Stoop, Matthias; Leumann, Christian J. (2011). Homo-DNA templated chemistry and its application to nucleic acid sensing. Chemical communications, 47(26), pp. 7494-7496. Cambridge: Royal Society of Chemistry 10.1039/C1CC11469G
![[img]](https://boris.unibe.ch/style/images/fileicons/text.png) |
Text
c1cc11469g.pdf - Published Version Restricted to registered users only Available under License Publisher holds Copyright. Download (1MB) |
We have investigated the homo-DNA templated Staudinger reduction of the profluorophore rhodamine azide and have applied this reaction to the detection of natural DNA with a hybrid homo-DNA/DNA molecular beacon. In this system the sensing and the reporting unit are bioorthogonal to each other which facilitates sequence design and increases fidelity.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP) |
UniBE Contributor: |
Stoop, Matthias, Leumann, Christian |
Subjects: |
500 Science > 570 Life sciences; biology 500 Science > 540 Chemistry |
ISSN: |
1359-7345 |
Publisher: |
Royal Society of Chemistry |
Language: |
English |
Submitter: |
Christian Leumann |
Date Deposited: |
04 Oct 2013 14:26 |
Last Modified: |
05 Dec 2022 14:07 |
Publisher DOI: |
10.1039/C1CC11469G |
Web of Science ID: |
000291823400062 |
BORIS DOI: |
10.7892/boris.9417 |
URI: |
https://boris.unibe.ch/id/eprint/9417 (FactScience: 215150) |
Actions (login required)
 |
Edit item |