Effects on hemodynamic variables and echocardiographic parameters after a stellate ganglion block in 15 healthy volunteers

Puente de la Vega Costa, Katia; Gómez Perez, Miquel A.; Roqueta, Cristina; Fischer, Lorenz (2016). Effects on hemodynamic variables and echocardiographic parameters after a stellate ganglion block in 15 healthy volunteers. Autonomic Neuroscience: Basic and Clinical, 197, pp. 46-55. Elsevier 10.1016/j.autneu.2016.04.002

PIIS1566070216300352.pdf - Published Version
Available under License Creative Commons: Attribution-Noncommercial-No Derivative Works (CC-BY-NC-ND).

Download (940kB) | Preview

Background: The sympathetic nervous system has an important role in generating pain. Various
pathomechanisms are involved that respond well to the application of local anesthetics (LA), for example to
the stellate ganglion block (SGB).
Objectives:We wanted to know more about the effects of SGB on cardiovascular parameters.
Methods:Weincluded 15 healthy volunteers; another 15 healthy volunteers as a control group (shaminjection of
LA). In order to produce a more precise SGB, we employed only a small volume of LA (3 mL), a LA with a lower
permeability (procaine 1%), and amodified injection technique. Systolic and diastolic blood pressure (SBP, DBP),
heart rate (HR), and echocardiographic parameters were recorded before and after SGB. We also investigated
whether there are side differences (left and right SBG).
Results: At baseline all parameterswere within the normal range. After performing right and left SGB DBP significantly
increased (on the right side from68.73±8.61 to 73.53±11.10, p=0.015; on the left side from70.66±
13.01 to 77.93 ± 10.40, p = 0.003). In the control group no increase in DBP was observed. No side-specific differences
were found, except a significant reduction in the maximum velocity of myocardial contraction during
the systole with left-sided SGB.
Conclusions: Even with our methods we could not prevent the simultaneous occurrence of a partial
parasympatholytic effect. For this reason, the SGB has only minor hemodynamic effects, which is desirable as it
enhances the safety of the SGB.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Medical Education > Institute of Complementary and Integrative Medicine (IKIM)

UniBE Contributor:

Puente de la Vega Costa, Katia Pilar, Fischer, Lorenz


600 Technology > 610 Medicine & health








Lorenz Fischer

Date Deposited:

24 May 2017 11:23

Last Modified:

05 Apr 2023 10:21

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

Echocardiographic parameters; Hemodynamic parameters; Local anesthesia; Neural therapy; Procaine; Stellate ganglion block





Actions (login required)

Edit item Edit item
Provide Feedback