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Arena, Chiara; Gado, Francesca; Di Cesare Mannelli, Lorenzo; Cervetto, Chiara; Carpi, Sara; Reynoso-Moreno, Ines; Polini, Beatrice; Vallini, Erika; Chicca, Stefano; Lucarini, Elena; Bertini, Simone; D'Andrea, Felicia; Digiacomo, Maria; Poli, Giulio; Tuccinardi, Tiziano; Macchia, Marco; Gertsch, Jürg; Marcoli, Manuela; Nieri, Paola; Ghelardini, Carla; ... (2020). The endocannabinoid system dual-target ligand N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-fluorobenzyl)-6-methyl-2-oxo-pyridine-3-carboxamide improves disease severity in a mouse model of multiple sclerosis. European journal of medicinal chemistry, 208, p. 112858. Elsevier 10.1016/j.ejmech.2020.112858
Gado, Francesca; Arena, Chiara; Fauci, Cristiana La; Reynoso-Moreno, Ines; Bertini, Simone; Digiacomo, Maria; Meini, Serena; Poli, Giulio; Macchia, Marco; Tuccinardi, Tiziano; Gertsch, Jürg; Chicca, Andrea; Manera, Clementina (2020). Modification on the 1,2-dihydro-2-oxo-pyridine-3-carboxamide core to obtain multi-target modulators of endocannabinoid system. Bioorganic chemistry, 94, p. 103353. Elsevier 10.1016/j.bioorg.2019.103353
Chicca, Andrea; Arena, Chiara; Bertini, Simone; Gado, Francesca; Ciaglia, Elena; Abate, Mario; Digiacomo, Maria; Lapillo, Margherita; Poli, Giulio; Bifulco, Maurizio; Macchia, Marco; Tuccinardi, Tiziano; Gertsch, Jürg; Manera, Clementina (2018). Polypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid system. European journal of medicinal chemistry, 154, pp. 155-171. Elsevier 10.1016/j.ejmech.2018.05.019
Bertini, Simone; Chicca, Andrea; Gado, Francesca; Arena, Chiara; Nieri, Daniela; Digiacomo, Maria; Saccomanni, Giuseppe; Zhao, Pingwei; Abood, Mary E; Macchia, Marco; Gertsch, Jürg; Manera, Clementina (2017). Novel analogs of PSNCBAM-1 as allosteric modulators of cannabinoid CB1 receptor. Bioorganic & medicinal chemistry, 25(24), pp. 6427-6434. Elsevier 10.1016/j.bmc.2017.10.015
Bertini, Simone; Chicca, Andrea; Arena, Chiara; Chicca, Stefano; Saccomanni, Giuseppe; Gertsch, Jürg; Manera, Clementina; Macchia, Marco (2016). Synthesis and pharmacological evaluation of new biphenylic derivatives as CB2 receptor ligands. European journal of medicinal chemistry, 116, pp. 252-266. Elsevier Masson SAS 10.1016/j.ejmech.2016.03.072
