 | Up a level |
Franica, Paola; Mutlu, Merve; Blomen, Vincent A.; Oliveira, Catarina; Nowicka, Zuzanna; Trenner, Anika; Gerhards, Nora M.; Bouwman, Peter; Stickel, Elmer; Hekkelman, Maarten L.; Lingg, Lea; Klebic, Ismar; van den Ven, Marieke; de Korte-Grimmerink, Renske; Howald, Denise; Jonkers, Jos; Sartori, Alessandro A.; Fendler, Wojciech; Chapman, J. Ross; Brummelkamp, Thijn; ... (2020). Functional radiogenetic profiling implicates ERCC6L2 in non-homologous end joining. Cell reports, 32(8), p. 108068. Cell Press 10.1016/j.celrep.2020.108068
Pantelidou, Constantia; Sonzogni, Olmo; de Oliveira Taveira, Mateus; Mehta, Anita K; Kothari, Aditi; Wang, Dan; Visal, Tanvi; Li, Michelle K; Pinto, Jocelin; Castrillon, Jessica A; Cheney, Emily M; Bouwman, Peter; Jonkers, Jos; Rottenberg, Sven; Guerriero, Jennifer L; Wulf, Gerburg M; Shapiro, Geoffrey I (2019). PARP inhibitor efficacy depends on CD8+ T cell recruitment via intratumoral STING pathway activation in BRCA-deficient models of triple-negative breast cancer. Cancer discovery, 9(6), pp. 722-737. American Association for Cancer Research 10.1158/2159-8290.CD-18-1218
Barazas, Marco; Gasparini, Alessia; Huang, Yike; Küçükosmanoğlu, Asli; Annunziato, Stefano; Bouwman, Peter; Sol, Wendy; Kersbergen, Ariena; Proost, Natalie; de Korte-Grimmerink, Renske; van de Ven, Marieke; Jonkers, Jos; Borst, Gerben R; Rottenberg, Sven (2019). Radiosensitivity Is an Acquired Vulnerability of PARPi-Resistant BRCA1-Deficient Tumors. Cancer research, 79(3), pp. 452-460. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-18-2077
Schoonen, Pepijn M; Talens, Francien; Stok, Colin; Gogola, Ewa; Heijink, Anne Margriet; Bouwman, Peter; Foijer, Floris; Tarsounas, Madalena; Blatter, Sohvi Tuulikki; Jonkers, Jos; Rottenberg, Sven; van Vugt, Marcel A T M (2017). Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells. Nature communications, 8(15981), p. 15981. Nature Publishing Group 10.1038/ncomms15981
Drost, Rinske; Dhillon, Kiranjit K; van der Gulden, Hanneke; van der Heijden, Ingrid; Brandsma, Inger; Cruz, Cristina; Chondronasiou, Dafni; Castroviejo-Bermejo, Marta; Boon, Ute; Schut, Eva; van der Burg, Eline; Wientjens, Ellen; Pieterse, Mark; Klijn, Christiaan; Klarenbeek, Sjoerd; Loayza-Puch, Fabricio; Elkon, Ran; van Deemter, Liesbeth; Rottenberg, Sven; van de Ven, Marieke; ... (2016). BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1. Journal of clinical investigation, 126(8), pp. 2903-2918. American Society for Clinical Investigation 10.1172/JCI70196
Xu, Guotai; Chapman, J Ross; Brandsma, Inger; Yuan, Jingsong; Mistrik, Martin; Bouwman, Peter; Bartkova, Jirina; Gogola, Ewa; Warmerdam, Daniël; Barazas, Marco; Jaspers, Janneke E; Watanabe, Kenji; Pieterse, Mark; Kersbergen, Ariena; Sol, Wendy; Celie, Patrick H N; Schouten, Philip C; van den Broek, Bram; Salman, Ahmed; Nieuwland, Marja; ... (2015). REV7 counteracts DNA double-strand break resection and affects PARP inhibition. Nature, 521(7553), pp. 541-544. Macmillan Journals Ltd. 10.1038/nature14328
