Effects on hemodynamic variables and echocardiographic parameters after a stellate ganglion block in 15 healthy volunteers

Puente de la Vega Costa, Katia Pilar; Gómez Perez, Miquel A.; Roqueta, Cristina; Fischer, Lorenz (2016). Effects on hemodynamic variables and echocardiographic parameters after a stellate ganglion block in 15 healthy volunteers. Autonomic Neuroscience: Basic and Clinical, 197, pp. 46-55. Elsevier 10.1016/j.autneu.2016.04.002

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Background: The sympathetic nervous system has an important role in generating pain. Various pathomechanisms are involved that respond well to the application of local anesthetics (LA), for example to the stellate ganglion block (SGB). Objectives:We wanted to know more about the effects of SGB on cardiovascular parameters. Methods:Weincluded 15 healthy volunteers; another 15 healthy volunteers as a control group (shaminjection of LA). In order to produce a more precise SGB, we employed only a small volume of LA (3 mL), a LA with a lower permeability (procaine 1%), and amodified injection technique. Systolic and diastolic blood pressure (SBP, DBP), heart rate (HR), and echocardiographic parameters were recorded before and after SGB. We also investigated whether there are side differences (left and right SBG). Results: At baseline all parameterswere within the normal range. After performing right and left SGB DBP significantly increased (on the right side from68.73±8.61 to 73.53±11.10, p=0.015; on the left side from70.66± 13.01 to 77.93 ± 10.40, p = 0.003). In the control group no increase in DBP was observed. No side-specific differences were found, except a significant reduction in the maximum velocity of myocardial contraction during the systole with left-sided SGB. Conclusions: Even with our methods we could not prevent the simultaneous occurrence of a partial parasympatholytic effect. For this reason, the SGB has only minor hemodynamic effects, which is desirable as it enhances the safety of the SGB.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Medical Education > Institute of Complementary Medicine (ICOM)

UniBE Contributor:

Puente de la Vega Costa, Katia Pilar and Fischer, Lorenz

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1566-0702

Publisher:

Elsevier

Language:

English

Submitter:

Lorenz Fischer

Date Deposited:

24 May 2017 11:23

Last Modified:

24 May 2017 13:28

Publisher DOI:

10.1016/j.autneu.2016.04.002

PubMed ID:

27143533

Uncontrolled Keywords:

Echocardiographic parameters; Hemodynamic parameters; Local anesthesia; Neural therapy; Procaine; Stellate ganglion block

BORIS DOI:

10.7892/boris.99168

URI:

https://boris.unibe.ch/id/eprint/99168

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