Probing the relevance of carbene binding motifs in enzyme reactivity

Commencement Date / Completion DateUNSPECIFIED - UNSPECIFIED
Funders [18] European Research Council
Publications Wei, Yingfei; Liu, Shi-Xia; Müller-Bunz, Helge; Albrecht, Martin (2016). Synthesis of Triazolylidene Nickel Complexes and Their Catalytic Application in Selective Aldehyde Hydrosilylation. ACS Catalysis, 6(12), pp. 8192-8200. American Chemical Society 10.1021/acscatal.6b02269
Schmitt, Florian; Donnelly, Kate; Muenzner, Julienne K.; Rehm, Tobias; Novohradsky, Vojtech; Brabec, Viktor; Kasparkova, Jana; Albrecht, Martin; Schobert, Rainer; Mueller, Thomas (2016). Effects of histidin-2-ylidene vs. imidazol-2-ylidene ligands on the anticancer and antivascular activity of complexes of ruthenium, iridium, platinum, and gold. Journal of inorganic biochemistry, 163, pp. 221-228. Elsevier 10.1016/j.jinorgbio.2016.07.021
Planchestainer, Matteo; Ségaud, Nathalie Sylvie Laetitia; Shanmugam, Muralidharan; McMaster, Jonathan; Paradisi, Francesca; Albrecht, Martin (2018). Carbene in Cupredoxin Protein Scaffolds: Replacement of a Histidine Ligand in the Active Site Substantially Alters Copper Redox Properties. Angewandte Chemie (International ed.), 57(33), pp. 10677-10682. Wiley-VCH 10.1002/anie.201807168

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