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Gogola, Ewa; Duarte, Alexandra A; de Ruiter, Julian R; Wiegant, Wouter W; Schmid, Jonas A; de Bruijn, Roebi; James, Dominic I; Guerrero Llobet, Sergi; Vis, Daniel J; Annunziato, Stefano; van den Broek, Bram; Barazas, Marco; Kersbergen, Ariena; van de Ven, Marieke; Tarsounas, Madalena; Ogilvie, Donald J; van Vugt, Marcel; Wessels, Lodewyk F A; Bartkova, Jirina; Gromova, Irina; ... (2018). Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality. Cancer cell, 33(6), 1078-1093.e12. Cell Press 10.1016/j.ccell.2018.05.008
Duarte, Alexandra A; Gogola, Ewa; Sachs, Norman; Barazas, Marco; Annunziato, Stefano; R de Ruiter, Julian; Velds, Arno; Blatter, Sohvi Tuulikki; Houthuijzen, Julia M; van de Ven, Marieke; Clevers, Hans; Borst, Piet; Jonkers, Jos; Rottenberg, Sven (2018). BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance. Nature methods, 15(2), pp. 134-140. Nature Publishing Group 10.1038/nmeth.4535
Pajic, Marina; Blatter, Sohvi Tuulikki; Guyader, Charlotte; Gonggrijp, Maaike; Kersbergen, Ariena; Küçükosmanoğlu, Aslι; Sol, Wendy; Drost, Rinske; Jonkers, Jos; Borst, Piet; Rottenberg, Sven (2017). Selected Alkylating Agents Can Overcome Drug Tolerance of G-like Tumor Cells and Eradicate BRCA1-Deficient Mammary Tumors in Mice. Clinical cancer research, 23(22), pp. 7020-7033. American Association for Cancer Research 10.1158/1078-0432.CCR-17-1279
Tkáč, Ján; Xu, Guotai; Adhikary, Hemanta; Young, Jordan T F; Gallo, David; Escribano-Díaz, Cristina; Krietsch, Jana; Orthwein, Alexandre; Munro, Meagan; Sol, Wendy; Al-Hakim, Abdallah; Lin, Zhen-Yuan; Jonkers, Jos; Borst, Piet; Brown, Grant W; Gingras, Anne-Claude; Rottenberg, Sven; Masson, Jean-Yves; Durocher, Daniel (2016). HELB Is a Feedback Inhibitor of DNA End Resection. Molecular cell, 61(3), pp. 405-418. Cell Press 10.1016/j.molcel.2015.12.013
Planells-Cases, Rosa; Lutter, Darius; Guyader, Charlotte; Gerhards, Nora Merete; Ullrich, Florian; Elger, Deborah A; Kucukosmanoglu, Asli; Xu, Guotai; Voss, Felizia K; Reincke, S Momsen; Stauber, Tobias; Blomen, Vincent A; Vis, Daniel J; Wessels, Lodewyk F; Brummelkamp, Thijn R; Borst, Piet; Rottenberg, Sven; Jentsch, Thomas J (2015). Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs. The EMBO Journal, 34(24), pp. 2993-3008. EMBO Press 10.15252/embj.201592409
Xu, Guotai; Chapman, J Ross; Brandsma, Inger; Yuan, Jingsong; Mistrik, Martin; Bouwman, Peter; Bartkova, Jirina; Gogola, Ewa; Warmerdam, Daniël; Barazas, Marco; Jaspers, Janneke E; Watanabe, Kenji; Pieterse, Mark; Kersbergen, Ariena; Sol, Wendy; Celie, Patrick H N; Schouten, Philip C; van den Broek, Bram; Salman, Ahmed; Nieuwland, Marja; ... (2015). REV7 counteracts DNA double-strand break resection and affects PARP inhibition. Nature, 521(7553), pp. 541-544. Macmillan Journals Ltd. 10.1038/nature14328
Jaspers, Janneke E; Sol, Wendy; Kersbergen, Ariena; Schlicker, Andreas; Guyader, Charlotte; Xu, Guotai; Wessels, Lodewyk; Borst, Piet; Jonkers, Jos; Rottenberg, Sven (2015). BRCA2-Deficient Sarcomatoid Mammary Tumors Exhibit Multidrug Resistance. Cancer research, 75(4), pp. 732-741. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-14-0839
