Fertility preservation practices in pediatric and adolescent cancer patients undergoing HSCT in Europe: a population-based survey.

Diesch, T; Rovó, Alicia; von der Weid, N; Faraci, M; Pillon, M; Dalissier, A; Dalle, J-H; Bader, P (2017). Fertility preservation practices in pediatric and adolescent cancer patients undergoing HSCT in Europe: a population-based survey. Bone marrow transplantation, 52(7), pp. 1022-1028. Nature Publishing Group 10.1038/bmt.2016.363

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Chemotherapy and irradiation can affect the gonads, leading to impairment of pubertal development and/or infertility. Fertility preservation (FP) is therefore a crucial endeavor in hematopoietic stem cell transplantation (HSCT) because of the severe impact of infertility on the quality of life of long-term survivors. Despite the existence of different international guidelines, FP counseling and procedures are not routinely implemented as part of patient care. We present herein a survey conducted by the Pediatric Working Party of the European Society for Blood and Marrow Transplantation (EBMT), which aims to analyze and compare different FP practices for children and adolescents across EBMT centers in 2013. A total of 177 pediatric centers reporting to the EBMT were contacted; of this number, 38 centers (21%) located in 16 different countries responded. These centers reported 834 patients receiving HSCT in 2013 (73% prepubertal), corresponding to 22% of all children (n=3789) undergoing HSCT in EBMT reporting centers. Overall, 39% of the reported patients received counseling and 29% received an FP procedure. The increased need for FP programs, extended education for patient-care teams, and more personal resources and funding emerged from this survey as pivotal factors necessary to support and implement such programs.Bone Marrow Transplantation advance online publication, 23 January 2017; doi:10.1038/bmt.2016.363.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Haematology and Central Haematological Laboratory

UniBE Contributor:

Rovó, Alicia

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0268-3369

Publisher:

Nature Publishing Group

Language:

English

Submitter:

Katrin Kölliker-Schütz

Date Deposited:

13 Apr 2017 12:01

Last Modified:

07 Jul 2017 07:40

Publisher DOI:

10.1038/bmt.2016.363

PubMed ID:

28112743

Uncontrolled Keywords:

Rovó Alicia

BORIS DOI:

10.7892/boris.94423

URI:

https://boris.unibe.ch/id/eprint/94423

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