact Allergies (ESSCA) network (www.essca-dc.org) who also contributed data on rubber series patch test results were retrospectively analysed.
RESULTS
Among 29 522 patients patch tested, 2870 were eligible, that is, patch tested both with the baseline series and with a special rubber series. Of these, 8.8% had positive reaction(s) to one of the baseline screening rubber allergens (as compared with 4.2% in all patients), most often to carba mix, 12.3% had positive reaction(s) to allergens from an additional rubber series, and 6.4% had positive reaction(s) to both.
CONCLUSIONS
Additional testing with a dedicated rubber series, containing break-down single ingredients of mixes from the baseline series and additional rubber allergens, is warranted in patients with suspected contact allergy to rubber, to avoid false-negative results.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology |
UniBE Contributor: |
Simon, Dagmar |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0105-1873 |
Publisher: |
Wiley-Blackwell |
Language: |
English |
Submitter: |
Andrea Studer-Gauch |
Date Deposited: |
14 Feb 2017 11:15 |
Last Modified: |
05 Dec 2022 15:01 |
Publisher DOI: |
10.1111/cod.12651 |
PubMed ID: |
27402420 |
Uncontrolled Keywords: |
clinical epidemiology contact sensitization patch test rubber chemicals |
BORIS DOI: |
10.7892/boris.93477 |
URI: |
https://boris.unibe.ch/id/eprint/93477 |
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