Keogh-Stroka, Deborah M.

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Jakob, Manuel O.; Sánchez-Taltavull, Daniel; Yilmaz, Bahtiyar; Malinka, Thomas; Mooser, Catherine; Spari, Daniel; Salm, Lilian A.; Freiburghaus, Katrin; Pereyra, David; Hapfelmeier, Siegfried; Masoodi, Mojgan; Starlinger, Patrick; Stroka, Deborah; Tschan, Franziska; Candinas, Daniel; Gomez de Agüero, Mercedes; Beldi, Guido (19 September 2019). Compartmentalization of intestinal bacteria by hepatic ILC3s prevents infections after surgery (bioRxiv). Cold spring Harbor Laboratory 10.1101/773150

Kudira, Ramesh; Malinka, Thomas; Kohler, Andreas; Dosch, Michel; Gomez de Agüero Tamargo, Maria de la Mercedes; Melin, Nicolas; Haegele, S; Starlinger, P; Maharjan, Niran; Saxena, Smita; Keogh, Adrian; Keogh-Stroka, Deborah M.; Candinas, Daniel; Beldi, Guido (2016). P2X1 regulated IL-22 secretion by innate lymphoid cells is required for efficient liver regeneration. Hepatology, 63(6), pp. 2004-2017. Wiley Interscience 10.1002/hep.28492

Kudira, Ramesh; Malinka, Thomas; Kohler, Andreas; Dosch, Michel; Gomez de Agüero Tamargo, Maria de la Mercedes; Melin, Nicolas; Haegele, S; Starlinger, P; Maharjan, Niran; Saxena, Smita; Keogh, Adrian; Keogh-Stroka, Deborah M.; Candinas, Daniel; Beldi, Guido (2016). P2X1 regulated IL-22 secretion by innate lymphoid cells is required for efficient liver regeneration (Unpublished). In: Keystone Symposium. Vancouver. 29.01.2016.

Keogh-Stroka, Deborah M.; Plock, Jan Alexander; Beldi, Guido; Frese, Steffen R.; Keogh, Adrian; Bisch-Knaden, Sonja Maria; Dufour, Jean-François; Brunner, Thomas; Candinas, Daniel (2006). Temporary hypoxic stress protects the liver from Fas-mediated apoptosis and ischemia reperfusion injury. In: 93. Jahreskongress der Schweizerischen Gesellschaft für Chirurgie. Lugano, Switzerland. 21.-23.6.2006.

Yes

Ferro, Iolanda; Gavini, Jacopo; Gallo, Stefano; Bracher, Lisamaria; Landolfo, Marc; Candinas, Daniel; Keogh-Stroka, Deborah M.; Polacek, Norbert (2021). The human vault RNA enhances tumorigenesis and chemoresistance through the lysosome in hepatocellular carcinoma. Autophagy, pp. 1-13. Landes Bioscience 10.1080/15548627.2021.1922983

Baier, Felix Alexander; Sánchez-Taltavull, Daniel; Yarahmadov, Tural; Castellà, Cristina Gómez; Jebbawi, Fadi; Keogh, Adrian; Tombolini, Riccardo; Odriozola, Adolfo; Castro Dias, Mariana; Deutsch, Urban; Furuse, Mikio; Engelhardt, Britta; Zuber, Benoît; Odermatt, Alex; Candinas, Daniel; Keogh-Stroka, Deborah M. (2021). Loss of claudin-3 impairs hepatic metabolism, biliary barrier function and cell proliferation in the murine liver. (In Press). Cellular and molecular gastroenterology and hepatology, 12(2), pp. 745-767. Elsevier 10.1016/j.jcmgh.2021.04.003

Melin, Nicolas; Sánchez-Taltavull, Daniel; Fahrner, René; Keogh, Adrian; Dosch, Michel; Büchi, Isabel; Zimmer, Yitzhak; Medová, Michaela; Beldi, Guido; Aebersold, Daniel M.; Candinas, Daniel; Stroka, Deborah (2021). Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury. Cell death & disease, 12(4), p. 366. Nature Publishing Group 10.1038/s41419-021-03654-3

Dommann, Noëlle; Sánchez Taltavull, Daniel; Eggs, Linda; Birrer, Fabienne Esther; Brodie, Tess; Salm, Lilian; Baier, Felix Alexander; Medova, Michaela; Humbert, Magali; Tschan, Mario; Beldi, Guido; Candinas, Daniel; Stroka, Deborah (2020). The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer. Cancers, 12(7) MDPI AG 10.3390/cancers12071913

Sánchez-Taltavull, Daniel; Perkins, Theodore J; Dommann, Noelle; Melin, Nicolas; Keogh, Adrian; Candinas, Daniel; Stroka, Deborah; Beldi, Guido (2020). Bayesian correlation is a robust gene similarity measure for single-cell RNA-seq data. NAR genomics and bioinformatics, 2(1) Oxford University Press 10.1093/nargab/lqaa002

Gavini, Jacopo; Dommann, Noëlle; Jakob, Manuel O.; Keogh, Adrian; Bouchez, Laure C; Karkampouna, Sofia; Kruithof-de Julio, Marianna; Medova, Michaela; Zimmer, Yitzhak; Schläfli, Anna M; Tschan, Mario P.; Candinas, Daniel; Stroka, Deborah; Banz, Vanessa (2019). Verteporfin-induced lysosomal compartment dysregulation potentiates the effect of sorafenib in hepatocellular carcinoma. Cell death & disease, 10(10), p. 749. Springer Nature 10.1038/s41419-019-1989-z

Castro Dias, Mariana; Coisne, Caroline; Lazarevic, Ivana; Baden, Pascale; Hata, Masaki; Iwamoto, Noriko; Ferreira Francisco, David Miguel; Vanlandewijck, Michael; He, Liqun; Baier, Felix A.; Stroka, Deborah; Bruggmann, Rémy; Lyck, Ruth; Enzmann, Gaby; Deutsch, Urban; Betsholtz, Christer; Furuse, Mikio; Tsukita, Shoichiro; Engelhardt, Britta (2019). Publisher Correction: Claudin-3-deficient C57BL/6J mice display intact brain barriers. Scientific reports, 9(1), p. 10702. Springer Nature 10.1038/s41598-019-43511-0

Melhem, Hassan; Kallol, Sampada; Huang, Xiao; Lüthi, Michael; Ontsouka, Edgar; Keogh, Adrian; Stroka, Deborah; Thormann, Wolfgang; Schneider, Henning; Albrecht, Christiane (2019). Placental secretion of apolipoprotein A1 and E: the anti-atherogenic impact of the placenta. Scientific Reports, 9(1), p. 6225. Nature Publishing Group 10.1038/s41598-019-42522-1

Dosch, Michel; Zindel, Joël; Jebbawi, Fadi; Melin, Nicolas; Sanchez-Taltavull, Daniel; Stroka, Deborah; Candinas, Daniel; Beldi, Guido (2019). Connexin-43-dependent ATP release mediates macrophage activation during sepsis. eLife, 8 10.7554/eLife.42670

Mota Castro Dias, Mariana; Coisne, Caroline Marie; Lazarevic, Ivana; Baden, Pascale; Hata, Masaki; Iwamoto, Noriko; Francisco, David Miguel Ferreira; Vanlandewijck, Michael; He, Liqun; Baier, Felix Alexander; Keogh-Stroka, Deborah M.; Bruggmann, Rémy; Lyck, Ruth; Enzmann, Gaby; Deutsch, Urban; Betsholtz, Christer; Furuse, Mikio; Tsukita, Shoichiro; Engelhardt, Britta (2019). Claudin-3-deficient C57BL/6J mice display intact brain barriers. Scientific Reports, 9(1), p. 203. Nature Publishing Group 10.1038/s41598-018-36731-3

Górecka, Agata Joanna; Salemi, Souzan; Haralampieva, Deana; Moalli, Federica; Keogh-Stroka, Deborah M.; Candinas, Daniel; Eberli, Daniel; Brügger, Lukas (2018). Autologous transplantation of adipose-derived stem cells improves functional recovery of skeletal muscle without direct participation in new myofiber formation. Stem cell research & therapy, 9(1), p. 195. BioMed Central 10.1186/s13287-018-0922-1

Glück, Astrid Andreina; Orlando, Eleonora; Leiser, Dominic; Poliakova, Michaela; Nisa Hernández, Lluís; Quintin, Aurelie; Gavini, Jacopo; Keogh-Stroka, Deborah M.; Berezowska, Sabina; Bubendorf, Lukas; Blaukat, Andree; Aebersold, Daniel; Medova, Michaela; Zimmer, Yitzhak (2018). Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxia. Oncogene, 37(30), pp. 4181-4196. Nature Publishing Group 10.1038/s41388-018-0256-6

Karkampouna, Sofia; van der Helm, Danny; Gray, Peter C; Chen, Lanpeng; Klima, Irena; Grosjean, Joël; Burgmans, Mark C; Farina-Sarasqueta, Arantza; Snaar-Jagalska, Ewa B; Keogh-Stroka, Deborah M.; Terracciano, Luigi; van Hoek, Bart; Schaapherder, Alexander F; Osanto, Susan; Thalmann, George; Verspaget, Hein W; Coenraad, Minneke J; Kruithof-de Julio, Marianna (2018). CRIPTO promotes an aggressive tumour phenotype and resistance to treatment in hepatocellular carcinoma. Journal of pathology, 245(3), pp. 297-310. Wiley 10.1002/path.5083

Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Montani, Matteo; Loforese, Giulio; Sladky, Valentina; He, Zhaoyue; Bachmann, Daniel; Wicki, Simone; Villunger, Andreas; Keogh-Stroka, Deborah M.; Kaufmann, Thomas (2018). BOK promotes chemical-induced hepatocarcinogenesis in mice. Cell death and differentiation, 25(4), pp. 706-718. Nature Publishing Group 10.1038/s41418-017-0008-0

Melin, Nicolas; Fahrner, René; Keogh, Adrian; Medova, Michaela; Zimmer, Yitzhak; Aebersold, Daniel; Candinas, Daniel; Beldi, Guido; Keogh-Stroka, Deborah M. (2018). Direct and indirect hepatoprotective mechanism of CBLB502 a TLR5 agonist. Journal of hepatology, 68, S140-S141. Elsevier 10.1016/S0168-8278(18)30497-5

Kohler, Andreas; Büchi, Isabel; Melin, Nicolas; Bayer, F.; McCoy, Kathleen; Candinas, Daniel; Keogh-Stroka, Deborah M. (2018). The IL-33/ST2 axes contributes to hepatocyte proliferation and promotes development of hepatocellular carcinoma. HPB : official journal of The International Hepato-Pancreato-Biliary Association, 20(Suppl. 2), S261-S261. Elsevier 10.1016/j.hpb.2018.06.205

Melin, Nicolas; Sánchez Taltavull, Daniel; Petit, B.; Herman, E.; Zimmer, Yitzhak; Candinas, Daniel; Vozenin, M.C.; Aebersold, Daniel; Keogh-Stroka, Deborah M. (2018). SP-0330: Science slam: Report back from ESTRO mobility grants biology: Development of a radiation induced liver damage model. Radiotherapy and oncology, 127(Suppl. 1), S175-S176. Elsevier 10.1016/S0167-8140(18)30640-6

Loforese, Giulio; Malinka, Thomas; Keogh, Adrian; Baier, Felix; Simillion, Cedric André Marie; Montani, Matteo; Halazonetis, Thanos D; Candinas, Daniel; Keogh-Stroka, Deborah M. (2017). Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2. EMBO molecular medicine, 9(1), pp. 46-60. EMBO Press 10.15252/emmm.201506089

Francica, Paola; Nisa Hernandez, Lluis; Aebersold, Daniel; Langer, Rupert; Bladt, Friedhelm; Blaukat, Andree; Keogh-Stroka, Deborah M.; Martínez, María Rodríguez; Zimmer, Yitzhak; Medova, Michaela (2016). Depletion of FOXM1 via MET Targeting Underlies Establishment of a DNA Damage-Induced Senescence Program in Gastric Cancer. Clinical cancer research, 22(21), pp. 5322-5336. American Association for Cancer Research 10.1158/1078-0432.CCR-15-2987

Lugli, Natalia; Kamileri, Irene; Keogh, Adrian; Malinka, Thomas; Sarris, Michalis E; Talianidis, Iannis; Schaad, Olivier; Candinas, Daniel; Halazonetis, Thanos D; Keogh-Stroka, Deborah M. (2016). R-spondin 1 and noggin facilitate expansion of resident stem cells from non-damaged gallbladders. EMBO reports, 17(5), pp. 769-779. Nature Publishing Group 10.15252/embr.201642169

Studer, Peter; da Silva, C G; Revuelta Cervantes, J M; Mele, A; Csizmadia, E; Siracuse, J J; Damrauer, S M; Peterson, C R; Candinas, Daniel; Keogh-Stroka, Deborah M.; Ma, A; Bhasin, M; Ferran, C (2015). Significant lethality following liver resection in A20 heterozygous knockout mice uncovers a key role for A20 in liver regeneration. Cell death and differentiation, 22(12), pp. 2068-2077. Nature Publishing Group 10.1038/cdd.2015.52

Leiser, Dominic; Medova, Michaela; Mikami, Kei; Nisa Hernandez, Lluis; Keogh-Stroka, Deborah M.; Blaukat, Andree; Bladt, Friedhelm; Aebersold, Daniel; Zimmer, Yitzhak (2015). KRAS and HRAS mutations confer resistance to MET targeting in preclinical models of MET-expressing tumor cells. Molecular oncology, 9(7), pp. 1434-1446. Elsevier 10.1016/j.molonc.2015.04.001

Keogh-Stroka, Deborah M.; Keogh, Adrian; Vu, Dung; Fort, Alfredo; Stoffel, Michael Hubert; Kühni, Kathrin; Furer, Cynthia; Banz Wüthrich, Vanessa; Demarmels Biasiutti, Franziska; Lämmle, Bernhard; Candinas, Daniel; Neerman-Arbez, Marguerite (2014). In vitro rescue of FGA deletion by lentiviral transduction of an afibrinogenemic patient's hepatocytes. Journal of thrombosis and haemostasis, 12(11), pp. 1874-1879. Wiley-Blackwell 10.1111/jth.12714

Malinka, Thomas; Keogh, Adrian; Kudira, Ramesh; Moghadamrad, Sheida; McCoy, Kathleen; Keogh-Stroka, Deborah M.; Candinas, Daniel; Beldi, Guido (September 2014). Liver regeneration is not impacted in the absence of intestinal microbiota (Unpublished). In: Schweizerische Gesellschaft für Gastroenterologie (SGG) - Schweizerische Gesellschaft für Viszeralchirurgie (SGVC) Annual Congress. Interlaken. 11.-12.9.2014.

Kudira, Ramesh; Malinka, Thomas; Gomez de Agüero Tamargo, Maria de la Mercedes; Keogh, Adrian; Furer, Cynthia; Keogh-Stroka, Deborah M.; Candinas, Daniel; Beldi, Guido (September 2014). Secretion of IL-22 is modulated by CD39 and is required for liver regeneration post partial hepatectomy. In: Schweizerische Gesellschaft für Gastroenterologie (SGG) - Schweizerische Gesellschaft für Viszeralchirurgie (SGVC) Annual Congress. Interlaken. 11.-12.9.2014.

Malinka, Thomas; Keogh, Adrian; Kudira, Ramesh; Moghadamrad, Sheida; McCoy, Kathleen; Keogh-Stroka, Deborah M.; Candinas, Daniel; Beldi, Guido (September 2014). Travel Award: Liver regeneration is not impacted in the absence of intestinal microbiota (Unpublished). In: Schweizerische Gesellschaft für Gastroenterologie (SGG) - Schweizerische Gesellschaft für Viszeralchirurgie (SGVC) Annual Congress. Interlaken. 11.-12.9.2014.

Kudira, Ramesh; Malinka, Thomas; Gomez de Agüero Tamargo, Maria de la Mercedes; Keogh, Adrian; Furer, Cynthia; Keogh-Stroka, Deborah M.; Candinas, Daniel; Beldi, Guido (September 2014). Travel Award: Secretion of IL-22 is modulated by CD39 and is required for liver regeneration post partial hepatectomy (Unpublished). In: Schweizerische Gesellschaft für Gastroenterologie (SGG) - Schweizerische Gesellschaft für Viszeralchirurgie (SGVC) Annual Congress. Interlaken. 11.-12.09.2014.

Fahrner, René; Trochsler, Markus; Corazza, Nadia; Graubardt, Nadine; Keogh, Adrian; Candinas, Daniel; Brunner, Thomas; Keogh-Stroka, Deborah M.; Beldi, Guido (2014). Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand on NK Cells Protects From Hepatic Ischemia-Reperfusion Injury. Transplantation, 97(11), pp. 1102-1109. Lippincott Williams & Wilkins 10.1097/TP.0000000000000101

Balmer, Maria Luisa; Slack, Emma; De Gottardi, Andrea; Lawson, Melissa; Hapfelmeier, Siegfried Hektor; Miele, Luca; Grieco, Antonio; Van Vlierberghe, Hans; Fahrner, René; Patuto, Nicola; Bernsmeier, Christine; Ronchi, Francesca; Wyss, Madeleine; Keogh-Stroka, Deborah M.; Dickgreber, Nina; Heim, Markus H; McCoy, Kathy D; Macpherson, Andrew (2014). The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota. Science translational medicine, 6(237), 237ra66. American Association for the Advancement of Science 10.1126/scitranslmed.3008618

Fahrner, René; Patsenker, Eleanora; De Gottardi, Andrea; Stickel, Felix; Montani, Matteo; Keogh-Stroka, Deborah M.; Candinas, Daniel; Beldi, Guido (2014). Elevated liver regeneration in response to pharmacological reduction of elevated portal venous pressure by terlipressin after partial hepatectomy. Transplantation, 97(9), pp. 892-900. Lippincott Williams & Wilkins 10.1097/TP.0000000000000045

Malinka, Thomas; Keogh, Adrian; Kudira, Ramesh; Moghadamrad, Sheida; McCoy, Kathleen; Keogh-Stroka, Deborah M.; Candinas, Daniel; Beldi, Guido (May 2014). Liver regeneration is not impacted in the absence of intestinal microbiota. (Unpublished). In: Annual meeting of the Swiss Surgical Society. Bern. 21.-23.05.2014.

Kim-Fuchs, Corina; Winterhalder, Sebastian; Winter, Annja; Malinka, Thomas; Born, Diana; Schäfer, Stephan; Keogh-Stroka, Deborah M.; Gloor, Beat; Candinas, Daniel; Angst, Eliane (2014). The Silencing of N-myc Downstream-Regulated Gene-1 in an Orthotopic Pancreatic Cancer Model Leads to More Aggressive Tumor Growth and Metastases. Digestive surgery, 31(2), pp. 135-142. Karger 10.1159/000363065

Edelmann, Simone; Fahrner, René; Malinka, Thomas; Song, Bryan H.; Keogh-Stroka, Deborah M.; Mermod, Nicolas (2014). Nuclear Factor I-C acts as a regulator of hepatocyte proliferation at the onset of liver regeneration. Liver international, 35(4), pp. 1185-1194. Blackwell Munksgaard 10.1111/liv.12697

Medová, Michaela; Pochon, Benoît; Streit, Bruno; Blank-Liss, Wieslawa; Francica, Paola; Stroka, Deborah; Keogh, Adrian; Aebersold, Daniel M.; Blaukat, Andree; Bladt, Friedhelm; Zimmer, Yitzhak (2013). The novel ATP-competitive inhibitor of the MET hepatocyte growth factor receptor EMD1214063 displays inhibitory activity against selected MET-mutated variants. Molecular cancer therapeutics, 12(11), pp. 2415-2424. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-13-0151

Portmann, Simone; Fahrner, René; Lechleiter, Antje; Keogh, Adrian; Overney, Sarah; Lämmle, Alexander; Mikami, Kei; Montani, Matteo; Tschan, Mario; Candinas, Daniel; Keogh-Stroka, Deborah M. (2013). Antitumor effect of SIRT1 inhibition in human HCC tumor models in vitro and in vivo. Molecular cancer therapeutics, 12(4), pp. 499-508. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-12-0700

Kudira, Ramesh; Breu, Karin; Keogh, Adrian; Keogh-Stroka, Deborah M.; Candinas, Daniel; Beldi, Guido (March 2013). Extracellular nucleotides modulate the secretion of IL-22 by hepatic innate lymphoid cells. In: World immune regulation meeting Davos. Davos. 13.-16.3.2013.

Graubardt, Nadine; Fahrner, René; Trochsler, Markus; Keogh, Adrian; Breu, Karin; Furer, Cynthia; Keogh-Stroka, Deborah M.; Robson, Simon C.; Slack, Emma; Candinas, Daniel; Beldi, Guido (2013). Promotion of liver regeneration by natural killer cells in a murine model is dependent on extracellular adenosine triphosphate phosphohydrolysis. Hepatology, 57(5), pp. 1969-1979. Wiley Interscience 10.1002/hep.26008

Laemmle, Alexander; Lechleiter, Antje; Roh, Vincent; Schwarz, Christa; Portmann, Simone; Furer, Cynthia; Keogh, Adrian; Tschan, Mario P; Candinas, Daniel; Vorburger, Stephan A; Stroka, Deborah (2012). Inhibition of SIRT1 Impairs the Accumulation and Transcriptional Activity of HIF-1α Protein under Hypoxic Conditions. PLoS ONE, 7(3), e33433. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0033433

Wagner, Markus; Roh, Vincent; Strehlen, Michael; Laemmle, Alexander; Stroka, Deborah; Egger, Bernhard; Trochsler, Markus; Hunt, Kelly K; Candinas, Daniel; Vorburger, Stephan A (2009). Effective treatment of advanced colorectal cancer by rapamycin and 5-FU/oxaliplatin monitored by TIMP-1. Journal of gastrointestinal surgery, 13(10), pp. 1781-90. New York, N.Y.: Springer-Verlag 10.1007/s11605-009-0948-x

Roh, V; Laemmle, A; Von Holzen, U; Stroka, D; Dufour, Jean-François; Hunt, K K; Candinas, D; Vorburger, S A (2008). Dual induction of PKR with E2F-1 and IFN-alpha to enhance gene therapy against hepatocellular carcinoma. Cancer gene therapy, 15(10), pp. 636-44. New York, N.Y.: Nature Publishing Group 10.1038/cgt.2008.34

Piguet, A; Ledermann, C; Zimmermann, A; Keogh-Stroka, Deborah M.; Dufour, Jean-François (2007). Hypoxia worsens non-alcoholic steatohepatitis. Journal of hepatology, 46(46), S10. Amsterdam: Elsevier 10.1016/S0168-8278(07)61616-X

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