Läppchen, Tilman

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2018

Läppchen, Tilman; Kiefer, Yvonne; Holland, Jason P.; Bartholomä, Mark D. (2018). In vitro and in vivo evaluation of the bifunctional chelator NODIA-Me in combination with a prostate-specific membrane antigen targeting vector. Nuclear medicine and biology, 60, pp. 45-54. Elsevier 10.1016/j.nucmedbio.2018.03.002

Läppchen, Tilman; Holland, Jason P.; Kiefer, Yvonne; Bartholomä, Mark D. (2018). Preparation and preclinical evaluation of a 68Ga-labelled c(RGDfK) conjugate comprising the bifunctional chelator NODIA-Me. EJNMMI Radiopharmacy and Chemistry, 3(1), p. 6. Springer 10.1186/s41181-018-0043-2

Weinmann, Christian; Holland, Jason P.; Läppchen, Tilman; Scherer, Harald; Maus, Stephan; Stemler, Tobias; Bohnenberger, Hendrik; Ezziddin, Samer; Kurz, Philipp; Bartholomä, Mark D. (2018). Optimized synthesis and indium complex formation with the bifunctional chelator NODIA-Me. Organic & biomolecular chemistry, 16(40), pp. 7503-7512. Royal Society of Chemistry 10.1039/c8ob01981a

2017

Läppchen, Tilman; Rossin, Raffaella; van Mourik, Tiemen R; Gruntz, Guillaume; Hoeben, Freek J M; Versteegen, Ron M; Janssen, Henk M; Lub, Johan; Robillard, Marc S (2017). DOTA-tetrazine probes with modified linkers for tumor pretargeting. Nuclear medicine and biology, 55, pp. 19-26. Elsevier 10.1016/j.nucmedbio.2017.09.001

Schmidtke, Alexander; Läppchen, Tilman; Weinmann, Christian; Bier-Schorr, Lorenz; Keller, Manfred; Kiefer, Yvonne; Holland, Jason P; Bartholomä, Mark D (2017). Gallium Complexation, Stability, and Bioconjugation of 1,4,7-Triazacyclononane Derived Chelators with Azaheterocyclic Arms. Inorganic chemistry, 56(15), pp. 9097-9110. American Chemical Society 10.1021/acs.inorgchem.7b01129

van de Steeg, Evita; Läppchen, Tilman; Aguilera, Begoña; Jansen, Harm T; Muilwijk, Daan; Vermue, Rick; van der Hoorn, José W; Donato, Katia; Rossin, Raffaella; de Visser, Peter C; Vlaming, Maria L H (2017). Feasibility of SPECT-CT Imaging to Study the Pharmacokinetics of Antisense Oligonucleotides in a Mouse Model of Duchenne Muscular Dystrophy. Nucleic acid therapeutics, 27(4), pp. 221-231. Mary Ann Liebert 10.1089/nat.2016.0649

Läppchen, Tilman; Tönnesmann, Roswitha; Eersels, Jos; Meyer, Philipp T; Maecke, Helmut R; Rylova, Svetlana N (2017). Radioiodinated Exendin-4 Is Superior to the Radiometal-Labelled Glucagon-Like Peptide-1 Receptor Probes Overcoming Their High Kidney Uptake. PLoS ONE, 12(1), e0170435. Public Library of Science 10.1371/journal.pone.0170435

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