Althaus, Christian

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Keiser, Olivia; Agoritsas, Thomas; Althaus, Christian L; Azman, Andrew S; de Quervain, Dominique; Flahault, Antoine; Goutaki, Myrofora; Merglen, Arnaud; Eckerle, Isabella (2021). A public health strategy for SARS-CoV-2, grounded in science, should guide Swiss schools through the coming winter [viewpoint]. Swiss medical weekly, 151, w30086. EMH Schweizerischer Ärzteverlag 10.4414/smw.2021.w30086

Riou, Julien; Dupont, Carole; Bertagnolio, Silvia; Gupta, Ravindra K; Kouyos, Roger D; Egger, Matthias; Althaus, Christian L. (2021). Drivers of HIV-1 drug resistance to non-nucleoside reverse-transcriptase inhibitors (NNRTIs) in nine southern African countries: a modelling study. BMC infectious diseases, 21(1), p. 1042. BioMed Central 10.1186/s12879-021-06757-6

Riou, Julien; Panczak, Radoslaw; Althaus, Christian L; Junker, Christoph; Perisa, Damir; Schneider, Katrin; Criscuolo, Nicola G; Low, Nicola; Egger, Matthias (2021). Socioeconomic position and the COVID-19 care cascade from testing to mortality in Switzerland: a population-based analysis. The lancet. Public health, 6(9), e683-e691. Elsevier 10.1016/S2468-2667(21)00160-2

Chen, Chaoran; Nadeau, Sarah Ann; Topolsky, Ivan; Manceau, Marc; Huisman, Jana S; Jablonski, Kim Philipp; Fuhrmann, Lara; Dreifuss, David; Jahn, Katharina; Beckmann, Christiane; Redondo, Maurice; Noppen, Christoph; Risch, Lorenz; Risch, Martin; Wohlwend, Nadia; Kas, Sinem; Bodmer, Thomas; Roloff, Tim; Stange, Madlen; Egli, Adrian; ... (2021). Quantification of the spread of SARS-CoV-2 variant B.1.1.7 in Switzerland. (In Press). Epidemics, 37, p. 100480. Elsevier 10.1016/j.epidem.2021.100480

Kremer, Cécile; Torneri, Andrea; Boesmans, Sien; Meuwissen, Hanne; Verdonschot, Selina; Vanden Driessche, Koen; Althaus, Christian L.; Faes, Christel; Hens, Niel (2021). Quantifying superspreading for COVID-19 using Poisson mixture distributions. Scientific reports, 11(1), p. 14107. Springer Nature 10.1038/s41598-021-93578-x

Hodcroft, Emma B.; Zuber, Moira; Nadeau, Sarah; Vaughan, Timothy G; Crawford, Katharine H D; Althaus, Christian L.; Reichmuth, Martina L.; Bowen, John E; Walls, Alexandra C; Corti, Davide; Bloom, Jesse D; Veesler, David; Mateo, David; Hernando, Alberto; Comas, Iñaki; Candelas, Fernando González; Stadler, Tanja; Neher, Richard A (2021). Spread of a SARS-CoV-2 variant through Europe in the summer of 2020. Nature, 595(7869), pp. 707-712. Macmillan Journals Ltd. 10.1038/s41586-021-03677-y

Menges, Dominik; Aschmann, Hélène E; Moser, André; Althaus, Christian L.; von Wyl, Viktor (2021). A Data-Driven Simulation of the Exposure Notification Cascade for Digital Contact Tracing of SARS-CoV-2 in Zurich, Switzerland. JAMA Network Open, 4(4), e218184. American Medical Association 10.1001/jamanetworkopen.2021.8184


Salathé, Marcel; Althaus, Christian L; Anderegg, Nanina; Antonioli, Daniele; Ballouz, Tala; Bugnon, Edouard; Čapkun, Srdjan; Jackson, Dennis; Kim, Sang-Il; Larus, Jim; Low, Nicola; Lueks, Wouter; Menges, Dominik; Moullet, Cédric; Payer, Mathias; Riou, Julien; Stadler, Theresa; Troncoso, Carmela; Vayena, Effy and von Wyl, Viktor (2020). Early evidence of effectiveness of digital contact tracing for SARS-CoV-2 in Switzerland. Swiss medical weekly, 150, w20457. EMH Schweizerischer Ärzteverlag 10.4414/smw.2020.20457

Heng, Kevin; Althaus, Christian L (2020). The approximately universal shapes of epidemic curves in the Susceptible-Exposed-Infectious-Recovered (SEIR) model. Scientific Reports, 10(1), p. 19365. Nature Publishing Group 10.1038/s41598-020-76563-8

Smid, Joost H; Althaus, Christian L; Low, Nicola; Unemo, Magnus; Herrmann, Bjőrn (2020). Rise and fall of the new variant of Chlamydia trachomatis in Sweden: mathematical modelling study. Sexually transmitted infections, 96(5), pp. 375-379. BMJ Publishing Group 10.1136/sextrans-2019-054057

Hauser, Anthony; Counotte, Michel J.; Margossian, Charles C; Konstantinoudis, Garyfallos; Low, Nicola; Althaus, Christian L.; Riou, Julien (2020). Estimation of SARS-CoV-2 mortality during the early stages of an epidemic: A modeling study in Hubei, China, and six regions in Europe. PLoS medicine, 17(7), e1003189. Public Library of Science 10.1371/journal.pmed.1003189

Ashcroft, Peter; Huisman, Jana S; Lehtinen, Sonja; Bouman, Judith A; Althaus, Christian L.; Regoes, Roland R; Bonhoeffer, Sebastian (2020). COVID-19 infectivity profile correction [viewpoint]. Swiss medical weekly, 150, w20336. EMH Schweizerischer Ärzteverlag 10.4414/smw.2020.20336

Chowdhury, Rajiv; Heng, Kevin; Shawon, Md Shajedur Rahman; Goh, Gabriel; Okonofua, Daisy; Ochoa-Rosales, Carolina; Gonzalez-Jaramillo, Valentina; Bhuiya, Abbas; Reidpath, Daniel; Prathapan, Shamini; Shahzad, Sara; Althaus, Christian L.; Gonzalez-Jaramillo, Nathalia; Franco, Oscar H. (2020). Dynamic interventions to control COVID-19 pandemic: a multivariate prediction modelling study comparing 16 worldwide countries. European journal of epidemiology, 35(5), pp. 389-399. Springer 10.1007/s10654-020-00649-w

Cadosch, Dominique; Garcia, Victor; Jensen, Jørgen S; Low, Nicola; Althaus, Christian L. (2020). Understanding the spread of de novo and transmitted macrolide-resistance in Mycoplasma genitalium. PeerJ, 8, e8913. PeerJ, Ltd 10.7717/peerj.8913

Estcourt, Claudia S; Howarth, Alison R; Copas, Andrew; Low, Nicola; Mapp, Fiona; Woode Owusu, Melvina; Flowers, Paul; Roberts, Tracy; Mercer, Catherine H; Wayal, Sonali; Symonds, Merle; Nandwani, Rak; Saunders, John; Johnson, Anne M; Pothoulaki, Maria; Althaus, Christian; Pickering, Karen; McKinnon, Tamsin; Brice, Susannah; Comer, Alex; ... (2020). Accelerated partner therapy (APT) partner notification for people with Chlamydia trachomatis: protocol for the Limiting Undetected Sexually Transmitted infections to RedUce Morbidity (LUSTRUM) APT cross-over cluster randomised controlled trial. BMJ open, 10(3), e034806. BMJ Publishing Group 10.1136/bmjopen-2019-034806

Salathé, Marcel; Althaus, Christian L; Neher, Richard; Stringhini, Silvia; Hodcroft, Emma; Fellay, Jacques; Zwahlen, Marcel; Senti, Gabriela; Battegay, Manuel; Wilder-Smith, Annelies; Eckerle, Isabella; Egger, Matthias; Low, Nicola (2020). COVID-19 epidemic in Switzerland: on the importance of testing, contact tracing and isolation. Swiss medical weekly, 150, w20225. EMH Media 10.4414/smw.2020.20225

Brugger, Jon; Althaus, Christian L. (2020). Transmission of and susceptibility to seasonal influenza in Switzerland from 2003 to 2015. Epidemics, 30, p. 100373. Elsevier 10.1016/j.epidem.2019.100373

Riou, Julien; Althaus, Christian L (2020). Pattern of early human-to-human transmission of Wuhan 2019 novel coronavirus (2019-nCoV), December 2019 to January 2020. Eurosurveillance, 25(4), pii=2000058. European Centre for Disease Prevention and Control 10.2807/1560-7917.ES.2020.25.4.2000058

Gsteiger, Sandro; Low, Nicola; Sonnenberg, Pam; Mercer, Catherine H; Althaus, Christian L (2020). Gini coefficients for measuring the distribution of sexually transmitted infections among individuals with different levels of sexual activity. PeerJ, 8, e8434. PeerJ, Ltd 10.7717/peerj.8434


Counotte, Michel J; Althaus, Christian L; Low, Nicola; Riou, Julien (2019). Impact of age-specific immunity on the timing and burden of the next Zika virus outbreak. PLoS neglected tropical diseases, 13(12), e0007978. Public Library of Science 10.1371/journal.pntd.0007978

Smid, Joost; Althaus, Christian; Low, Nicola (2019). Discrepancies between observed data and predictions from mathematical modelling of the impact of screening interventions on Chlamydia trachomatis prevalence. Scientific Reports, 9(1), p. 7547. Nature Publishing Group 10.1038/s41598-019-44003-x

Omori, Ryosuke; Chemaitelly, Hiam; Althaus, Christian L; Abu-Raddad, Laith J (2019). Does infection with Chlamydia trachomatis induce long-lasting partial immunity? Insights from mathematical modelling. Sexually transmitted infections, 95(2), pp. 115-121. BMJ Publishing Group 10.1136/sextrans-2018-053543

Porgo, Teegwendé V; Norris, Susan L; Salanti, Georgia; Johnson, Leigh F; Simpson, Julie A; Low, Nicola; Egger, Matthias; Althaus, Christian L (2019). The use of mathematical modelling studies for evidence synthesis and guideline development: a glossary. Research Synthesis Methods, 10(1), pp. 125-133. Wiley 10.1002/jrsm.1333


Smid, Joost H; Garcia, Victor; Low, Nicola; Mercer, Catherine H; Althaus, Christian L (2018). Age difference between heterosexual partners in Britain: Implications for the spread of Chlamydia trachomatis. Epidemics, 24, pp. 60-66. Elsevier 10.1016/j.epidem.2018.03.004

Riesen, Maurane; Konstantinoudis, Garyfallos; Lang, Phung; Low, Nicola; Hatz, Christoph; Maeusezahl, Mirjam; Spaar, Anne; Bühlmann, Marc; Spycher, Ben D; Althaus, Christian L (2018). Exploring variation in human papillomavirus vaccination uptake in Switzerland: a multilevel spatial analysis of a national vaccination coverage survey. BMJ open, 8(5), e021006. BMJ Publishing Group 10.1136/bmjopen-2017-021006

Egger, Matthias; Johnson, Leigh; Althaus, Christian; Schöni, Anna; Salanti, Georgia; Low, Nicola; Norris, Susan L (2018). Developing WHO guidelines: Time to formally include evidence from mathematical modelling studies [version 2; referees: 2 approved]. F1000Research, 6, p. 1584. F1000 Research Ltd 10.12688/f1000research.12367.2


Riesen, Maurane; Garcia, Victor; Low, Nicola; Althaus, Christian L (2017). Modeling the consequences of regional heterogeneity in human papillomavirus (HPV) vaccination uptake on transmission in Switzerland. Vaccine, 35(52), pp. 7312-7321. Elsevier 10.1016/j.vaccine.2017.10.103

Unemo, Magnus; Althaus, Christian L (2017). Fitness cost and benefit of antimicrobial resistance in Neisseria gonorrhoeae: Multidisciplinary approaches are needed. PLoS medicine, 14(10), e1002423. Public Library of Science 10.1371/journal.pmed.1002423

Egger, Matthias; Johnson, Leigh; Althaus, Christian; Schöni, Anna; Salanti, Georgia; Low, Nicola; Norris, Susan L. (2017). Developing WHO guidelines: Time to formally include evidence from mathematical modelling studies [version 1; referees: 1 approved]. F1000Research, 6(1584) F1000 Research Ltd 10.12688/f1000research.12367.1

Fingerhuth, Stephanie M.; Low, Nicola; Bonhoeffer, Sebastian; Althaus, Christian L. (2017). Detection of antibiotic resistance is essential for gonorrhoea point-of-care testing: a mathematical modelling study. BMC medicine, 15(1), p. 142. BioMed Central 10.1186/s12916-017-0881-x

Foerster, Sunniva; Desilvestro, Valentino; Hathaway, Lucy J; Althaus, Christian L; Unemo, Magnus (2017). A new rapid resazurin-based microdilution assay for antimicrobial susceptibility testing of Neisseria gonorrhoeae. Journal of antimicrobial chemotherapy, 72(7), pp. 1961-1968. Oxford University Press 10.1093/jac/dkx113

Smid, JH; Garcia, V; Mercer, CH; Low, N; Althaus, CL (2017). P3.209 Age differences between heterosexual partners: implications for the spread of chlamydia trachomatis. Sexually transmitted infections, 39(Suppl 2), A171.1-A171. BMJ Publishing Group 10.1136/sextrans-2017-053264.444

Fingerhuth, Stephanie M; Low, Nicola; Bonhoeffer, Sebastian; Althaus, Christian L (2017). P3.212 Antibiotic resistance detection is essential for gonorrhoea point-of-care testing: a mathematical modelling study. Sexually transmitted infections, 39(Suppl 2), A172.1-A172. BMJ Publishing Group 10.1136/sextrans-2017-053264.447


Althaus, Christian L; Low, Nicola (2016). How Relevant Is Sexual Transmission of Zika Virus? PLoS medicine, 13(10), e1002157. Public Library of Science 10.1371/journal.pmed.1002157

Althaus, Christian L (2016). Modeling the Ebola epidemic : challenges and lessons for the future. In: Evans, Nicholas G.; Smith, Tara C.; Majumder, Maiuma S. (eds.) Ebola's Message. Public Health and Medicine in the Twenty-First Century (pp. 47-60). Cambridge (Mass.): The MIT Press

Krauer, Fabienne; Gsteiger, Sandro; Low, Nicola; Hansen, Christian H; Althaus, Christian L (2016). Heterogeneity in District-Level Transmission of Ebola Virus Disease during the 2013-2015 Epidemic in West Africa. PLoS neglected tropical diseases, 10(7), e0004867. Public Library of Science 10.1371/journal.pntd.0004867

Fingerhuth, Stephanie M; Bonhoeffer, Sebastian; Low, Nicola; Althaus, Christian L (2016). Antibiotic-Resistant Neisseria gonorrhoeae Spread Faster with More Treatment, Not More Sexual Partners. PLoS pathogens, 12(5), e1005611. Public Library of Science 10.1371/journal.ppat.1005611

Abbate, Jessica L; Murall, Carmen Lia; Richner, Heinz; Althaus, Christian L (2016). Potential Impact of Sexual Transmission on Ebola Virus Epidemiology: Sierra Leone as a Case Study. PLoS neglected tropical diseases, 10(5), e0004676. Public Library of Science 10.1371/journal.pntd.0004676

Förster, Sunniva; Unemo, Magnus; Hathaway, Lucy J.; Low, Nicola; Althaus, Christian L. (2016). Time-kill curve analysis and pharmacodynamic modelling for in vitro evaluation of antimicrobials against Neisseria gonorrhoeae. BMC microbiology, 16, p. 216. BioMed Central 10.1186/s12866-016-0838-9


Foerster, Sunniva; Golparian, Daniel; Jacobsson, Susanne; Hathaway, Lucy J; Low, Nicola; Shafer, William M; Althaus, Christian L; Unemo, Magnus (2015). Genetic Resistance Determinants, In Vitro Time-Kill Curve Analysis and Pharmacodynamic Functions for the Novel Topoisomerase II Inhibitor ETX0914 (AZD0914) in Neisseria gonorrhoeae. Frontiers in Microbiology, 6, p. 1377. Frontiers 10.3389/fmicb.2015.01377

Althaus, Christian L (2015). Rapid drop in the reproduction number during the Ebola outbreak in the Democratic Republic of Congo. PeerJ, 3, e1418. PeerJ, Ltd 10.7717/peerj.1418

Althaus, Christian; Salathé, Marcel (2015). Measles Vaccination Coverage and Cases among Vaccinated Persons. Emerging infectious diseases, 21(8), pp. 1480-1481. U.S. National Center for Infectious Diseases 10.3201/eid2108.150284

Kucharski, A J; Althaus, C L (2015). The role of superspreading in Middle East respiratory syndrome coronavirus (MERS-CoV) transmission. Euro surveillance, 20(25), pii=21167. Institut de Veille Sanitaire

Althaus, C L; Low, N; Musa, E O; Shuaib, F; Gsteiger, S (2015). Ebola virus disease outbreak in Nigeria: Transmission dynamics and rapid control. Epidemics, 11, pp. 80-84. Elsevier 10.1016/j.epidem.2015.03.001

Althaus, Christian (2015). Ebola superspreading. Lancet infectious diseases, 15(5), pp. 507-508. Elsevier 10.1016/S1473-3099(15)70135-0

Althaus, Christian L (2015). Of mice, macaques and men: scaling of virus dynamics and immune responses. Frontiers in Microbiology, 6, p. 355. Frontiers 10.3389/fmicb.2015.00355


Althaus, Christian L.; Joos, Beda; Perelson, Alan S.; Günthard, Huldrych F. (2014). Quantifying the turnover of transcriptional subclasses of HIV-1-infected cells. PLoS computational biology, 10(10), e1003871. Public Library of Science 10.1371/journal.pcbi.1003871

Althaus, Christian L (2014). Estimating the Reproduction Number of Ebola Virus (EBOV) During the 2014 Outbreak in West Africa. PLoS currents, 6(version 1) Public Library of Science 10.1371/currents.outbreaks.91afb5e0f279e7f29e7056095255b288

Low, Nicola; Heijne, Janneke Cornelia Maria; Herzog, Sereina Annik; Althaus, Christian Lorenz (2014). Reinfection by untreated partners of people treated for Chlamydia trachomatis and Neisseria gonorrhoeae: mathematical modelling study. Sexually transmitted infections, 90(3), pp. 254-6. BMJ Publishing Group 10.1136/sextrans-2013-051279

Althaus, Christian L.; Turner, Katherine ME; Mercer, Catherine H.; Auguste, Peter; Roberts, Tracy E.; Bell, Gill; Herzog, Sereina A.; Cassell, Jackie A.; Edmunds, W. John; White, Peter J.; Ward, Helen; Low, Nicola (2014). Effectiveness and cost-effectiveness of traditional and new partner notification technologies for curable sexually transmitted infections: observational study, systematic reviews and mathematical modelling. Health technology assessment, 18(2), pp. 1-100. National Coordinating Centre for Health Technology Assessment 10.3310/hta18020


Herzog, Sereina A.; Heijne, Janneke C. M.; Scott, Pippa; Althaus, Christian L.; Low, Nicola (2013). Direct and indirect effects of screening for Chlamydia trachomatis on the prevention of pelvic inflammatory disease: a mathematical modeling study. EPIDEMIOLOGY, 24(6), pp. 854-862. Lippincott Williams & Wilkins 10.1097/EDE.0b013e31829e110e

Heijne, Janneke C. M.; Herzog, Sereina A.; Althaus, Christian L.; Low, Nicola; Kretzschmar, Mirjam (2013). Case and partnership reproduction numbers for a curable sexually transmitted infection. JOURNAL OF THEORETICAL BIOLOGY, 331, pp. 38-47. Elsevier 10.1016/j.jtbi.2013.04.010

Heijne, Janneke Cornelia Maria; Herzog, Sereina Annik; Althaus, Christian Lorenz; Tao, Guoyu; Kent, Charlotte Kathleen; Low, Nicola (2013). Insights into the timing of repeated testing after treatment for Chlamydia trachomatis: data and modelling study. Sexually transmitted infections, 89(1), pp. 57-62. London: BMJ Publishing Group 10.1136/sextrans-2011-050468


Althaus, Christian L.; Heijne, Janneke C. M.; Low, Nicola (2012). Towards More Robust Estimates of the Transmissibility of Chlamydia trachomatis. Sexually transmitted diseases, 39(5), pp. 402-404. Philadelphia, Pa.: Lippincott Williams & Wilkins 10.1097/OLQ.0b013e318248a550

Althaus, Christian L; Turner, Katherine M E; Schmid, Boris V; Heijne, Janneke C M; Kretzschmar, Mirjam; Low, Nicola (2012). Transmission of Chlamydia trachomatis through sexual partnerships: a comparison between three individual-based models and empirical data. Interface - journal of the Royal Society, 9(66), pp. 136-46. London: The Royal Society 10.1098/rsif.2011.0131

Althaus, Christian L.; Heijne, Janneke C. M.; Herzog, Sereina A; Roellin, Adrian; Low, Nicola (2012). Individual and population level effects of partner notification for Chlamydia trachomatis. PLoS ONE, 7(12), e51438. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0051438

Herzog, Sereina A; Althaus, Christian L; Heijne, Janneke Cm; Oakeshott, Pippa; Kerry, Sally; Hay, Phillip; Low, Nicola (2012). Timing of progression from Chlamydia trachomatis infection to pelvic inflammatory disease: a mathematical modelling study. BMC infectious diseases, 12, p. 187. London: BioMed Central 10.1186/1471-2334-12-187

Herzog, Sereina A; Heijne, Janneke C M; Althaus, Christian L; Low, Nicola (2012). Describing the progression from Chlamydia trachomatis and Neisseria gonorrhoeae to pelvic inflammatory disease: systematic review of mathematical modeling studies. Sexually transmitted diseases, 39(8), pp. 628-37. Philadelphia, Pa.: Lippincott Williams & Wilkins 10.1097/OLQ.0b013e31825159ff

Althaus, Christian; De Boer, Rob J (2012). Impaired immune evasion in HIV through intracellular delays and multiple infection of cells. Proceedings of the Royal Society. Series B - biological sciences, 279(1740), pp. 3003-10. London: Royal Society of London 10.1098/rspb.2012.0328


Heijne, Janneke C M; Althaus, Christian L; Herzog, Sereina A; Kretzschmar, Mirjam; Low, Nicola (2011). The role of reinfection and partner notification in the efficacy of Chlamydia screening programs. Journal of infectious diseases, 203(3), pp. 372-377. Cary, N.C.: Oxford University Press 10.1093/infdis/jiq050

Althaus, Christian L.; De Boer, Rob J.; Dieli, Francesco (2011). Implications of CTL-Mediated Killing of HIV-Infected Cells during the Non-Productive Stage of Infection. PLoS ONE, 6(2), e16468. Public Library of Science 10.1371/journal.pone.0016468


Althaus, Christian L.; Heijne, Janneke C.M.; Röllin, Adrian; Low, Nicola (2010). Transmission dynamics of Chlamydia trachomatis affect the impact of screening programmes. Epidemics, 2(3), pp. 123-131. Amsterdam: Elsevier 10.1016/j.epidem.2010.04.002


Althaus, Christian L.; De Boer, Rob J.; Pascual, Mercedes (2008). Dynamics of Immune Escape during HIV/SIV Infection. PLoS computational biology, 4(7), e1000103. Public Library of Science 10.1371/journal.pcbi.1000103

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