Our Mothers' Antibodies as Guardians of our Commensals.

Ganal-Vonarburg, Stephanie; Macpherson, Andrew (2016). Our Mothers' Antibodies as Guardians of our Commensals. Trends in molecular medicine, 22(9), pp. 739-741. Cell Press 10.1016/j.molmed.2016.06.010

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Mucosal secretory IgA protects the mammalian body from invasion of commensal bacteria colonizing the intestine. A recent murine study in Cell shows that commensal-specific antibodies of the IgG isotype are also present in the serum and that maternal commensal-specific IgA and IgG are crucial for maintaining host-microbe mutualism in the offspring.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Gastroenterology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Gastroenterologie / Mukosale Immunologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Gastroenterologie / Mukosale Immunologie

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine

UniBE Contributor:

Ganal-Vonarburg, Stephanie and Macpherson, Andrew

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1471-4914

Publisher:

Cell Press

Language:

English

Submitter:

Lilian Karin Smith-Wirth

Date Deposited:

03 May 2017 10:20

Last Modified:

08 May 2017 10:13

Publisher DOI:

10.1016/j.molmed.2016.06.010

PubMed ID:

27396513

BORIS DOI:

10.7892/boris.94421

URI:

https://boris.unibe.ch/id/eprint/94421

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