Hight, Darren Fletcher

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Fehrlin, Eloy S; Hight, Darren; Kaiser, Heiko A; Luedi, Markus M; Huber, Markus; Zubler, Frédéric; Lersch, Friedrich (2023). A Pilot Investigation Evaluating Relative Changes in Fronto-Occipital Alpha and Beta Spectral Power as Measurement of Anesthesia Hypnotic Depth. (In Press). Anesthesia and analgesia International Anesthesia Research Society 10.1213/ANE.0000000000006398

Guay, Christian S; Hight, Darren; Gupta, Gaurang; Kafashan, MohammadMehdi; Luong, Anhthi H; Avidan, Michael S; Brown, Emery N; Palanca, Ben Julian A (2023). Breathe-squeeze: pharmacodynamics of a stimulus-free behavioural paradigm to track conscious states during sedation☆. (In Press). British journal of anaesthesia Elsevier 10.1016/j.bja.2023.01.021

Hight, Darren; Kreuzer, Matthias; Ugen, Gesar; Schuller, Peter; Stüber, Frank; Sleigh, Jamie; Kaiser, Heiko A (2023). Five commercial 'depth of anaesthesia' monitors provide discordant clinical recommendations in response to identical emergence-like EEG signals. (In Press). British journal of anaesthesia Oxford University Press 10.1016/j.bja.2022.12.026


Mirra, A; Casoni, D; Barge, P; Hight, D; Levionnois, O; Spadavecchia, C (2022). Usability of the SedLine® electroencephalographic monitor of depth of anaesthesia in pigs: a pilot study. Journal of clinical monitoring and computing, 36(6), pp. 1635-1646. Springer 10.1007/s10877-022-00807-3

Hight, Darren; Sleigh, Jamie (2022). Consciousness and the outside world: is there anyone listening? British journal of anaesthesia, 128(6), pp. 895-897. Elsevier 10.1016/j.bja.2022.02.001

Obert, David P; Hight, Darren; Sleigh, Jamie; Kaiser, Heiko A; García, Paul S; Schneider, Gerhard; Kreuzer, Matthias (2022). The First Derivative of the Electroencephalogram Facilitates Tracking of Electroencephalographic Alpha Band Activity During General Anesthesia. Anesthesia and analgesia, 134(5), pp. 1062-1071. International Anesthesia Research Society 10.1213/ANE.0000000000005783

Hight, Darren; Schanderhazi, Cornelia; Huber, Markus; Stüber, Frank; Kaiser, Heiko Andreas (2022). Age, minimum alveolar concentration and choice of depth of sedation monitor: examining the paradox of age when using the Narcotrend monitor: A secondary analysis of an observational study. European journal of anaesthesiology, 39(4), pp. 305-314. Lippincott Williams & Wilkins 10.1097/EJA.0000000000001576


Sleigh, J; Hight, Darren (2021). Is complexity complicated? British journal of anaesthesia, 127(2), pp. 173-174. Oxford University Press 10.1016/j.bja.2021.05.014

Kaiser, H. A.; Knapp, J.; Sleigh, J.; Avidan, M. S.; Stüber, F.; Hight, D. (2021). The quantitative EEG in electroencephalogram-based brain monitoring during general anesthesia. Anaesthesist, 70(6), pp. 531-547. Springer-Medizin-Verlag 10.1007/s00101-021-00960-5

Obert, David P.; Schweizer, Catrin; Zinn, Sebastian; Kratzer, Stephan; Hight, Darren; Sleigh, Jamie; Schneider, Gerhard; García, Paul S.; Kreuzer, Matthias (2021). The influence of age on EEG-based anaesthesia indices. Journal of clinical anesthesia, 73, p. 110325. Elsevier 10.1016/j.jclinane.2021.110325

Lersch, Friedrich; Hight, Darren; Frohlich, Flavio (2021). Entrainment of brain network oscillations in anaesthesia. Comment on Br J Anaesth 2020; 125: 330-335. British journal of anaesthesia, 126(1), e11-e12. Oxford University Press 10.1016/j.bja.2020.08.028

García, Paul S.; Kreuzer, Matthias; Hight, Darren; Sleigh, James W. (2021). Effects of noxious stimulation on the electroencephalogram during general anaesthesia: a narrative review and approach to analgesic titration. British journal of anaesthesia, 126(2), pp. 445-457. Oxford University Press 10.1016/j.bja.2020.10.036


Hight, Darren F.; Kaiser, Heiko A.; Sleigh, Jamie W; Avidan, Michael S (2020). Continuing professional development module : An updated introduction to electroencephalogram-based brain monitoring during intended general anesthesia. Canadian journal of anesthesia / Journal canadien d'anesthesie, 67(12), pp. 1858-1878. Springer-Verlag 10.1007/s12630-020-01820-3

Kaiser, Heiko A.; Hirschi, Trevor; Sleigh, Callum; Reineke, David; Hartwich, Volker; Stucki, Monika; Rummel, Christian; Sleigh, Jamie; Hight, Darren (2020). Comorbidity-dependent changes in alpha and broadband electroencephalogram power during general anaesthesia for cardiac surgery. British journal of anaesthesia, 125(4), pp. 456-465. Elsevier 10.1016/j.bja.2020.06.054

Kreuzer, Matthias; Stern, Matthew A; Hight, Darren; Berger, Sebastian; Schneider, Gerhard; Sleigh, James W; García, Paul S (2020). Spectral and Entropic Features Are Altered by Age in the Electroencephalogram in Patients under Sevoflurane Anesthesia. Anesthesiology, 132(5), pp. 1003-1016. Wolters Kluwer Health 10.1097/ALN.0000000000003182

Lersch, Friedrich; Jerney, Pascal; Kaiser, Heiko; Willy, Cédric; Steck, Katharina; Hight, Darren; Zubler, Frédéric (2020). Actimetry-Documented Persistent Periodic Limb Movements During EEG-Confirmed Deep General Anesthesia. A & A practice, 14(6), e01183. Wolters Kluwer 10.1213/XAA.0000000000001183

Kaiser, Heiko; Hight, Darren; Avidan, Michael S (2020). A narrative review of electroencephalogram-based monitoring during cardiovascular surgery. Current opinion in anaesthesiology, 33(1), pp. 92-100. Wolters Kluwer Health 10.1097/ACO.0000000000000819

Hutt, Axel; Lefebvre, Jérémie; Hight, Darren; Kaiser, Heiko (2020). Phase Coherence Induced by Additive Gaussian and Non-gaussian Noise in Excitable Networks With Application to Burst Suppression-Like Brain Signals. Frontiers in applied mathematics and statistics, 5 Frontiers 10.3389/fams.2019.00069

Kaiser, Heiko A.; Peus, Marie; Luedi, Markus; Lersch, Friedrich; Krejci, Vladimir; Reineke, David; Sleigh, Jamie; Hight, Darren (2020). Frontal electroencephalogram reveals emergence-like brain activity occurring during transition periods in cardiac surgery. British journal of anaesthesia, 125(3), pp. 291-297. Elsevier 10.1016/j.bja.2020.05.064


Kaiser, Heiko; Hirschi, Trevor; Hartwich, Volker; Stucki, Monika; Rummel, Christian; Reineke, David; Hight, Darren (2019). Decreasing Frontal Electroencephalogram Alpha Power and Increasing Sensitivity to Volatile Anesthetics Over 3 Surgeries Within 7 Months: A Case Report. A & A practice, 13(7), pp. 274-277. Wolters Kluwer 10.1213/XAA.0000000000001053

Hight, Darren; Lüdi, Markus; Reineke, David; Eberle, Balthasar; Kaiser, Heiko (May 2019). Mind the gap: using the electroencephalogram (EEG) to uncover potential emergence during cardiac surgery. Anesthesia and analgesia, 128(5), pp. 453-454. International Anesthesia Research Society

Kaiser, Heiko; Hirschi, Trevor; Eberle, Balthasar; Reineke, David; Rummel, Christian; Hight, Darren (May 2019). Age and comorbidity-dependent changes in the electroencephalogram during isoflurane general anesthesia. Anesthesia and analgesia, 128(5), pp. 460-461. International Anesthesia Research Society

Gaskell, Amy; Pullon, Rebecca; Hight, Darren; Termaat, Jonathan; Mans, Gay; Voss, Logan; Kreuzer, Matthias; Schmid, Sebastian; Kratzer, Stephan; Rodriguez, Amy; Schneider, Gerhard; Garcia, Paul; Sleigh, Jamie (2019). Modulation of frontal EEG alpha oscillations during maintenance and emergence phases of general anaesthesia to improve early neurocognitive recovery in older patients: protocol for a randomised controlled trial. Trials, 20(1), p. 146. BioMed Central 10.1186/s13063-019-3178-x

Kaiser, Heiko; Hight, Darren (2019). The meaning and impact of interpreting the EEG when using EEG derived ‘depth of anesthesia’ indices. Trends in Anaesthesia and Critical Care, 25, pp. 12-13. Elsevier 10.1016/j.tacc.2019.01.005

Hight, Darren F; Gaskell, Amy L.; Kreuzer, Matthias; Voss, Logan J.; García, Paul S.; Sleigh, Jamie W. (2019). Transient electroencephalographic alpha power loss during maintenance of general anaesthesia. British journal of anaesthesia, 122(5), pp. 635-642. Elsevier 10.1016/j.bja.2018.11.029

Berger-Estilita, Joana; Steck, Katharina; Vetter, Christian Thomas; Seidel, Kathleen; Krejci, Vladimir; Hight, Darren; Kaiser, Heiko (2019). A case report of several intraoperative convulsions while using the Narcotrend monitor: Significance and predictive use. Medicine, 98(47), e18004. Lippincott Williams & Wilkins 10.1097/MD.0000000000018004


Hight, Darren; Rummel, Christian; Stucki, Monika Pia; Krejci, Vladimir; Lersch, Friedrich; Hartwich, Volker; Kaiser, Heiko (30 April 2018). Decreasing frontal EEG Alpha Power over three surgeries within seven months: accelerated brain aging through progressive frailty? (Unpublished). In: International Anesthesia Research Society annual meeting/Neuroscience in Anesthesiology and Perioperative Medicine. Chicago. April 30, 2018.

Hight, Darren; Stucki, Monika Pia; Krejci, Vladimir; Lersch, Friedrich; Hartwich, Volker; Rummel, Christian; Kaiser, Heiko (29 April 2018). Alpha power decreases with age during isoflurane anesthesia (Unpublished). In: International Anesthesiology Research Society annual meeting/Neuroscience in Anesthesiology and Perioperative Medicine. Chicago. April 29 2018.

Hutt, Axel; Lefebvre, Jérémie; Hight, Darren; Sleigh, Jamie (2018). Suppression of underlying neuronal fluctuations mediates EEG slowing during general anaesthesia. NeuroImage, 179, pp. 414-428. Elsevier 10.1016/j.neuroimage.2018.06.043

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