Koch, A; Völzke, A; Wünsche, C; Meyer zu Heringdorf, D; Huwiler, A; Pfeilschifter, J (2012). Thiazolidinedione-dependent activation of sphingosine kinase 1 causes an anti-fibrotic effect in renal mesangial cells. British journal of pharmacology, 166(3), pp. 1018-32. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2012.01824.x
Full text not available from this repository.PPARγ agonists [thiazolidinediones (TZDs)] are known to exert anti-fibrotic effects in the kidney. In addition, we previously demonstrated that sphingosine kinase 1 (SK-1) and intracellular sphingosine-1-phosphate (S1P), by reducing the expression of connective tissue growth factor (CTGF), have a protective role in the fibrotic process.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Pharmacology |
UniBE Contributor: |
Huwiler, Andrea |
ISSN: |
0007-1188 |
Publisher: |
Wiley-Blackwell |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:35 |
Last Modified: |
05 Dec 2022 14:11 |
Publisher DOI: |
10.1111/j.1476-5381.2012.01824.x |
PubMed ID: |
22221312 |
Web of Science ID: |
000303923000017 |
URI: |
https://boris.unibe.ch/id/eprint/14088 (FactScience: 220895) |
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