IgE-associated allergic disorders: recent advances in etiology, diagnosis, and treatment.

Zellweger, Fabian; Eggel, Alexander (2016). IgE-associated allergic disorders: recent advances in etiology, diagnosis, and treatment. Allergy, 71(12), pp. 1652-1661. Wiley-Blackwell 10.1111/all.13059

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IgE-associated allergic diseases belong to the most common inflammatory conditions. Their clinical manifestation ranges from mild symptoms to life-threatening episodes. Often patients experience a reduction in physical and psychologic well-being and suffer from a decreased quality of life due to disease activity. The continuously rising number of people that are affected by an allergic condition indicates an urgent need for better diagnostics and more efficient treatment options. Recent progress in the understanding of pathophysiologic mechanisms underlying IgE-associated allergic disorders has led to the identification of novel therapeutic targets and the development of drug candidates that are currently under evaluation. In this review, we highlight studies and clinical trials, which have helped to gain further insight in the etiology of IgE-associated allergic conditions as well as advances in the development of diagnostic tools and therapeutic approaches recently published in Allergy (European Journal of Allergy and Clinical Immunology).

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Institute for Immunology (discontinued)
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Rheumatology, Clinical Immunology and Allergology

UniBE Contributor:

Zellweger, Fabian and Eggel, Alexander

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0105-4538

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Stefan Kuchen

Date Deposited:

17 May 2017 13:15

Last Modified:

17 May 2017 13:15

Publisher DOI:

10.1111/all.13059

PubMed ID:

27709638

Uncontrolled Keywords:

IgE; IgE-associated allergic diseases; diagnosis; prevention; therapy

BORIS DOI:

10.7892/boris.95686

URI:

https://boris.unibe.ch/id/eprint/95686

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