A European survey of perendoscopic treatment of biliary complications in patients with alveolar echinococcosis.

Ambregna, Sylvain; Koch, Stéphane; Sulz, Michael C; Grüner, Beate; Öztürk, Sümeyra; Chevaux, Jean-Baptiste; Sulima, Małgorzata; De Gottardi, Andrea; Napoléon, Bertrand; Abergel, Armand; Bichard, Philippe; Boytchev, Isabelle; Deprez, Pierre; Dumortier, Jerome; Frossard, Jean-Louis; Kull, Eric; Meny, Bernard; Moradpour, Darius; Prat, Fréderic; Vanbiervliet, Geoffroy; ... (2017). A European survey of perendoscopic treatment of biliary complications in patients with alveolar echinococcosis. Expert review of anti-infective therapy, 15(1), pp. 79-88. Expert Reviews 10.1080/14787210.2017.1252260

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BACKGROUND Biliary complications represent a turning point in the course of Alveolar Echinococcosis (AE). We conducted a European survey to collect data on the current usage and results of perendoscopic interventions (PEIs) for their treatment. METHODS Patient's characteristics and follow-up until January 31st, 2015 were recorded using an online questionnaire. RESULTS From 18 centers 129 PEIs were analyzed in 38 patients; 139 plastic stents were inserted during 85 PEIs; median time between stent placements was significantly longer when 3 stents or more were placed. Initial symptoms disappeared in 95% and long-term bile duct patency was obtained in 73% of cases. Cholangitis was a more frequent complication of the PEIs (10%) than in other indications; intensive lavage of the bile ducts may prevent this complication. CONCLUSION European centers use perendoscopic biliary drainage as an efficient and safe alternative to surgery to treat AE biliary complications. Insertion of multiple plastic stents delays stent occlusion and leads to effective and prolonged bile duct patency.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology

UniBE Contributor:

De Gottardi, Andrea

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1478-7210

Publisher:

Expert Reviews

Language:

English

Submitter:

Lilian Karin Smith-Wirth

Date Deposited:

17 Jul 2017 13:30

Last Modified:

17 Jul 2017 13:30

Publisher DOI:

10.1080/14787210.2017.1252260

PubMed ID:

27788612

Uncontrolled Keywords:

Echinococcus multilocularis; Endoscopic retrograde cholangio-pancreatography (ERCP); alveolar echinococcosis (AE); biliary stent; biliary stricture; cholangitis

URI:

https://boris.unibe.ch/id/eprint/93570

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