Soft tissue augmentation procedures at second-stage surgery: a systematic review.

Bassetti, Renzo G; Stähli, Alexandra; Bassetti, Mario A; Sculean, Anton (2016). Soft tissue augmentation procedures at second-stage surgery: a systematic review. Clinical oral investigations, 20(7), pp. 1369-1387. Springer 10.1007/s00784-016-1815-2

[img] Text
Soft tissue augmentation procedures at second-stage surgery_ a systematic review.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (595kB) | Request a copy

OBJECTIVES The aim of this systematic review was to evaluate the efficacy of different soft tissue augmentation/correction methods in terms of increasing the peri-implant width of keratinized mucosa (KM) and/or gain of soft tissue volume during second-stage surgery. MATERIALS AND METHODS Screening of two databases, MEDLINE (PubMed) and EMBASE (OVID), and hand search of related articles, were performed. Human studies reporting on soft tissue augmentation/correction methods around submucosally osseointegrated implants during second-stage surgery up to July 31, 2015 were considered. Quality assessment of the selected full-text articles was performed according to the Cochrane collaboration's tool to assess the risk of bias. RESULTS Overall, eight prospective studies (risk of bias: high) and two case series (risk of bias: high) were included. Depending on the surgical technique and graft material used, the enlargement of keratinized tissue (KT) ranged between -0.20 and 9.35 mm. An apically positioned partial-thickness flap/vestibuloplasty (APPTF/VP) in combination with a free gingival graft (FGG) or a xenogeneic graft material (XCM) was most effective. Applying a roll envelope flap (REF) or an APPTF in combination with a subepithelial connective tissue graft (SCTG), mean increases in soft tissue volumes of 2.41 and 3.10 mm, respectively, were achieved. Due to the heterogeneity of study designs, no meta-analysis could be performed. CONCLUSIONS Within the limitations of this review, regarding the enlargement of peri-implant KT, the APPTF in the maxilla and the APPTF/VP in combination with FGG or XCM in the lower and upper jaw seem to provide acceptable outcomes. To augment peri-implant soft tissue volume REF in the maxilla or APPTF + SCTG in the lower and upper jaw appear to be reliable treatment options. CLINICAL RELEVANCE The localization in the jaw and the clinical situation are crucial for the decision which second-stage procedure should be applied.

Item Type:

Journal Article (Review Article)


04 Faculty of Medicine > School of Dental Medicine > Department of Periodontology
04 Faculty of Medicine > School of Dental Medicine

UniBE Contributor:

Stähli, Alexandra and Sculean, Anton


600 Technology > 610 Medicine & health








Eveline Carmen Schuler

Date Deposited:

08 May 2017 09:39

Last Modified:

08 May 2017 09:39

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

Peri-implant keratinized mucosa, Peri-implant soft tissue volume, Re-entry, Second-stage surgery




Actions (login required)

Edit item Edit item
Provide Feedback