PRELIMINARY EVALUATION OF SPIROTOME® DEVICE FOR LIVER BIOPSY IN GREEN IGUANAS (IGUANA IGUANA): A PILOT STUDY.

Nardini, Giordano; Origgi, Francesco; Leopardi, Stefania; Zaghini, Anna; Saunders, Jimmy H; Vignoli, Massimo (2016). PRELIMINARY EVALUATION OF SPIROTOME® DEVICE FOR LIVER BIOPSY IN GREEN IGUANAS (IGUANA IGUANA): A PILOT STUDY. Journal of zoo and wildlife medicine, 47(2), pp. 508-513. BioOne 10.1638/2014-0217.1

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The aim of this study was to evaluate a large-core manual biopsy device (Spirotome(®), Medinvents, 3500 Hasselt, Belgium) for liver sampling and histologic diagnosis in green iguanas (Iguana iguana). The study included eight green iguanas, and two ultrasound-guided biopsies were collected for each lizard, for 16 biopsies in total. The procedure was carried out under general anesthesia induced by intravenous injection of propofol (10 mg/kg) maintained with a mixture of 2.0% isoflurane and 0.8-1.2 L/min oxygen after tracheal intubation. Fourteen (87.5%) of the 16 biopsies were considered diagnostic. Liver biopsy quality was assessed according to sample size and tissue preservation. In particular, mean length (16.2 ± 4.5 mm), width (2.2 ± 0.5 mm), area (34.8 ± 6.9 mm(2)), and number of portal areas (9.4 ± 3.9) of each biopsy were recorded for all green iguanas. The total available surface of the sections obtained from the biopsies and their grade of preservation enabled a satisfactory evaluation of the parenchymal architecture. One of the green iguanas in the study died the day after the procedure due to severe hemocoeloma. Risk assessment evaluation suggested that small green iguanas may not be suitable for this biopsy procedure.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Center for Fish and Wildlife Health (FIWI)

UniBE Contributor:

Origgi, Francesco

Subjects:

600 Technology > 630 Agriculture

ISSN:

1042-7260

Publisher:

BioOne

Language:

English

Submitter:

Lucia Gugger-Raaflaub

Date Deposited:

24 Jul 2017 15:53

Last Modified:

24 Jul 2017 15:53

Publisher DOI:

10.1638/2014-0217.1

PubMed ID:

27468023

Uncontrolled Keywords:

Iguana iguana; Spirotome; liver biopsy; lizard; ultrasound

URI:

https://boris.unibe.ch/id/eprint/97745

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