Alveolar inflammation in cystic fibrosis

Ulrich, Martina; Worlitzsch, Dieter; Viglio, Simona; Siegmann, Nanna; Iadarola, Paolo; Shute, Janis K; Geiser, Marianne; Pier, Gerald B; Friedel, Godehard; Barr, Mark L; Schuster, Antje; Meyer, Keith C; Ratjen, Felix; Bjarnsholt, Thomas; Gulbins, Erich; Döring, Gerd (2010). Alveolar inflammation in cystic fibrosis. Journal of cystic fibrosis, 9(3), pp. 217-27. Amsterdam: Elsevier 10.1016/j.jcf.2010.03.001

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In infected lungs of the cystic fibrosis (CF) patients, opportunistic pathogens and mutated cystic fibrosis transmembrane conductance regulator protein (CFTR) contribute to chronic airway inflammation that is characterized by neutrophil/macrophage infiltration, cytokine release and ceramide accumulation. We sought to investigate CF lung inflammation in the alveoli.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy > Cell Biology
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy

UniBE Contributor:

Geiser, Marianne

ISSN:

1569-1993

Publisher:

Elsevier

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:09

Last Modified:

18 Jan 2017 10:29

Publisher DOI:

10.1016/j.jcf.2010.03.001

PubMed ID:

20347403

Web of Science ID:

000279029400010

URI:

https://boris.unibe.ch/id/eprint/946 (FactScience: 201543)

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