Human papillomavirus vaccination and genital warts in young Indigenous Australians: national sentinel surveillance data.

Ali, Hammad; McManus, Hamish; O'Connor, Catherine C; Callander, Denton; Kong, Marlene; Graham, Simon; Saulo, Dina; Fairley, Christopher K; Regan, David G; Grulich, Andrew; Low, Nicola; Guy, Rebecca J; Donovan, Basil (2017). Human papillomavirus vaccination and genital warts in young Indigenous Australians: national sentinel surveillance data. Medical Journal of Australia, 206(5), pp. 204-209. Australasian Medical Publishing Company Ltd

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OBJECTIVES

To examine the impact of the national human papillomavirus (HPV) vaccination program (available to girls and women [12-26 years] since 2007 and to boys [12-15 years] since 2013) on the number of diagnoses of genital warts in Australian Aboriginal and Torres Strait Islander (Indigenous) people.

DESIGN, SETTING, PARTICIPANTS

Analysis of routinely collected data from patients attending 39 sexual health clinics (SHCs) in the Genital Warts Surveillance Network for the first time.Major outcome: The average annual proportion of Indigenous and non-Indigenous SHC patients diagnosed with genital warts during the pre-vaccination (2004-2007) and vaccination periods (2008-2014), stratified by age group and sex.

RESULTS

7.3% of the 215 599 Australian-born patients with known Indigenous status and seen for the first time at participating SHCs during 2004-2014 were Indigenous Australians. The average proportion of female Indigenous patients diagnosed with warts was lower during the vaccination period than during the pre-vaccination period (in those under 21, summary rate ratio [SRR], 0.12; 95% CI, 0.07-0.21; P < 0.001); in 21-30-year olds: SRR, 0.41; 95% CI, 0.27-0.61; P < 0.001); there was no significant difference for women over 30 (SRR, 0.84; 95% CI, 0.51-1.36; P = 0.47). The proportion of male Indigenous heterosexual SHC patients under 21 diagnosed with warts was also lower during the vaccination period (SRR, 0.25; 95% CI, 0.12-0.49; P < 0.001), with no significant changes among older Indigenous men over 30.

CONCLUSIONS

There were marked declines in the proportions of diagnoses of genital warts in young Indigenous women and men attending SHCs after the introduction of the HPV vaccination program. If high levels of HPV vaccine coverage are sustained, HPV-related cancer rates should also decline.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM)

UniBE Contributor:

Low, Nicola

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

0025-729X

Publisher:

Australasian Medical Publishing Company Ltd

Language:

English

Submitter:

Doris Kopp Heim

Date Deposited:

04 Apr 2017 15:41

Last Modified:

05 Dec 2022 15:04

PubMed ID:

28301790

BORIS DOI:

10.7892/boris.99081

URI:

https://boris.unibe.ch/id/eprint/99081

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