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Yasinska, Valentyna; Gómez, Cristina; Kolmert, Johan; Ericsson, Magnus; Pohanka, Anton; James, Anna; Andersson, Lars I; Sparreman-Mikus, Maria; Sousa, Ana R; Riley, John H; Bates, Stewart; Bakke, Per S; Zounemat Kermani, Nazanin; Caruso, Massimo; Chanez, Pascal; Fowler, Stephen J; Geiser, Thomas; Howarth, Peter H; Horváth, Ildikó; Krug, Norbert; ... (2023). Low levels of endogenous anabolic androgenic steroids in females with severe asthma taking corticosteroids. ERJ Open Research, 9(5) European Respiratory Society 10.1183/23120541.00269-2023
Brandsma, Joost; Schofield, James P R; Yang, Xian; Strazzeri, Fabio; Barber, Clair; Goss, Victoria M; Koster, Grielof; Bakke, Per S; Caruso, Massimo; Chanez, Pascal; Dahlén, Sven-Erik; Fowler, Stephen J; Horváth, Ildikó; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Sandström, Thomas; Shaw, Dominick E; Chung, Kian Fan; Singer, Florian; ... (2023). Stratification of asthma by lipidomic profiling of induced sputum supernatant. Journal of allergy and clinical immunology, 152(1), pp. 117-125. Elsevier 10.1016/j.jaci.2023.02.032
Reinke, Stacey N; Naz, Shama; Chaleckis, Romanas; Gallart-Ayala, Hector; Kolmert, Johan; Kermani, Nazanin Z; Tiotiu, Angelica; Broadhurst, David I; Lundqvist, Anders; Olsson, Henric; Ström, Marika; Wheelock, Åsa M; Gómez, Cristina; Ericsson, Magnus; Sousa, Ana R; Riley, John H; Bates, Stewart; Scholfield, James; Loza, Matthew; Baribaud, Frédéric; ... (2022). Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study. European respiratory journal, 59(6) European Respiratory Society 10.1183/13993003.01733-2021
Hoda, Uruj; Pavlidis, Stelios; Bansal, Aruna T; Takahashi, Kentaro; Hu, Sile; Ng Kee Kwong, Francois; Rossios, Christos; Sun, Kai; Bhavsar, Pankaj; Loza, Matthew; Baribaud, Frederic; Chanez, Pascal; Fowler, Stephen J; Horvath, Ildiko; Montuschi, Paolo; Singer, Florian; Musial, Jacek; Dahlen, Barbro; Krug, Norbert; Sandstrom, Thomas; ... (2022). Clinical and transcriptomic features of persistent exacerbation-prone severe asthma in U-BIOPRED cohort. Clinical and translational medicine, 12(4), e816. 10.1002/ctm2.816
Sparreman Mikus, Maria; Kolmert, Johan; Andersson, Lars I; Östling, Jörgen; Knowles, Richard G; Gómez, Cristina; Ericsson, Magnus; Thörngren, John-Olof; Emami Khoonsari, Payam; Dahlén, Barbro; Kupczyk, Maciej; De Meulder, Bertrand; Auffray, Charles; Bakke, Per S; Beghe, Bianca; Bel, Elisabeth H; Caruso, Massimo; Chanez, Pascal; Chawes, Bo; Fowler, Stephen J; ... (2022). Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation. The European respiratory journal, 59(2) European Respiratory Society 10.1183/13993003.00142-2021
Badi, Yusef Eamon; Pavel, Ana B; Pavlidis, Stelios; Riley, John H; Bates, Stewart; Kermani, Nazanin Zounemat; Knowles, Richard; Kolmert, Johan; Wheelock, Craig E; Worsley, Sally; Uddin, Mohib; Alving, Kjell; Bakke, Per S; Behndig, Annelie; Caruso, Massimo; Chanez, Pascal; Fleming, Louise J; Fowler, Stephen J; Frey, Urs; Howarth, Peter; ... (2022). Mapping atopic dermatitis and anti-IL-22 response signatures to Type 2-low severe neutrophilic asthma. Journal of allergy and clinical immunology, 149(1), pp. 89-101. Elsevier 10.1016/j.jaci.2021.04.010
Alahmadi, Fahad H; Simpson, Andrew J; Gomez, Cristina; Ericsson, Magnus; Thörngren, John-Olof; Wheelock, Craig; Shaw, Dominic E; Fleming, Louise J; Roberts, Graham; Riley, John; Bates, Stewart; Sousa, Ana R; Knowles, Richard; Bansal, Aruna T; Corfield, Julie; Pandis, Ioannis; Sun, Kai; Bakke, Per S; Caruso, Massimo; Chanez, Pascal; ... (2021). Medication Adherence in Patients With Severe Asthma Prescribed Oral Corticosteroids in the U-BIOPRED Cohort. Chest, 160(1), pp. 53-64. Elsevier 10.1016/j.chest.2021.02.023
Kolmert, Johan; Gómez, Cristina; Balgoma, David; Sjödin, Marcus; Bood, Johan; Konradsen, Jon R; Ericsson, Magnus; Thörngren, John-Olof; James, Anna; Mikus, Maria; Sousa, Ana R; Riley, John H; Bates, Stewart; Bakke, Per S; Pandis, Ioannis; Caruso, Massimo; Chanez, Pascal; Fowler, Stephen J; Geiser, Thomas; Howarth, Peter; ... (2021). Urinary Leukotriene E4 and Prostaglandin D2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type-2 Inflammation. American journal of respiratory and critical care medicine, 203(1), pp. 37-53. American Lung Association 10.1164/rccm.201909-1869OC
Bruno, Andreina; Di Sano, Caterina; Simon, Hans-Uwe; Chanez, Pascal; Patti, Angelo Maria; Di Vincenzo, Serena; Dino, Paola; D'Esposito, Vittoria; Formisano, Pietro; Beguinot, Francesco; Pace, Elisabetta (2021). Leptin and TGF-β1 Downregulate PREP1 Expression in Human Adipose-Derived Mesenchymal Stem Cells and Mature Adipocytes. Frontiers in cell and developmental biology, 9, p. 700481. Frontiers 10.3389/fcell.2021.700481
Holguin, Fernando; Cardet, Juan Carlos; Chung, Kian Fan; Diver, Sarah; Ferreira, Diogenes S; Fitzpatrick, Anne; Gaga, Mina; Kellermeyer, Liz; Khurana, Sandhya; Knight, Shandra; McDonald, Vanessa M; Morgan, Rebecca L; Ortega, Victor E; Rigau, David; Subbarao, Padmaja; Tonia, Thomy; Adcock, Ian M; Bleecker, Eugene R; Brightling, Chris; Boulet, Louis-Philippe; ... (2020). Management of Severe Asthma: a European Respiratory Society/American Thoracic Society Guideline. European respiratory journal, 55(1), p. 1900588. European Respiratory Society 10.1183/13993003.00588-2019
Brinkman, Paul; Wagener, Ariane H; Hekking, Pieter-Paul; Bansal, Aruna T; Maitland-van der Zee, Anke-Hilse; Wang, Yuanyue; Weda, Hans; Knobel, Hugo H; Vink, Teunis J; Rattray, Nicholas J; D'Amico, Arnaldo; Pennazza, Giorgio; Santonico, Marco; Lefaudeux, Diane; De Meulder, Bertrand; Auffray, Charles; Bakke, Per S; Caruso, Massimo; Chanez, Pascal; Chung, Kian F; ... (2019). Identification and prospective stability of electronic nose (eNose)-derived inflammatory phenotypes in patients with severe asthma. The Journal of allergy and clinical immunology, 143(5), 1811-1820.e7. Elsevier 10.1016/j.jaci.2018.10.058
Jevnikar, Zala; Östling, Jörgen; Ax, Elisabeth; Calvén, Jenny; Thörn, Kristofer; Israelsson, Elisabeth; Öberg, Lisa; Singhania, Akul; Lau, Laurie C K; Wilson, Susan J; Ward, Jonathan A; Chauhan, Anoop; Sousa, Ana R; De Meulder, Bertrand; Loza, Matthew J; Baribaud, Frédéric; Sterk, Peter J; Chung, Kian Fan; Sun, Kai; Guo, Yike; ... (2019). Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation. Journal of allergy and clinical immunology, 143(2), pp. 577-590. Elsevier 10.1016/j.jaci.2018.05.026
Takahashi, Kentaro; Pavlidis, Stelios; Ng Kee Kwong, Francois; Hoda, Uruj; Rossios, Christos; Sun, Kai; Loza, Matthew; Baribaud, Fred; Chanez, Pascal; Fowler, Steve J; Horvath, Ildiko; Montuschi, Paolo; Singer, Florian; Musial, Jacek; Dahlen, Barbro; Dahlen, Sven-Eric; Krug, Norbert; Sandstrom, Thomas; Shaw, Dominic E; Lutter, Rene; ... (2018). Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis. European respiratory journal, 51(5) European Respiratory Society 10.1183/13993003.02173-2017
Emma, Rosalia; Bansal, Aruna T; Kolmert, Johan; Wheelock, Craig E; Dahlen, Swen-Erik; Loza, Matthew J; De Meulder, Bertrand; Lefaudeux, Diane; Auffray, Charles; Dahlen, Barbro; Bakke, Per S; Chanez, Pascal; Fowler, Stephen J; Horvath, Ildiko; Montuschi, Paolo; Krug, Norbert; Sanak, Marek; Sandstrom, Thomas; Shaw, Dominick E; Fleming, Louise J; ... (2018). Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort. PLoS ONE, 13(9), e0203874. Public Library of Science 10.1371/journal.pone.0203874
Lefaudeux, Diane; De Meulder, Bertrand; Loza, Matthew J; Peffer, Nancy; Rowe, Anthony; Baribaud, Frédéric; Bansal, Aruna T; Lutter, Rene; Sousa, Ana R; Corfield, Julie; Pandis, Ioannis; Bakke, Per S; Caruso, Massimo; Chanez, Pascal; Dahlén, Sven-Erik; Fleming, Louise J; Fowler, Stephen J; Horvath, Ildiko; Krug, Norbert; Montuschi, Paolo; ... (2017). U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics. The Journal of allergy and clinical immunology, 139(6), pp. 1797-1807. Elsevier 10.1016/j.jaci.2016.08.048
Shaw, Dominick E; Sousa, Ana R; Fowler, Stephen J; Fleming, Louise J; Roberts, Graham; Corfield, Julie; Pandis, Ioannis; Bansal, Aruna T; Bel, Elisabeth H; Auffray, Charles; Compton, Chris H; Bisgaard, Hans; Bucchioni, Enrica; Caruso, Massimo; Chanez, Pascal; Dahlén, Barbro; Dahlen, Sven-Erik; Dyson, Kerry; Frey, Urs Peter; Geiser, Thomas; ... (2015). Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort. European respiratory journal, 46(5), pp. 1308-1321. European Respiratory Society 10.1183/13993003.00779-2015
Thamrin, Cindy; Nydegger, Regula; Stern, Georgette; Chanez, Pascal; Wenzel, Sally E; Watt, Rosemary A; FitzPatrick, Susan; Taylor, D Robin; Frey, Urs (2011). Associations between fluctuations in lung function and asthma control in two populations with differing asthma severity. Thorax, 66(12), pp. 1036-42. London: BMJ Publishing Group 10.1136/thx.2010.156489
Thamrin, Cindy; Zindel, Joel; Nydegger, Regula; Reddel, Helen K; Chanez, Pascal; Wenzel, Sally E; FitzPatrick, Susan; Watt, Rosemary A; Suki, Béla; Frey, Urs (2011). Predicting future risk of asthma exacerbations using individual conditional probabilities. Journal of allergy and clinical immunology, 127(6), 1494-502.e3. St. Louis, Mo.: Mosby 10.1016/j.jaci.2011.01.018