Prevalence and Mechanisms of Peri-implant Diseases.

Salvi, Giovanni Edoardo; Cosgarea, R; Sculean, Anton (2017). Prevalence and Mechanisms of Peri-implant Diseases. Journal of dental research, 96(1), pp. 31-37. Sage 10.1177/0022034516667484

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The aim of the present critical review is to summarize recent evidence on the prevalence of peri-implant diseases and their similarities and differences with periodontal diseases with a focus on their pathogenetic mechanisms. Reports on the extent and severity of peri-implant diseases are influenced by different case definitions. The prevalence of peri-implant diseases is reported at the subject or implant level and affected by the type of population samples analyzed (e.g., randomly selected population samples or convenience samples). The outcomes of studies on animals and humans indicate that experimental biofilm accumulation leads to a higher frequency of bleeding sites around implants as compared with teeth. Despite the proof of principle that experimentally induced mucositis may be reversible, early diagnosis and management of naturally occurring peri-implant mucositis are clinically relevant. Tissue destruction at experimental peri-implantitis sites is faster and more extensive when compared with that at experimental periodontitis sites. Although human periodontitis and peri-implantitis lesions share similarities with respect to etiology and clinical features, they represent distinct entities from a histopathologic point of view. To avoid implant loss, patients diagnosed with peri-implantitis should be treated without delay.

Item Type:

Journal Article (Further Contribution)


04 Faculty of Medicine > School of Dental Medicine > Department of Periodontology
04 Faculty of Medicine > School of Dental Medicine

UniBE Contributor:

Salvi, Giovanni Edoardo and Sculean, Anton


600 Technology > 610 Medicine & health








Eveline Carmen Schuler

Date Deposited:

10 May 2017 12:40

Last Modified:

10 May 2017 12:40

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

epidemiology, implant dentistry/implantology, Inflammation, peri-implant infection(s), periodontal disease(s)/Periodontitis, plaque/plaque biofilms




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