Diagnostik und Therapie myelodysplastischer Syndrome

Bonadies, Nicolas; Rüfer, Axel (2016). Diagnostik und Therapie myelodysplastischer Syndrome. Schweizer Zeitschrift für Onkologie(4), pp. 28-36. Rosenfluh Publikationen AG

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Diagnosis and treatment of myelodysplastic syndromes The myelodysplastic syndromes (MDS) are heterogeneous clonal disorders of the hematopoietic stem cells and affect mainly elderly people from the 7th decade of life. Management of MDS patients is challenging due to the broad spectrum of presentations and courses of the disease, varying from chronic cytopenia to rapid progression towards acute myeloid leukaemia (AML). The incidence and prevalence of MDS is expected to increase due to ageing of the population. Therefore, MDS is assumed to become one of the most important haematologic malignancies with an emerging impact on future healthcare costs. The only curative treatment is an allogeneic hematopoietic stem cell transplantation for which only a minority of patients is eligible. This review shall provide an update for practicing hemato-oncologists on the current understanding of pathophysiology as well as the recommendations for diagnosis and treatment of this emerging disease.

Item Type:

Journal Article (Review Article)


04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Haematology and Central Haematological Laboratory
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Unit Childrens Hospital > Forschungsgruppe Hämatologie (Erwachsene)

UniBE Contributor:

Bonadies, Nicolas


600 Technology > 610 Medicine & health




Rosenfluh Publikationen AG




Katrin Kölliker-Schütz

Date Deposited:

11 Apr 2017 09:17

Last Modified:

11 Apr 2017 09:17

Uncontrolled Keywords:

Myelodysplastic Syndromes, Treatment, Diagnosis / Bonadies Nicolas





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