Sleep disturbance impairs stroke recovery in the rat

Zunzunegui, Cristina; Gao, Bo; Cam, Ertugrul; Hodor, Aleksandra; Bassetti, Claudio L (2011). Sleep disturbance impairs stroke recovery in the rat. Sleep, 34(9), pp. 1261-9. Darien, Ill.: American Academy of Sleep Medicine 10.5665/SLEEP.1252

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There is a lack of experimental evidence to support the hypothesis that sleep may modulate stroke outcome as suggested by clinical observations. We have previously shown that sleep disturbance (SDis) over 3 days aggravates brain damage in a rat model of focal cerebral ischemia. The aim of this study is to further investigate effects of SDis on long-term stroke recovery and neuroplasticity as assessed by axonal sprouting, neurogenesis, and angiogenesis.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

Bassetti, Claudio L.A.

ISSN:

0161-8105

Publisher:

American Academy of Sleep Medicine

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:26

Last Modified:

02 Mar 2023 23:21

Publisher DOI:

10.5665/SLEEP.1252

PubMed ID:

21886364

Web of Science ID:

000294481700017

URI:

https://boris.unibe.ch/id/eprint/9449 (FactScience: 215186)

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