Stocker, Achim

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Baeriswyl, Stéphane; Gan, Bee Ha; Siriwardena, Thissa N.; Visini, Ricardo; Robadey, Maurane; Javor, Sacha; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2019). X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes. ACS Chemical Biology, 14(4), pp. 758-766. American Chemical Society 10.1021/acschembio.9b00047

Baeriswyl, Stéphane; Javor, Sacha; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2019). X‐Ray Crystal Structure of a Second‐Generation Peptide Dendrimer in Complex with Pseudomonas aeruginosa Lectin LecB. Helvetica chimica acta, 102(9) Wiley 10.1002/hlca.201900178


Bermúdez, Luisa; Del Pozo, Talía; Silvestre Lira, Bruno; de Godoy, Fabiana; Boos, Irene; Romanò, Cecilia; Previtali, Viola; Almeida, Juliana; Bréhélin, Claire; Asis, Ramón; Quadrana, Leandro; Demarco, Diego; Alseekh, Saleh; Salinas Gamboa, Rigel; Pérez-Flores, Laura; Dominguez, Pia Guadalupe; Rothan, Christophe; Fernie, Alisdair Robert; González, Maurício; Stocker, Achim; ... (2018). A Tomato Tocopherol-Binding Protein Sheds Light on Intracellular α-Tocopherol Metabolism in Plants. Plant & cell physiology, 59(11), pp. 2188-2203. Oxford Academic 10.1093/pcp/pcy191


Achim Stocker (2017). Nanospheres of sec14-like proteins and cognate ligands (PCT/EP2017/051,409)

Aeschimann, Walter; Staats, Stefanie; Kammer, Stephan Martin; Olieric, Natacha; Jeckelmann, Jean-Marc; Fotiadis, Dimitrios José; Netscher, Thomas; Rimbach, Gerald; Cascella, Michele; Stocker, Achim (2017). Self-assembled α-Tocopherol Transfer Protein Nanoparticles Promote Vitamin E Delivery Across an Endothelial Barrier. Scientific Reports, 7(1) Nature Publishing Group 10.1038/s41598-017-05148-9

Aeschimann, Walter; Staats, Stefanie; Kammer, Stephan Martin; Olieric, Natacha; Jeckelmann, Jean-Marc; Fotiadis, Dimitrios José; Netscher, Thomas; Rimbach, Gerald; Cascella, Michele; Stocker, Achim (2017). Self-assembled α-Tocopherol Transfer Protein Nanoparticles Promote Vitamin E Delivery Across an Endothelial Barrier (Unpublished). In: 52nd Bürgenstock Conference. Brunnen, Switzerland. 30th of April to 4th of May.

Di Bonaventura, Ivan; Jin, Xian; Visini, Ricardo; Probst, Daniel; Javor, Sacha; Gan, Bee-Ha; Michaud, Gaëlle; Natalello, Antonino; Doglia, Silvia Maria; Köhler, Thilo; van Delden, Christian; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2017). Chemical space guided discovery of antimicrobial bridged bicyclic peptides against Pseudomonas aeruginosa and its biofilms. Chemical Science, 8(10), pp. 6784-6798. The Royal Society of Chemistry 10.1039/C7SC01314K

He, Runze; Di Bonaventura, Ivan; Visini, Ricardo; Gan, Bee-Ha; Fu, Yongchun; Probst, Daniel; Lüscher, Alexandre; Köhler, Thilo; van Delden, Christian; Stocker, Achim; Hong, Wenjing; Darbre, Tamis; Reymond, Jean-Louis (2017). Design, crystal structure and atomic force microscopy study of thioether ligated d , l -cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa. Chemical Science, 8(11), pp. 7464-7475. The Royal Society of Chemistry 10.1039/C7SC01599B


Stocker, Achim (7 November 2016). Homeostasis of α-Tocopherol and of 11-cis-Retinal is Regulated by Proteins of the Sec14 Superfamily (Unpublished). In: Seminar. Institute of Human Nutrition and Food Science, Christian-Albrechts-University, Kiel, Germany. 07.11.2016.

Probst, Markus; Aeschimann, Walter; Chau, Thi T H; Langenegger, Simon Matthias; Stocker, Achim; Häner, Robert (2016). Structural insight into DNA-assembled oligochromophores: crystallographic analysis of pyrene- and phenanthrene-modified DNA in complex with BpuJI endonuclease. Nucleic acids research, 44(15), pp. 7079-7089. Information Retrieval Ltd. 10.1093/nar/gkw644

Röthlisberger, Pascal; Istrate, Alena; Marcaida Lopez, M. J.; Visini, Ricardo; Stocker, Achim; Reymond, Jean-Louis; Leumann, Christian (2016). X-ray structure of a lectin-bound DNA duplex containing an unnatural phenanthrenyl pair. Chemical communications, 52(26), pp. 4749-4752. Royal Society of Chemistry 10.1039/c6cc00374e

Michaud, Gaëlle; Visini, Ricardo; Bergman, Manfred Max; Salerno, Gianluca; Bosco, Rosa; Gillon, Emilie; Richichi, Barbara; Nativi, Cristina; Imberty, Anne; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2016). Overcoming antibiotic resistance in Pseudomonas aeruginosa biofilms using glycopeptide dendrimers. Chemical Science, 7(1), pp. 166-182. The Royal Society of Chemistry 10.1039/c5sc03635f


Bergman, Manfred Max; Michaud, Gaëlle; Visini, Ricardo; Jin, Xian; Gillon, Emilie; Stocker, Achim; Imberty, Anne; Darbre, Tamis; Reymond, Jean-Louis (2015). Multivalency effects in Pseudomonas aeruginosa biofilm inhibition and dispersal by glycopeptide dendrimers targeting lectin LecA. Organic & biomolecular chemistry, 14(1), pp. 138-148. Royal Society of Chemistry 10.1039/C5OB01682G

Wagner, Anika; Piegholdt, Stefanie; Rabe, Doerte; Baenas, Nieves; Schloesser, Anke; Eggersdorfer, Manfred; Stocker, Achim; Rimbach, Gerald (2015). Epigallocatechin gallate (EGCG) affects glucose metabolism and enhances fitness and life span in Drosophila melanogaster. OncoTarget, 6(31), pp. 30568-30578. Impact Journals LLC 10.18632/oncotarget.5215

Visini, Ricardo; Bergman, Manfred Max; Michaud, Gaelle; Pertici, Francesca; Fu, Ou; Pukin, Aliaksei; Branson, Thomas; Thies-Weesie, Dominique; Kemmink, Johan; Gillon, Emilie; Imberty, Anne; Stocker, Achim; Darbre, Tamis; Pieters, Roland; Reymond, Jean-Louis (2015). Structural Insight into Multivalent Galactoside Binding to Pseudomonas aeroginosa lectin LecA. ACS Chemical Biology, 10(11), pp. 2455-2462. American Chemical Society 10.1021/acschembio.5b00302

Lamprakis, Christos; Stocker, Achim; Cascella, Michele (2015). Mechanisms of recognition and binding of α-TTP to the plasma membrane by multi-scale molecular dynamics simulations. Frontiers in Molecular Biosciences, 2(36) Frontiers 10.3389/fmolb.2015.00036

Christen, Monika; Marcaida, Maria; Lamprakis, Christos; Aeschimann, Walter; Vaithilingam, Jathana; Schneider, Petra; Hilbert, Manuel; Schneider, Gisbert; Cascella, Michele; Stocker, Achim (2015). Evidence for direct squalene and 2,3-oxidosqualene binding by supernatant protein factor. Journal of structural biology, 190(190), pp. 261-270. Elsevier 10.1016/j.jsb.2015.05.001


Piegholdt, Stefanie; Pallauf, Kathrin; Esatbeyoglu, Tuba; Speck, Nancy; Reiss, Karina; Ruddigkeit, Lars; Stocker, Achim; Huebbe, Patricia; Rimbach, Gerald (2014). Biochanin A and prunetin improve epithelial barrier function in intestinal CaCo-2 cells via downregulation of ERK, NF-κB, and tyrosine phosphorylation. Free radical biology & medicine, 70, pp. 255-264. Elsevier 10.1016/j.freeradbiomed.2014.02.025

Bartoloni, Marco; Waltersperger, Sandro; Bumann, Mario; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2014). Stereoselective synthesis and structure determination of a bicyclo[3.3.2]decapeptide. Arkivoc, 2014(3), p. 113. Michigan Publishing 10.3998/ark.5550190.p008.500

Bolze, Christin Saskia; Helbling, Rachel; Owen, Robin L.; Pearson, Arwen R.; Pompidor, Guillaume; Dworkowski, Florian; Furrer, Julien; Golczak, Marcin; Fuchs, Martin; Palczewski, Krzysztof; Cascella, Michele; Stocker, Achim (2014). Human Cellular Retinaldehyde-Binding Protein Has Secondary Thermal 9- cis -Retinal Isomerase Activity. Journal of the American Chemical Society, 136(1), pp. 137-146. American Chemical Society 10.1021/ja411366w

Helbling, Rachel E.; Lamprakis, Christos; Aeschimann, Walter; Bolze, Cristin S.; Stocker, Achim; Cascella, Michele (2014). Mechanisms of Ligand–Protein Interaction in Sec-14-like Transporters Investigated by Computer Simulations. CHIMIA, 68(9), pp. 615-619. Bern: Schweizerische Chemische Gesellschaft 10.2533/chimia.2014.615


Kadam, Rameshwar U.; Bergman, Manfred Max; Garg, Divita; Gabrieli, Gabriele; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2013). Structure-Based Optimization of the Terminal Tripeptide in Glycopeptide Dendrimer Inhibitors of Pseudomonas aeruginosa Biofilms Targeting LecA. Chemistry - a European journal, 19(50), pp. 17054-17063. Wiley-VCH 10.1002/chem.201302587

Helbling, Rachel E.; Bolze, Christin Saskia; Golczak, Marcin; Palczewski, Krzysztof; Stocker, Achim; Cascella, Michele (2013). Cellular Retinaldehyde Binding Protein—Different Binding Modes and Micro-Solvation Patterns for High-Affinity 9- cis - and 11- cis -Retinal Substrates. Journal of physical chemistry - B, 117(37), pp. 10719-10729. American Chemical Society 10.1021/jp405410t

Kadam, Rameshwar U.; Garg, Divita; Schwartz, Julian; Visini, Ricardo; Sattler, Michael; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2013). CH−π “T-Shape” Interaction with Histidine Explains Binding of Aromatic Galactosides to Pseudomonas aeruginosa Lectin LecA. ACS Chemical Biology, 8(9), pp. 1925-1930. American Chemical Society 10.1021/cb400303w

Cascella, Michele; Bärfuss, Simon; Stocker, Achim (2013). Cis-retinoids and the chemistry of vision. Archives of biochemistry and biophysics, 539(2), pp. 187-195. Elsevier 10.1016/


Helbling, Rachel E.; Aeschimann, Walter; Simona, Fabio; Stocker, Achim; Cascella, Michele (2012). Engineering Tocopherol Selectivity in alpha-TTP: A Combined In Vitro/In Silico Study. PLoS ONE, 7(11), e49195. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0049195

He, Xiaoqin; Lobsiger, Joel; Stocker, Achim (2012). Molecular Clues to Bothnia-Type Retinal Dystrophy. In: LaVail, Matthew M.; Ash, John D.; Anderson, Robert E.; Hollyfield, Joe G.; Grimm, Christian (eds.) Retinal Degenerative Diseases. Advances in Experimental Medicine and Biology: Vol. 723 (pp. 589-594). Heidelberg: Springer Verlag 10.1007/978-1-4614-0631-0_75

Stocker, Achim (2012). Combined X-ray crystallographic, in situ UV-Vis and QM/MM studies highlight alternate retinal binding modes in CRALBP, Presentation given at the 15th International Conference on Retinal Proteins, 30.9.2012 in Ascona, Switzerland.


Kadam, Rameshwar U.; Bergman, Manfred Max; Hurley, Matthew; Garg, Divita; Cacciarini, Martina; Swiderska, Magdalena A.; Nativi, Cristina; Sattler, Michael; Smyth, Alan R.; Williams, Paul; Camara, Miguel; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2011). A Glycopeptide Dendrimer Inhibitor of the Galactose-Specific Lectin LecA and of Pseudomonas aeruginosa Biofilms. Angewandte Chemie (International ed.), 50(45), pp. 10631-10635. Weinheim: Wiley-VCH 10.1002/anie.201104342

Ernst, I. M.; Wagner, A. E.; Schuemann, C.; Storm, N.; Hoppner, W.; Doring, F.; Stocker, A.; Rimbach, G. (2011). Allyl-, butyl- and phenylethyl-isothiocyanate activate Nrf2 in cultured fibroblasts. Pharmacological research, 63(3), pp. 233-240. Oxford: Elsevier 10.1016/j.phrs.2010.11.005


He, Xiaoqin; Lobsiger, Joel; Stocker, Achim (2009). Bothnia dystrophy is caused by domino-like rearrangements in cellular retinaldehyde-binding protein mutant R234W. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 106(44), pp. 18545-18550. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.0907454106


Stocker, Achim; Keis, Stefanie; Vonck, Janet; Cook, Gregory; Dimroth, Peter (2007). The Structural Basis for Unidirectional Rotation of Thermoalkaliphilic F1-ATPase. Structure, 15(8), pp. 904-914. Cambridge, Mass.: Cell Press 10.1016/j.str.2007.06.009


Keis, Stefanie; Stocker, Achim; Dimroth, Peter; Cook, Gregory (2006). Inhibition of ATP hydrolysis by thermoalkaliphilic F1Fo-ATP synthase is controlled by the C terminus of the epsilon subunit. Journal of bacteriology, 188(11), pp. 3796-3804. Washington, D.C.: American Society for Microbiology 10.1128/JB.00040-06

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