Highly conserved genes coding for eukaryotic translation initiation factor eIF-4A of tobacco have specific alterations in functional motifs

Brander, Karl A; Mandel, Therese; Owttrim, George W; Kuhlemeier, Cris (1995). Highly conserved genes coding for eukaryotic translation initiation factor eIF-4A of tobacco have specific alterations in functional motifs. Biochimica et biophysica acta (BBA) - gene structure and expression, 1261(3), pp. 442-444. Elsevier 10.1016/0167-4781(95)00052-I

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Eukaryotic translation initiation factor eIF-4A is an ATP-dependent RNA helicase that is required for the binding of mRNA to ribosomes. Plant eIF-4A-like proteins are highly homologous to eIF-4As from yeast, mouse and Drosophila melanogaster. The pattern of intron-exon boundaries in eIF-4A-like genes are conserved within tobacco, but are not conserved with other organisms. Fixed spacings between the functionally important sequence motifs, GKT-PTRELA (72 bp), DEAD-SAT (81 bp) and SAT-HRIGR (426 bp), are conserved between plants, mouse, Drosophila and yeast.

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Department of Biology > Institute of Plant Sciences (IPS) > Plant Development
08 Faculty of Science > Department of Biology > Institute of Plant Sciences (IPS)

UniBE Contributor:

Mandel, Therese and Kuhlemeier, Cris

Subjects:

500 Science > 580 Plants (Botany)

ISSN:

0167-4781

Publisher:

Elsevier

Language:

English

Submitter:

Peter Alfred von Ballmoos-Haas

Date Deposited:

05 Jul 2017 10:11

Last Modified:

21 Jul 2017 09:40

Publisher DOI:

10.1016/0167-4781(95)00052-I

Uncontrolled Keywords:

RNA-unwinding; RNA-helicase; DEAD-box protein; gene family; tobacco

BORIS DOI:

10.7892/boris.97865

URI:

https://boris.unibe.ch/id/eprint/97865

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