Frauchiger, Daniela Angelika

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2018

Frauchiger, Daniela Angelika; Chan, Samantha; Benneker, Lorin Michael; Gantenbein, Benjamin (2018). Intervertebral disc damage models in organ culture: a comparison of annulus fibrosus cross-incision versus punch model under complex loading. European spine journal, 27(8), pp. 1785-1797. Springer 10.1007/s00586-018-5638-5

Frauchiger, Daniela Angelika; Tekari, Adel; Wöltje, M; Benneker, Lorin Michael; Gantenbein, Benjamin (8 July 2018). Mechanical loading of genipin-enhanced fibrin hydrogel combined with engineered silk composite for intervertebral disc repair (Unpublished). In: Proceedings of the 8th World Conference of Biomechanics, 8-12 July.

Frauchiger, Daniela Angelika; Chan, Samantha; Benneker, Lorin Michael; Gantenbein, Benjamin (25 June 2018). Comparison of two annulus fibrosus injury models investigated in a loaded bovine intervertebral disc organ culture format. eCM online periodical, Collection 3, P15-P15. AO Foundation

May, Rahel Deborah; Rodrigues Sousa, Elisa; Frauchiger, Daniela Angelika; Albers, Christoph; Benneker, Lorin Michael; Gantenbein, Benjamin (25 June 2018). Osteoinductive stimulation of intervertebral disc cells with bone morphogenetic protein 2 or osteogenic medium. eCM online periodical, Collection 3, P33-P33. AO Foundation

Frauchiger, Daniela Angelika; May, Rahel Deborah; Zhang, Xingshuo; Stoyanov, J; Bertolo, A; Benneker, Lorin Michael; Grad, S; Tryfonidou, M; Gantenbein, Benjamin (25 June 2018). Comparing three cell isolation techniques for fishing angiopoetin-1 (Tie 2) positive progenitor cells from the nucleus pulposus. eCM online periodical, Collection 3, P17-P17. AO Foundation

Frauchiger, Daniela Angelika; May, Rahel Deborah; Bakirci, Ezgi; Wöltje, M; Benneker, Lorin Michael; Gantenbein, Benjamin (25 June 2018). Annulus fibrosus repair approach combining genipin-enhanced fibrin hydrogel and engineered silk fleece-membrane composite. eCM online periodical, Collection 3, P16-P16. AO Foundation

Frauchiger, Daniela Angelika; May, Rahel Deborah; Wöltje, M; Benneker, Lorin Michael; Gantenbein, Benjamin (6 June 2018). Genipin-enhanced fibrin hydrogel combined with engineered silk composite for intervertebral disc repair. eCM online periodical, Collection 2, p. 6. AO Foundation

May, Rahel Deborah; Frauchiger, Daniela Angelika; Albers, Christoph; Benneker, Lorin Michael; Gantenbein, Benjamin (6 June 2018). The influence of primary human intervertebral disc cells on primary human osteoblasts. eCM online periodical, Collection 2, p. 16. AO Foundation

Sakai, D.; Schol, J.; Bach, F. C.; Tekari, A.; Sagawa, N.; Nakamura, Y.; Chan, Samantha; Nakai, T.; Creemers, L. B.; Frauchiger, Daniela Angelika; May, Rahel Deborah; Grad, S.; Tryfonidou, M. A.; Gantenbein, Benjamin (2018). Successful fishing for nucleus pulposus progenitor cells of the intervertebral disc across species. JOR Spine, 1(2), e1018. Wiley 10.1002/jsp2.1018

Frauchiger, Daniela Angelika; Heeb, Silvan Rolf; May, Rahel Deborah; Wöltje, Michael; Benneker, Lorin Michael; Gantenbein, Benjamin (2018). Differentiation of MSC and annulus fibrosus cells on genetically-engineered silk fleece-membrane-composites enriched for GDF-6 or TGF-β3. Journal of orthopaedic research, 36(5), pp. 1324-1333. Wiley 10.1002/jor.23778

May, Rahel Deborah; Frauchiger, Daniela Angelika; Albers, Christoph; Benneker, Lorin Michael; Kohl, Sandro; Gantenbein, Benjamin (2018). Inhibitory Effects of Human Primary Intervertebral Disc Cells on Human Primary Osteoblasts in a Co-Culture System. International journal of molecular sciences, 19(4) Molecular Diversity Preservation International MDPI 10.3390/ijms19041195

Frauchiger, Daniela Angelika; May, Rahel Deborah; Bakirci, Ezgi; Tekari, Adel; Chan, Samantha; W\"oltje, Michael; Benneker, Lorin Michael; Gantenbein, Benjamin (2018). Genipin-Enhanced Fibrin Hydrogel and Novel Silk for Intervertebral Disc Repair in a Loaded Bovine Organ Culture Model. Journal of Functional Biomaterials, 9(3) MDPI 10.3390/jfb9030040

2017

Krismer, Anna; Cabra, Romina Silvia; May, Rahel; Frauchiger, Daniela Angelika; Kohl, Sandro; Ahmad, Sufian; Gantenbein, Benjamin (2017). The biologic response of human anterior cruciate ligamentocytes on collagen-patches to platelet-rich plasma formulations with and without leucocytes. Journal of orthopaedic research, 35(12), pp. 2733-2739. Wiley 10.1002/jor.23599

Wüest, Simon; Plüss, Tobias; Hardegger, Christoph; Felder, Mario; Kunz, Aaron; Fleischli, Benno; Komotar, Carlos; Rüdlinger, Lukas; Albisser, Andreas; Gisler, Thomas; Frauchiger, Daniela Angelika; Egli, Marcel (2017). Electrophysiological Recordings on a Sounding Rocket: Report of a First Attempt Using Xenopus laevis Oocytes. Gravitational and Space Research, 5(2), pp. 43-56.

Frauchiger, Daniela Angelika; Tekari, Adel; Wöltje, Michael; Fortunato, Giuseppino; Benneker, Lorin Michael; Gantenbein, Benjamin (2017). A review of the application of reinforced hydrogels and silk as biomaterials for intervertebral disc repair. European cells & materials eCM, 34, pp. 271-290. University of Wales 10.22203/eCM.v034a17

Tekari, Adel; May, R D; Frauchiger, Daniela Angelika; Chan, S C; Benneker, Lorin Michael; Gantenbein, Benjamin (2017). The BMP2 variant L51P restores the osteogenic differentiation of human mesenchymal stromal cells in the presence of intervertebral disc cells. European cells & materials eCM, 33, pp. 197-210. University of Wales 10.22203/eCM.v033a15

May, Rahel Deborah; Tekari, Adel; Frauchiger, Daniela Angelika; Krismer, A; Benneker, LM; Gantenbein, Benjamin (2017). Efficient Nonviral Transfection of Primary Intervertebral Disc Cells by Electroporation for Tissue Engineering Application. Tissue engineering Part C Methods, 23(1), pp. 30-37. Mary Ann Liebert 10.1089/ten.TEC.2016.0355

Frauchiger, Daniela Angelika; Tekari, Adel; Benneker, Lorin Michael; Sakai, Daisuke; Grad, Sibylle; Stoyanov, Jivko; Bertolo, Alessandro; Gantenbein, Benjamin (2017). Nucleus pulposus progenitor cells isolation and injection into degenerative disc (Unpublished). In: AOSpine Masters Symposium-Novel and Emerging Technologies in Translational Medicine. 23 September 2017.

Frauchiger, Daniela Angelika; Benneker, Lorin Michael; Gantenbein, Benjamin (2017). Comparing two annulus fibrosus injury models in loaded bovine organ culture (Unpublished). In: AOSpine Masters Symposium-Novel and Emerging Technologies in Translational Medicine. Bern. 23 September 2017.

May, Rahel Deborah; Tekari, Adel; Frauchiger, Daniela Angelika; Benneker, Lorin Michael; Kohl, Sandro; Gantenbein, Benjamin (2017). Influence of intervertebral disc cells on matrix mineralization in primary human osteoblasts (Unpublished). In: Conference Proceedings of Biospine 6. Berlin, Germany. 25-29 April.

Frauchiger, Daniela Angelika; Tekari, Adel; Benneker, Lorin Michael; Sakai, Daisuke; Gantenbein, Benjamin (2017). Destiny of allogeneic Tie2+ cells from isolation to injection into intervertebral discs in organ explant culture (Unpublished). In: Global Spine Congress. Milan, Italy. 5 May 2017.

Frauchiger, Daniela Angelika; Heeb, Silvan; Tekari, Adel; Wöltje, Michael; Benneker, Lorin Michael; Gantenbein, Benjamin (2017). Intervertebral disc repair by combining genipin-enhanced fibrin hydrogel and engineered silk-fleece (Unpublished). In: Global Spine Congress. 5 May 2017.

Frauchiger, Daniela Angelika; Tekari, Adel; Benneker, Lorin Michael; Sakai, Daisuke; Grad, Sibylle; Gantenbein, Benjamin (2017). Protocols for isolation of nucleus pulposus progenitor cells from bovine intervertebral disc (Unpublished). In: Proceedings of Biospine6. Berlin. 25-29 April.

Frauchiger, Daniela Angelika; Heeb, Silvan; Wöltje, Michael; Benneker, Lorin Michael; Gantenbein, Benjamin (2017). Engineered Bombyx mori silk scaffolds to differentiate human mesenchymal stem cells towards intervertebral disc-like cells for disc repair (Unpublished). In: Proceedings of Biospine6. Berlin. 25-29 April.

Frauchiger, Daniela Angelika; May, Rahel Deborah; Koch, Andreas K.; Benneker, Lorin Michael; Gantenbein, Benjamin (2017). Real-time monitoring of glucose consumption of intervertebral disc cells in 3D culture. Spine - affiliated society meeting abstracts. Athens, Greece: Lippincott Williams & Wilkins

Frauchiger, Daniela Angelika; Heeb, Silvan; Benneker, Lorin Michael; Wöltje, Michael; Gantenbein, Benjamin (2017). Combined biomaterials approach to repair the intervertebral disc. Spine - affiliated society meeting abstracts, p. 14. Athens, Greece: Lippincott Williams & Wilkins

Frauchiger, Daniela Angelika; Chan, Samantha; Benneker, Lorin Michael; Gantenbein, Benjamin (2017). Comparison of two AF injury models in organ culture (Unpublished). In: Proceedings of TERMIS-EU Chapter Meeting. Davos. June 2017.

Frauchiger, Daniela Angelika; Tekari, Adel; Woeltje, Michael; Benneker, Lorin Michael; Gantenbein, Benjamin (2017). Combining engineered silk composite and genipin-enhanced fibrin hydrogel to repair the annulus fibrosus (Unpublished). In: TERMIS-Eu Chapter Meeting. Davos. June 2017.

Frauchiger, Daniela Angelika; May, Rahel Deborah; Koch, Andreas K.; Benneker, Lorin Michael; Gantenbein, Benjamin (2017). Glucose uptake of human intervertebral disc cells in 3d culture monitored in real-time (Unpublished). In: TERMIS EU Chapter Meeting. Davos. June 2017.

Frauchiger, Daniela Angelika; Tekari, Adel; Benneker, Lorin Michael; Sakai, Daisuke; Grad, Sibylle; Stoyanov, Jivko; Bertolo, Alessandro; Gantenbein, Benjamin (2017). Fishing nucleus pulposus progenitor cells from bovine intervertebral discs using three different sorting methods (Unpublished). In: Proceedings of TERMIS-EU Chapter. Davos. 25 June 2017.

Frauchiger, Daniela Angelika; Heeb, Silvan; Wöltje, Michael; Benneker, Lorin Michael; Gantenbein, Benjamin (2017). Differentiation of human mesenchymal stem cell differentiation towards intervertebral disc-like cells on engineered Bombyx mori silk scaffolds for disc repair. In: Proceedings of TERMIS-EU Meeting. Davos.

Frauchiger, Daniela Angelika; Heeb, Silvan; Tekari, Adel; Wöltje, M.; Benneker, Lorin Michael; Gantenbein, Benjamin (2017). Intervertebral Disc Repair By A Combination Of Genipin-enhanced Fibrin Hydrogel And Growth Factor-enriched Silk-fleece. In: Annual Meeting / Orthopaedic Research Society. San Diego. 19-22 March 2017.

Frauchiger, Daniela Angelika; Tekari, Adel; Benneker, Lorin Michael; Sakai, D.; Gantenbein, Benjamin (2017). The Fate of Allogeneic Injected Angiopoietin-1 Receptor Tie2+ Cells in Intervertebral Disc Organ Culture (Unpublished). In: Proceedings of the Orthopaedic Research Society. San Diego. 19-22 March.

May, Rahel Deborah; Tekari, Adel; Chan, Samantha; Frauchiger, Daniela Angelika; Benneker, Lorin Michael; Gantenbein, Benjamin (2017). The Natural Expression of BMP Antagonists in Intervertebral Disc Cells (Unpublished). In: Proceedings of the Orthopaedic Research Society. San Diego.

May, Rahel Deborah; Tekari, Adel; Frauchiger, Daniela Angelika; Krismer, Anna; Benneker, Lorin Michael; Gantenbein, Benjamin (2017). Optimizing electroporation parameters for non-viral intervertebral disc cells for tissue engineering (Unpublished). In: TERMIS EU Chapter Meeting. Davos.

May, Rahel Deborah; Frauchiger, Daniela Angelika; Tekari, Adel; Benneker, Lorin Michael; Kohl, Sandro; Gantenbein, Benjamin (2017). Formation of calcium deposits in primary human osteoblasts in the presence of intervertebral disc cells (Unpublished). In: TERMIS EU Chapter meeting. Davos. 26 - 30 June.

May, Rahel Deborah; Frauchiger, Daniela Angelika; Tekari, Adel; Kohl, Sandro; Benneker, Lorin Michael; Gantenbein, Benjamin (2017). Effect of exogenous stimulation of the BMP antagonists Gremlin and Noggin on primary human osteoblasts and mesenchymal stem cells (Unpublished). In: TERMIS-EU Chapter Meeting. Davos. 26-30 June.

2016

Schmocker, Andreas; Khoushabi, Azadeh; Frauchiger, Daniela Angelika; Gantenbein, Benjamin; Schizas, Constantin; Moser, Christophe; Bourban, Pierre-Etienne; Pioletti, Dominique P (2016). A photopolymerized composite hydrogel and surgical implanting tool for a nucleus pulposus replacement. Biomaterials, 88, pp. 110-119. Elsevier 10.1016/j.biomaterials.2016.02.015

Frauchiger, Daniela Angelika; Benneker, Lorin Michael; Roth, Eva; Gantenbein, Benjamin (2016). Annulus Fibrosus Repair using Genetically Engineered Silk and Genipin-Enhanced Fibringel. Global Spine Journal, 6(1_suppl), s-0036-1582588-s-0036-1582588. Thieme 10.1055/s-0036-1582588

Tekari, Adel; Chan, Samantha C W; Frauchiger, Daniela Angelika; Benneker, Lorin Michael; Heini, Paul Ferdinand; Gantenbein, Benjamin (2016). The BMP2-variant L51P Enhances the Osteogenic Differentiation of Human Mesenchymal Stromal Cells in the Presence of Intervertebral Disc Cells. Global Spine Journal, 6(1_suppl), s-0036-1582610-s-0036-1582610. Thieme 10.1055/s-0036-1582610

Frauchiger, Daniela Angelika; Heeb, Silvan Rolf; Roth, Eva; Wöltje, WM; Benneker, Lorin Michael; Gantenbein, Benjamin (12 February 2016). Genetically engineered silk and genipin-enhanced fibrin hydrogel for annulus fibrosus repair (Unpublished). In: YSBM.ch Symposium 2016. Zürich. 12.02.2016.

May, Rahel; Frauchiger, Daniela Angelika; Gazdhar, Amiq Ur Rahman; Geiser, Thomas; Benneker, Lorin Michael; Gantenbein, Benjamin (12 February 2016). Non-Viral Gene Therapy to Cells of the bovine Intervertebral Disc (Unpublished). In: YSBM.ch Symposium 2016.

2015

Gantenbein, Benjamin; Chan, Samantha; Frauchiger, Daniela Angelika; Benneker, Lorin Michael; Heini, Paul Ferdinand; Tekari, Adel (4 November 2015). In vitro analysis of osteogenic inhibition in non-union spinal fusion caused by intervertebral disc cells. In: Day of Clinical Research 2015, Department of Clinical Research.

Heeb, Silvan Rolf; Frauchiger, Daniela Angelika; Roth, Eva; Gantenbein, Benjamin (4 November 2015). Investigation of Fibrin-Hydrogel-Silk Scaffolds for Restoration of the Intervertebral Disc. In: Day of Clinical Research 2015. Department of Clinical Research (DCR), Bern. 04.11.2015.

Tekari, Adel; Chan, Samantha; Frauchiger, Daniela Angelika; Benneker, Lorin Michael; Heini, Paul Ferdinand; Gantenbein, Benjamin (29 June 2015). In vitro analysis of osteogenic inhibition in non-union spinal fusion caused by nucleus pulposus cells. In: 11th Swiss Stem Cell Network Annual Meeting. 29.06.2015.

Tekari, Adel; Chan, Samantha; Frauchiger, Daniela Angelika; Wuertz, Karin; Sakai, Daisuke; Benneker, Lorin Michael; Grad, Sibylle; Gantenbein, Benjamin (9 June 2015). Nucleus pulposus contain progenitor-like cells able to differentiate into osteogenic and adipogenic lineages in vitro. European cells & materials eCM, 30(Suppl. 1), p. 66. University of Wales

Tekari, Adel; Chan, Samantha; Frauchiger, Daniela Angelika; Benneker, Lorin Michael; Heini, Paul Ferdinand; Gantenbein, Benjamin (21 May 2015). Investigation of bone inhibition in non-union spinal fusion caused by intervertebral disc cells in vitro (Unpublished). In: Annual Meeting of the SVGO/SBMS (Swiss Bone Mineral Society).

Tekari, Adel; Frauchiger, Daniela Angelika; Benneker, Lorin Michael; Yayon, Avner; Gantenbein, Benjamin (2 May 2015). Evaluation of HA-fibrin-based hydrogel for restoration of degenerated intervertebral disc (Unpublished). In: Engineering Sciences for Biology and Medicine.

Frauchiger, Daniela Angelika; Chan, Samantha CW; Tekari, Adel; Benneker, Lorin Michael; Gantenbein, Benjamin (2015). Repair of Annulus fibrosus with Genipin-enhanced Fibrin Hydrogel and silk membrane- fleece. European spine journal, 24 Berlin: Springer

Frauchiger, Daniela Angelika; Chan, Samantha CW; Roth, Eva; Gantenbein, Benjamin (2015). Intervertebral Disc Repair using Fleece-Membrane Composite Silk Material and Genipin-enhanced Fibrin Hydrogel (Unpublished). In: DKF Research Conference. Bern. 04.11.2015.

Benneker, Lorin Michael; Frauchiger, Daniela Angelika; Gantenbein, Benjamin (2015). Annulus fibrosus Repair with a Genipin-enhanced Fibrin based Hydrogel and silk membrane-fleece (Unpublished). In: 75th Annual Meeting of the Swiss Orthopedic Society SGO.

Frauchiger, Daniela Angelika; Chan, Samantha CW; Benneker, Lorin Michael; Gantenbein, Benjamin (2015). Annulus Fibrosus Repair with the help of a novel Silk membrane-fleece and Genipin-enhanced Fibrin Hydrogel (Unpublished). In: 21th Swiss Conference on Biomaterials and Regenerative Medicine.

May, Rahel; Frauchiger, Daniela Angelika; Gazdhar, Amiq Ur Rahman; Geiser, Thomas; Benneker, Lorin Michael; Gantenbein, Benjamin (2015). NonViral Gene Delivery of Growth and Differentiation Factor 6 (GDF6) to whole bovine Intervertebral Disc. European spine journal, 24, p. 649. Berlin: Springer

Frauchiger, Daniela Angelika; Chan, Samantha CW; Tekari, Adel; Benneker, Lorin Michael; Gantenbein, Benjamin (2015). Repair of Annulus fibrosus with Genipin-enhanced Fibrin Hydrogel and silk membrane- fleece (Unpublished). In: Biospine.org, Proceedings of the 5th International Congress on Biotechnologies for Spinal Surgery.

May, Rahel; Frauchiger, Daniela Angelika; Gazdhar, Amiq Ur Rahman; Geiser, Thomas; Benneker, Lorin Michael; Gantenbein, Benjamin (2015). NonViral Gene Delivery of Growth and Differentiation Factor 6 (GDF6) to whole bovine Intervertebral Disc (Unpublished). In: Biospine.org, Proceedings of the 5th International Congress on Biotechnologies for Spinal Surgery.

2014

Studer, Thomas Paul; Fortunato, Guiseppino; Gadhari, Neha; Frauchiger, Daniela Angelika; Rossi, Ren; Gantenbein, Benjamin (2014). Tailoring silk based nano fibres for human intervertebral disc repair. eCM Journal.

Studer, Thomas; Fortunato, Guiseppino; Gadhari, Neha; Frauchiger, Daniela Angelika; Rossi, René; Gantenbein, Benjamin (2014). Engineering niches for intervertebral disc cells using random and aligned silk nano-fibres. European cells & materials eCM, 28(6), p. 36. Basel: University of Wales

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