Diagnostic accuracy of plasma glial fibrillary acidic protein for differentiating intracerebral hemorrhage and cerebral ischemia in patients with symptoms of acute stroke

Foerch, Christian; Niessner, Marion; Back, Tobias; Bauerle, Michael; De Marchis, Gian Marco; Ferbert, Andreas; Grehl, Holger; Hamann, Gerhard F; Jacobs, Andreas; Kastrup, Andreas; Klimpe, Sven; Palm, Frederick; Thomalla, Götz; Worthmann, Hans; Sitzer, Matthias; BE FAST Study Group, (2012). Diagnostic accuracy of plasma glial fibrillary acidic protein for differentiating intracerebral hemorrhage and cerebral ischemia in patients with symptoms of acute stroke. Clinical chemistry, 58(1), pp. 237-45. Washington, D.C.: American Association for Clinical Chemistry 10.1373/clinchem.2011.172676

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Glial fibrillary acidic protein (GFAP) is a biomarker candidate indicative of intracerebral hemorrhage (ICH) in patients with symptoms of acute stroke. GFAP is released rapidly in the presence of expanding intracerebral bleeding, whereas a more gradual release occurs in ischemic stroke. In this study the diagnostic accuracy of plasma GFAP was determined in a prospective multicenter approach.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

De Marchis, Gian Marco

ISSN:

0009-9147

Publisher:

American Association for Clinical Chemistry

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:26

Last Modified:

17 Mar 2015 21:09

Publisher DOI:

10.1373/clinchem.2011.172676

PubMed ID:

22125303

Web of Science ID:

000299052700037

URI:

https://boris.unibe.ch/id/eprint/9459 (FactScience: 215196)

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