European multicenter study on antimicrobial resistance in bacteria isolated from companion animal urinary tract infections.

Marques, Cátia; Gama, Luís Telo; Belas, Adriana; Bergström, Karin; Beurlet, Stéphanie; Briend-Marchal, Alexandra; Broens, Els M; Costa, Marta; Criel, Delphine; Damborg, Peter; van Dijk, Marloes A M; van Dongen, Astrid M; Dorsch, Roswitha; Espada, Carmen Martin; Gerber, Bernhard; Kritsepi-Konstantinou, Maria; Loncaric, Igor; Mion, Domenico; Misic, Dusan; Movilla, Rebeca; ... (2016). European multicenter study on antimicrobial resistance in bacteria isolated from companion animal urinary tract infections. BMC veterinary research, 12(1), p. 213. BioMed Central 10.1186/s12917-016-0840-3

[img] Text
s12917-016-0840-3 - Published Version
Available under License Creative Commons: Attribution (CC-BY).

Download (8MB)

BACKGROUND

There is a growing concern regarding the increase of antimicrobial resistant bacteria in companion animals. Yet, there are no studies comparing the resistance levels of these organisms in European countries. The aim of this study was to investigate geographical and temporal trends of antimicrobial resistant bacteria causing urinary tract infection (UTI) in companion animals in Europe. The antimicrobial susceptibility of 22 256 bacteria isolated from dogs and cats with UTI was determined. Samples were collected between 2008 and 2013 from 16 laboratories of 14 European countries. The prevalence of antimicrobial resistance of the most common bacteria was determined for each country individually in the years 2012-2013 and temporal trends of bacteria resistance were established by logistic regression.

RESULTS

The aetiology of uropathogenic bacteria differed between dogs and cats. For all bacterial species, Southern countries generally presented higher levels of antimicrobial resistance compared to Northern countries. Multidrug-resistant Escherichia coli were found to be more prevalent in Southern countries. During the study period, the level of fluoroquinolone-resistant E. coli isolated in Belgium, Denmark, France and the Netherlands decreased significantly. A temporal increase in resistance to amoxicillin-clavulanate and gentamicin was observed among E. coli isolates from the Netherlands and Switzerland, respectively. Other country-specific temporal increases were observed for fluoroquinolone-resistant Proteus spp. isolated from companion animals from Belgium.

CONCLUSIONS

This work brings new insights into the current status of antimicrobial resistance in bacteria isolated from companion animals with UTI in Europe and reinforces the need for strategies aiming to reduce resistance.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Veterinary Bacteriology > Molecular Bacterial Epidemiology and Infectiology
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Veterinary Bacteriology

UniBE Contributor:

Overesch, Gudrun and Perreten, Vincent

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

1746-6148

Publisher:

BioMed Central

Language:

English

Submitter:

Vincent Perreten

Date Deposited:

10 Jul 2017 08:32

Last Modified:

16 Jul 2017 02:13

Publisher DOI:

10.1186/s12917-016-0840-3

PubMed ID:

27658466

Uncontrolled Keywords:

Antimicrobial resistance; Cat; Dog; MRSA; MRSP; Temporal trends

BORIS DOI:

10.7892/boris.95372

URI:

https://boris.unibe.ch/id/eprint/95372

Actions (login required)

Edit item Edit item
Provide Feedback