Deletion in the gene BruAb2_0168 of Brucella abortus strains: diagnostic challenges.

Dean, A S; Schelling, E; Bonfoh, B; Kulo, A E; Boukaya, G A; Pilo, Paola (2014). Deletion in the gene BruAb2_0168 of Brucella abortus strains: diagnostic challenges. Clinical microbiology and infection, 20(9), O550-O553. Blackwell Publishing 10.1111/1469-0691.12554

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Three Brucella abortus strains were isolated from joint hygromas from cows in northern Togo. Two deletions in the 5' side of the gene BruAb2_0168 were identified. As this gene is used for species identification, these deletions have consequences for diagnostic procedures. Multiple locus variable number of tandem repeat (VNTR) analysis was therefore performed for species identification. The strains showed unique VNTR profiles, providing some of the first genotypic data from West Africa. More molecular and epidemiological data are needed from the region, in order to better understand transmission patterns and develop suitable diagnostic assays.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Veterinary Bacteriology

UniBE Contributor:

Pilo, Paola

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 630 Agriculture

ISSN:

1198-743X

Publisher:

Blackwell Publishing

Language:

English

Submitter:

Paola Pilo

Date Deposited:

14 Aug 2017 15:34

Last Modified:

14 Aug 2017 15:34

Publisher DOI:

10.1111/1469-0691.12554

PubMed ID:

24450581

Uncontrolled Keywords:

Brucella; Togo; cattle; diagnostics; genotyping

BORIS DOI:

10.7892/boris.99345

URI:

https://boris.unibe.ch/id/eprint/99345

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