Histopathological alterations of the heart in fish: proposal for a standardized assessment.

Steinbach, Christoph; Kroupová, Hana Kocour; Wahli, Thomas; Klicnarová, Jana; Schmidt-Posthaus, Heike (2016). Histopathological alterations of the heart in fish: proposal for a standardized assessment. Diseases of aquatic organisms, 118(3), pp. 185-194. Inter-Research 10.3354/dao02971

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Histopathological alterations in the heart are often reported in fish as a result of exposure to a variety of chemical compounds. However, researchers presently lack a standardized method for the evaluation of histopathological alterations in the cardiovascular system of fish and the calculation of an 'organ index'. Therefore, we designed a method for a standardized assessment and evaluation of histopathological alterations in the heart of fish. As a model species, we used rainbow trout Oncorhynchus mykiss, but the protocol was also successfully applied to other fish species belonging to different taxonomic orders. To test the protocol, we re-evaluated sections of atenolol-exposed and unexposed rainbow trout obtained in a previous study. The results were in accordance with those previously published, demonstrating the applicability of the protocol. The protocol provides a universal method for the comparative evaluation of histopathological changes in the heart of fish.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Center for Fish and Wildlife Health (FIWI)

UniBE Contributor:

Steinbach, Christoph; Wahli, Thomas and Schmidt-Posthaus, Heike

Subjects:

600 Technology > 630 Agriculture

ISSN:

0177-5103

Publisher:

Inter-Research

Language:

English

Submitter:

Lucia Gugger-Raaflaub

Date Deposited:

21 Jul 2017 13:19

Last Modified:

21 Jul 2017 13:19

Publisher DOI:

10.3354/dao02971

PubMed ID:

27025306

BORIS DOI:

10.7892/boris.97754

URI:

https://boris.unibe.ch/id/eprint/97754

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