Patch test results with rubber series in the European Surveillance System on Contact Allergies (ESSCA), 2013/14.

Uter, Wolfgang; Warburton, Katharine; Weisshaar, Elke; Simon, Dagmar; Ballmer-Weber, Barbara; Mahler, Vera; Fuchs, Thomas; Geier, Johannes; Wilkinson, Mark (2016). Patch test results with rubber series in the European Surveillance System on Contact Allergies (ESSCA), 2013/14. Contact dermatitis, 75(6), pp. 345-352. Wiley-Blackwell 10.1111/cod.12651

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BACKGROUND Contact allergy to rubber additives is common, particularly in patients with occupational dermatitis. OBJECTIVES To descriptively analyse and compare patch test reactions in patients patch tested both with the baseline series and with an additional 'rubber series' as used in the department. METHODS Patch test data from those members of the European Surveillance System on Contact Allergies (ESSCA) network (www.essca-dc.org) who also contributed data on rubber series patch test results were retrospectively analysed. RESULTS Among 29 522 patients patch tested, 2870 were eligible, that is, patch tested both with the baseline series and with a special rubber series. Of these, 8.8% had positive reaction(s) to one of the baseline screening rubber allergens (as compared with 4.2% in all patients), most often to carba mix, 12.3% had positive reaction(s) to allergens from an additional rubber series, and 6.4% had positive reaction(s) to both. CONCLUSIONS Additional testing with a dedicated rubber series, containing break-down single ingredients of mixes from the baseline series and additional rubber allergens, is warranted in patients with suspected contact allergy to rubber, to avoid false-negative results.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology

UniBE Contributor:

Simon, Dagmar

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0105-1873

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Sandra Nyffenegger

Date Deposited:

14 Feb 2017 11:15

Last Modified:

14 Feb 2017 11:15

Publisher DOI:

10.1111/cod.12651

PubMed ID:

27402420

Uncontrolled Keywords:

clinical epidemiology contact sensitization patch test rubber chemicals

BORIS DOI:

10.7892/boris.93477

URI:

https://boris.unibe.ch/id/eprint/93477

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