Baur, Roland

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Borgström, Anna; Hauert, Barbara; Kappel, Sven; Zoni, Eugenio; Kiener, Mirjam; Stokłosa, Paulina; Baur, Roland; Spahn, Martin; Kruithof-de Julio, Marianna; Peinelt, Christine (2020). Small Molecular Inhibitors Block TRPM4 Currents in Prostate Cancer Cells, with Limited Impact on Cancer Hallmark Functions. (In Press). Journal of molecular biology, p. 166665. Elsevier 10.1016/j.jmb.2020.09.024

Schild, Achille; Bhardwaj, Rajesh; Wenger, Nicolas; Tscherrig, Dominic; Kandasamy, Palanivel; Dernič, Jan; Baur, Roland; Peinelt, Christine; Hediger, Matthias A.; Lochner, Martin (2020). Synthesis and Pharmacological Characterization of 2-Aminoethyl Diphenylborinate (2-APB) Derivatives for Inhibition of Store-Operated Calcium Entry (SOCE) in MDA-MB-231 Breast Cancer Cells. International journal of molecular sciences, 21(16) Molecular Diversity Preservation International MDPI 10.3390/ijms21165604

Kappel, Sven; Kilch, Tatiana; Baur, Roland; Lochner, Martin; Peinelt, Christine (2020). The Number and Position of Orai3 Units within Heteromeric Store-Operated Ca2+ Channels Alter the Pharmacology of ICRAC. International Journal of Molecular Sciences, 21(7) MDPI 10.3390/ijms21072458

Kappel, Sven; Stoklosa, Paulina; Hauert, Barbara; Ross-Kaschitza, Daniela; Borgström, Anna; Baur, Roland; Galván, José A.; Zlobec, Inti; Peinelt, Christine (2019). TRPM4 is highly expressed in human colorectal tumor buds and contributes to proliferation, cell cycle, and invasion of colorectal cancer cells. Molecular oncology, 13(11), pp. 2393-2405. FEBS Press 10.1002/1878-0261.12566

Wongsamitkul, Nisa; Maldifassi, Maria Constanza; Simeone, Xenia Maria Laura; Baur, Roland; Ernst, Margot; Sigel, Erwin (2017). α subunits in GABAA receptors are dispensable for GABA and diazepam action. Scientific Reports, 7(1), p. 15498. Nature Publishing Group 10.1038/s41598-017-15628-7

Baur, Roland; Sigel, Erwin (2017). Low Expression in Xenopus Oocytes and Unusual Functional Properties of α1β2γ2 GABAA Receptors with Non-Conventional Subunit Arrangement. PLoS ONE, 12(1), e0170572. Public Library of Science 10.1371/journal.pone.0170572

Maldifassi, Maria Constanza; Wongsamitkul, Nisa; Baur, Roland; Sigel, Erwin (2016). Xenopus Oocytes: Optimized Methods for Microinjection, Removal of Follicular Cell Layers, and Fast Solution Changes in Electrophysiological Experiments. Journal of visualized experiments(118) MYJoVE Corporation 10.3791/55034

Maldifassi, Maria Constanza; Baur, Roland; Sigel, Erwin (2016). Molecular mode of action of CGS 9895 at α1 β2 γ2 GABAA receptors. Journal of neurochemistry, 138(5), pp. 722-730. Wiley 10.1111/jnc.13711

Wongsamitkul, Nisa; Baur, Roland; Sigel, Erwin (2016). Toward Understanding Functional Properties and Subunit Arrangement of α4β2δ γ-Aminobutyric Acid, Type A (GABAA) Receptors. Journal of biological chemistry, 291(35), pp. 18474-18483. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M116.738906

Maldifassi, Maria Constanza; Baur, Roland; Pierce, David; Nourmahnad, Anahita; Forman, Stuart A; Sigel, Erwin (2016). Novel positive allosteric modulators of GABAA receptors with anesthetic activity. Scientific Reports, 6(25943), p. 25943. Nature Publishing Group 10.1038/srep25943

Crockett, Sara; Baur, Roland; Kunert, Olaf; Belaj, Ferdinand; Sigel, Erwin (2016). A new chromanone derivative isolated from Hypericum lissophloeus (Hypericaceae) potentiates GABAA receptor currents in a subunit specific fashion. Bioorganic & medicinal chemistry, 24(4), pp. 681-685. Elsevier 10.1016/j.bmc.2015.12.037

Maldifassi, Maria Constanza; Baur, Roland; Sigel, Erwin (2016). Functional sites involved in modulation of the GABAA receptor channel by the intravenous anesthetics propofol, etomidate and pentobarbital. Neuropharmacology, 105, pp. 207-214. Elsevier 10.1016/j.neuropharm.2016.01.003

Middendorp, Simon; Maldifassi, Maria Constanza; Baur, Roland; Sigel, Erwin (2015). Positive modulation of synaptic and extrasynaptic GABAA receptors by an antagonist of the high affinity benzodiazepine binding site. Neuropharmacology, 95, pp. 459-467. Elsevier 10.1016/j.neuropharm.2015.04.027

Baur, Roland; Beech, Robin; Sigel, Erwin; Rufener, Lucien (2015). Monepantel irreversibly binds to and opens Haemonchus contortus MPTL-1 and Caenorhabditis elegans ACR-20 receptors. Molecular pharmacology, 87(1), pp. 96-102. American Society for Pharmacology and Experimental Therapeutics 10.1124/mol.114.095653

Fedurco, Milan; Gregorová, Jana; Šebrlová, Kristýna; Kantorová, Jana; Peš, Ondřej; Baur, Roland; Sigel, Erwin; Táborská, Eva (2015). Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors. Biochemistry research international, 2015(617620), p. 617620. Hindawi Publishing Corporation 10.1155/2015/617620

Fuchs, Alexander; Baur, Roland; Schoeder, Clara; Sigel, Erwin; Müller, Christa E (2014). Structural analogues of the natural products magnolol and honokiol as potent allosteric potentiators of GABA(A) receptors. Bioorganic & medicinal chemistry, 22(24), pp. 6908-6917. Elsevier 10.1016/j.bmc.2014.10.027

Baur, Roland; Schuehly, Wolfgang; Sigel, Erwin (2014). Moderate concentrations of 4-O-methylhonokiol potentiate GABAA receptor currents stronger than honokiol. Biochimica et biophysica acta (BBA) - general subjects, 1840(10), pp. 3017-3021. Elsevier 10.1016/j.bbagen.2014.06.016

Middendorp, Simon; Puthenkalam, Roshan; Baur, Roland; Ernst, Margot; Sigel, Erwin (2014). Accelerated discovery of novel benzodiazepine ligands by experiment-guided virtual screening. ACS Chemical Biology, 9(8), pp. 1854-1859. American Chemical Society 10.1021/cb5001873

Carta, Valentina; Pangerl, Michael; Baur, Roland; Puthenkalam, Roshan; Ernst, Margot; Trauner, Dirk; Sigel, Erwin (2014). A pentasymmetric open channel blocker for Cys-loop receptor channels. PLoS ONE, 9(9), e106688. Public Library of Science 10.1371/journal.pone.0106688

Baur, Roland; Gertsch, Jürg; Sigel, Erwin (2013). Do N-arachidonyl-glycine (NA-glycine) and 2-arachidonoyl glycerol (2-AG) share mode of action and the binding site on the β 2 subunit of GABA A receptors? PeerJ, 1, e149. PeerJ, Ltd 10.7717/peerj.149

Rufener, Lucien; Bedoni, Nicola; Baur, Roland; Rey, Samantha; Glauser, Dominique A.; Bouvier, Jacques; Beech, Robin; Sigel, Erwin; Puoti, Alessandro (2013). acr-23 Encodes a Monepantel-Sensitive Channel in Caenorhabditis elegans. PLoS pathogens, 9(8), e1003524. Public Library of Science 10.1371/journal.ppat.1003524

Baur, Roland; Kielar, Marie; Richter, Lars; Ernst, Margot; Ecker, Gerhard F.; Sigel, Erwin (2013). Molecular analysis of the site for 2-arachidonylglycerol (2-AG) on the β 2 subunit of GABA A receptors. Journal of neurochemistry, 126(1), pp. 29-36. Wiley-Blackwell 10.1111/jnc.12270

Lüscher, Benjamin P; Baur, Roland; Goeldner, Maurice; Sigel, Erwin (2012). Influence of GABA(A) receptor α subunit isoforms on the benzodiazepine binding site. PLoS ONE, 7(7), e42101. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0042101

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