Mammary immunoglobulin transfer rates following prepartum milking.

Baumrucker, Craig; Dechow, C D; Macrina, A L; Gross, Josef Johann; Bruckmaier, Rupert (2016). Mammary immunoglobulin transfer rates following prepartum milking. Journal of dairy science, 99(11), pp. 9254-9262. American Dairy Science Association 10.3168/jds.2016-11370

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Colostrum formation is thought to occur slowly over an extended period (4wk) prepartum. Furthermore, colostrum formation is highly variable among cows in total volume, IgG1 concentration, and mass obtained at first postpartum milking. Recent work has suggested that a rapid transfer of IgG1 to secretions may occur if animals are milked prepartum. Our objective was to establish the concentration, mass, and mass transfer rates of IgG1 in multiparous Holstein cows (n=11, parity=3.6±1.1) milked prepartum (-74 to -1h) and again around 4h postpartum. Blood concentrations of IgG1 were very low (<1mg/mL) in 7 cows at prepartum milking and did not decline following prepartum milking. Cows showed variability in the capacity to recover total volume, IgG1 concentration, and IgG1 mass. Three groupings of cows were considered based on the time between the 2 milkings (prepartum + 4h postpartum): long-time (-74 to -54h, n=3), medium-time (-25 to -17h, n=4), and short-time (< -13h, n=4) groups. The average rates of transfer of these groups were 1.4±0.8, 3.0±1.3, and 25.1±15.8g/h, respectively. The data indicate that a longer time between prepartum and postpartum milking is not a main factor in IgG1 secretion transfer. Furthermore, because blood concentrations did not change after prepartum milking and the mass of blood plasma IgG1 was not sufficient to account for the mass occurring in postpartum colostrum, a source of IgG1 other than blood circulation appears to be present during colostrogenesis.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Veterinary Physiology
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH)

UniBE Contributor:

Baumrucker, Craig; Gross, Josef Johann and Bruckmaier, Rupert

Subjects:

500 Science > 570 Life sciences; biology

ISSN:

0022-0302

Publisher:

American Dairy Science Association

Language:

English

Submitter:

Lorenzo Enrique Hernandez Castellano

Date Deposited:

24 Jul 2017 08:24

Last Modified:

24 Jul 2017 08:24

Publisher DOI:

10.3168/jds.2016-11370

PubMed ID:

27568047

Uncontrolled Keywords:

colostrum; immunoglobulin; mammary; transfer rates

BORIS DOI:

10.7892/boris.95426

URI:

https://boris.unibe.ch/id/eprint/95426

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