A single session of prefrontal cortex transcranial direct current stimulation does not modulate implicit task sequence learning and consolidation

Savic, Branislav; Müri, René; Meier, Beat (2017). A single session of prefrontal cortex transcranial direct current stimulation does not modulate implicit task sequence learning and consolidation. Brain stimulation, 10(3), pp. 567-575. Elsevier 10.1016/j.brs.2017.01.001

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BACKGROUND: Transcranial direct current stimulation (tDCS) is assumed to affect cortical excitability and dependent on the specific stimulation conditions either to increase or decrease learning. OBJECTIVE: The purpose of this study was to modulate implicit task sequence learning with tDCS. METHODS: As cortico-striatal loops are critically involved in implicit task sequence learning, tDCS was applied above the dorsolateral prefrontal cortex (DLPFC). In Experiment 1, anodal, cathodal, or sham tDCS was applied before the start of the sequence learning task. In Experiment 2, stimulation was applied during the sequence learning task. Consolidation of learning was assessed after 24 h. RESULTS: The results of both experiments showed that implicit task sequence learning occurred consistently but it was not modulated by different tDCS conditions. Similarly, consolidation measured after a 24 h-interval including sleep was also not affected by stimulation. CONCLUSIONS: These results indicate that a single session of DLPFC tDCS is not sufficient to modulate implicit task sequence learning. This study adds to the accumulating evidence that tDCS may not be as effective as originally thought.

Item Type:

Journal Article (Original Article)

Division/Institute:

07 Faculty of Human Sciences > Institute of Psychology > Experimental Psychology and Neuropsychology
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

Savic, Branislav; Müri, René Martin and Meier, Beat

Subjects:

100 Philosophy > 150 Psychology
600 Technology > 610 Medicine & health

ISSN:

1935-861X

Publisher:

Elsevier

Language:

English

Submitter:

Vanessa Vallejo

Date Deposited:

16 Mar 2017 13:50

Last Modified:

02 May 2017 01:37

Publisher DOI:

10.1016/j.brs.2017.01.001

PubMed ID:

28089321

Uncontrolled Keywords:

Consolidation; Dorsolateral prefrontal cortex; Implicit task sequence learning; Transcranial direct current stimulation

BORIS DOI:

10.7892/boris.94027

URI:

https://boris.unibe.ch/id/eprint/94027

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