Hypertensive retinopathy and choroidopathy associated to hyperaldosteronism and secondary hyperparathyroidism in a cat

Abarca Piedrafita, Eva Maria; Obrador de Aguilar, Rafael; Closa, Jose Maria; Ramis, Antonio; Font, Arturo (2013). Hypertensive retinopathy and choroidopathy associated to hyperaldosteronism and secondary hyperparathyroidism in a cat. Clinica veterinaria de pequeños animales, 33(1), pp. 35-40. AVEPA Official Journal

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A 9 year-old neutered male Persian cat was presented with a sudden onset of disorientation and blindness. Ophthalmoscopy showed retinal periarteriolar transudates in both eyes. Blood work revealed moderate anemia, mild azotemia, severe hypernatremia and hypercalcemia. Systolic 220 mmHg (125 + 12) and diastolic 110 mmHg (86+15) arterial blood pressure using the oscillometric technique showed severe systemic hypertension. The abdominal ultrasound revealed enlarged bilateral adrenal glands and the echocardiography showed left ventricular hypertrophy. Primary hyperaldosteronism was diagnosed by demonstrating high aldosterone levels in the presence of suppressed plasma renin activity. On the basis of severe hypercalcemia and normal PTH levels a secondary renal hyperparathyroidism or associated with hyperaldosteronism was elicited. Amlodipine besylate (Norvas, Pfizer, Madrid, España) 0.625 mg PO s.i.d and spironolactone (Aldactone, Pharmacia, Barcelona, España) 2 mg/kg sid PO were administered as treatment. The ocular fundus was studied over a 390 day period and showed the evolution of hypertensive retinopathy and choroidopathy lesions over this period. The patient was euthanized on day 390 due to terminal renal failure. Histological study confirmed bilateral adrenal hyperplasia, parathyroid hyperplasia, as well as lesions of hypertensive choroidopathy and retinopathy and hypertensive encephalopathy.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV)
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Small Animal Clinic

UniBE Contributor:

Abarca Piedrafita, Eva Maria and Obrador de Aguilar, Rafael

Subjects:

600 Technology > 630 Agriculture
500 Science > 570 Life sciences; biology
500 Science > 590 Animals (Zoology)

ISSN:

1130-7064

Publisher:

AVEPA Official Journal

Language:

Español

Submitter:

Eva Maria Abarca Piedrafita

Date Deposited:

11 Aug 2017 15:55

Last Modified:

11 Aug 2017 16:00

URI:

https://boris.unibe.ch/id/eprint/97608

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