Giannini, Federico; Süss-Fink, Gerog; Furrer, Julien (2011). Efficient Oxidation of Cysteine and Glutathione Catalyzed by a Dinuclear Areneruthenium Trithiolato Anticancer Complex. Inorganic chemistry, 50(21), pp. 10552-10554. Washington, D.C.: American Chemical Society 10.1021/ic201941j
Full text not available from this repository.The highly cytotoxic diruthenium complex [(p-MeC(6)H(4)Pr(1))(2)Ru(2)(SC(6)H(4)-p-Me)(3)](+) (1), water-soluble as the chloride salt, is shown to efficiently catalyze oxidation of the thiols cysteine and glutathione to give the corresponding disulfides, which may explain its high in vitro anticancer activity.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP) |
UniBE Contributor: |
Furrer, Julien |
Subjects: |
500 Science > 570 Life sciences; biology 500 Science > 540 Chemistry |
ISSN: |
0020-1669 |
Publisher: |
American Chemical Society |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:26 |
Last Modified: |
05 Dec 2022 14:08 |
Publisher DOI: |
10.1021/ic201941j |
Web of Science ID: |
000296303900013 |
URI: |
https://boris.unibe.ch/id/eprint/9527 (FactScience: 215276) |
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