How to measure disease activity in eosinophilic esophagitis.

Schoepfer, A; Safroneeva, Ekaterina; Straumann, A (2016). How to measure disease activity in eosinophilic esophagitis. Diseases of the esophagus, 29(8), pp. 959-966. Blackwell Asia 10.1111/dote.12391

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Activity of Eosinophilic Esophagitis (EoE) can be measured by patient reported outcomes (symptoms and quality of life) and clinician-reported outcomes (endoscopic, histologic, or biochemical alterations). Over the last years efforts have been underway to develop and validate instruments to assess EoE activity in the different domains. Such instruments are urgently needed to standardize the language of EoE activity assessment and, in so doing, to facilitate communication among various stakeholders. Such standardization will ultimately allow EoE researchers to define meaningful endpoints for use in clinical trials and observational studies, to compare the efficacy of different therapeutic modalities, and to develop algorithms in order to provide patients with the appropriate therapy. This review provides an overview of the current status of instruments that assess EoE activity in the different domains.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine

UniBE Contributor:

Safroneeva, Ekaterina

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

1120-8694

Publisher:

Blackwell Asia

Language:

English

Submitter:

Doris Kopp Heim

Date Deposited:

16 Feb 2017 13:39

Last Modified:

16 Sep 2017 04:55

Publisher DOI:

10.1111/dote.12391

PubMed ID:

26227624

Uncontrolled Keywords:

eosinophilic esophagitis; patient reported outcomes; quality of life; eosinophils; disease activity

BORIS DOI:

10.7892/boris.95980

URI:

https://boris.unibe.ch/id/eprint/95980

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