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Srivatsa, Sumana; Montazeri, Hesam; Bianco, Gaia; Coto-Llerena, Mairene; Marinucci, Mattia; Ng, Charlotte K Y; Piscuoglio, Salvatore; Beerenwinkel, Niko (2022). Discovery of synthetic lethal interactions from large-scale pan-cancer perturbation screens. Nature communications, 13(1), p. 7748. Nature Publishing Group 10.1038/s41467-022-35378-z
Bianco, Gaia; Coto-Llerena, Mairene; Gallon, John; Kancherla, Venkatesh; Taha-Mehlitz, Stephanie; Marinucci, Mattia; Konantz, Martina; Srivatsa, Sumana; Montazeri, Hesam; Panebianco, Federica; Tirunagaru, Vijaya G; De Menna, Marta; Paradiso, Viola; Ercan, Caner; Dahmani, Ahmed; Montaudon, Elodie; Beerenwinkel, Niko; Kruithof-de Julio, Marianna; Terracciano, Luigi M; Lengerke, Claudia; ... (2022). Author Correction: GATA3 and MDM2 are synthetic lethal in estrogen receptor-positive breast cancers. Communications biology, 5(1), p. 658. Springer Nature 10.1038/s42003-022-03612-5
Zanotti, Sofia; Boot, Gina F; Coto-Llerena, Mairene; Gallon, John; Hess, Gabriel F; Soysal, Savas D; Kollmar, Otto; Ng, Charlotte K Y; Piscuoglio, Salvatore (2022). The Role of Chronic Liver Diseases in the Emergence and Recurrence of Hepatocellular Carcinoma: An Omics Perspective. Frontiers in medicine, 9, p. 888850. Frontiers 10.3389/fmed.2022.888850
Ng, Charlotte K Y; Dazert, Eva; Boldanova, Tuyana; Coto-Llerena, Mairene; Nuciforo, Sandro; Ercan, Caner; Suslov, Aleksei; Meier, Marie-Anne; Bock, Thomas; Schmidt, Alexander; Ketterer, Sylvia; Wang, Xueya; Wieland, Stefan; Matter, Matthias S; Colombi, Marco; Piscuoglio, Salvatore; Terracciano, Luigi M; Hall, Michael N; Heim, Markus H (2022). Integrative proteogenomic characterization of hepatocellular carcinoma across etiologies and stages. Nature Communications, 13(1), p. 2436. Springer Nature 10.1038/s41467-022-29960-8
Bianco, Gaia; Coto-Llerena, Mairene; Gallon, John; Kancherla, Venkatesh; Taha-Mehlitz, Stephanie; Marinucci, Mattia; Konantz, Martina; Srivatsa, Sumana; Montazeri, Hesam; Panebianco, Federica; Tirunagaru, Vijaya G; De Menna, Marta; Paradiso, Viola; Ercan, Caner; Dahmani, Ahmed; Montaudon, Elodie; Beerenwinkel, Niko; Kruithof-de Julio, Marianna; Terracciano, Luigi M; Lengerke, Claudia; ... (2022). GATA3 and MDM2 are synthetic lethal in estrogen receptor-positive breast cancers. Communications biology, 5(1), p. 373. Springer Nature 10.1038/s42003-022-03296-x
Coto-Llerena, Mairene; Benjak, Andrej; Gallon, John; Meier, Marie-Anne; Boldanova, Tuyana; Terracciano, Luigi M; Ng, Charlotte K Y; Piscuoglio, Salvatore (2022). Circulating Cell-Free DNA Captures the Intratumor Heterogeneity in Multinodular Hepatocellular Carcinoma. JCO precision oncology, 6, e2100335. American Society of Clinical Oncology 10.1200/PO.21.00335
Gallon, John; Coto-Llerena, Mairene; Ercan, Caner; Bianco, Gaia; Paradiso, Viola; Nuciforo, Sandro; Taha-Melitz, Stephanie; Meier, Marie-Anne; Boldanova, Tujana; Pérez-Del-Pulgar, Sofía; Rodríguez-Tajes, Sergio; von Flüe, Markus; Soysal, Savas D; Kollmar, Otto; Llovet, Josep M; Villanueva, Augusto; Terracciano, Luigi M; Heim, Markus H; Ng, Charlotte K. Y. and Piscuoglio, Salvatore (2022). Epigenetic priming in chronic liver disease impacts the transcriptional and genetic landscapes of hepatocellular carcinoma. Molecular oncology, 16(3), pp. 665-682. Wiley 10.1002/1878-0261.13154
Marinucci, Mattia; Ercan, Caner; Taha-Mehlitz, Stephanie; Fourie, Lana; Panebianco, Federica; Bianco, Gaia; Gallon, John; Staubli, Sebastian; Soysal, Savas D; Zettl, Andreas; Rauthe, Stephan; Vosbeck, Jürg; Droeser, Raoul A; Bolli, Martin; Peterli, Ralph; von Flüe, Markus; Ng, Charlotte K Y; Kollmar, Otto; Coto-Llerena, Mairene and Piscuoglio, Salvatore (2022). Standardizing Patient-Derived Organoid Generation Workflow to Avoid Microbial Contamination From Colorectal Cancer Tissues. Frontiers in oncology, 11, p. 781833. Frontiers Research Foundation 10.3389/fonc.2021.781833
Ercan, Caner; Coto-Llerena, Mairene; Gallon, John; Fourie, Lana; Marinucci, Mattia; Hess, Gabriel F; Vosbeck, Jürg; Taha-Mehlitz, Stephanie; Boldanova, Tuyana; Meier, Marie-Anne; Tzankov, Alexandar; Matter, Matthias S; Hoffmann, Martin H K; Di Tommaso, Luca; von Flüe, Markus; Ng, Charlotte K. Y.; Heim, Markus H; Soysal, Savas D; Terracciano, Luigi M; Kollmar, Otto; ... (2022). Genomic analysis of focal nodular hyperplasia with associated hepatocellular carcinoma unveils its malignant potential: a case report. Communications medicine, 2, p. 11. Springer Nature 10.1038/s43856-022-00074-y
Montazeri, Hesam; Coto-Llerena, Mairene; Bianco, Gaia; Zangene, Ehsan; Taha-Mehlitz, Stephanie; Paradiso, Viola; Srivatsa, Sumana; de Weck, Antoine; Roma, Guglielmo; Lanzafame, Manuela; Bolli, Martin; Beerenwinkel, Niko; von Flüe, Markus; Terracciano, Luigi M; Piscuoglio, Salvatore; Ng, Charlotte K Y (2021). Systematic identification of novel cancer genes through analysis of deep shRNA perturbation screens. Nucleic acids research, 49(15), pp. 8488-8504. Oxford University Press 10.1093/nar/gkab627
Chen, Qian; Coto-Llerena, Mairene; Suslov, Aleksei; Teixeira, Raphael Dias; Fofana, Isabel; Nuciforo, Sandro; Hofmann, Maike; Thimme, Robert; Hensel, Nina; Lohmann, Volker; Ng, Charlotte K Y; Rosenberger, George; Wieland, Stefan; Heim, Markus H (2021). Interferon lambda 4 impairs hepatitis C viral antigen presentation and attenuates T cell responses. Nature Communications, 12(1), p. 4882. Springer Nature 10.1038/s41467-021-25218-x
Coto-Llerena, Mairene; Tosti, Nadia; Taha-Mehlitz, Stephanie; Kancherla, Venkatesh; Paradiso, Viola; Gallon, John; Bianco, Gaia; Garofoli, Andrea; Ghosh, Souvik; Tang, Fengyuan; Ercan, Caner; Christofori, Gerhard M; Matter, Matthias S; Droeser, Raoul A; Zavolan, Mihaela; Soysal, Savas D; von Flüe, Markus; Kollmar, Otto; Terracciano, Luigi M; Ng, Charlotte K. Y.; ... (2021). Transcriptional Enhancer Factor Domain Family member 4 Exerts an Oncogenic Role in Hepatocellular Carcinoma by Hippo-Independent Regulation of Heat Shock Protein 70 Family Members. Hepatology communications, 5(4), pp. 661-674. Wiley 10.1002/hep4.1656
Taha-Mehlitz, Stephanie; Bianco, Gaia; Coto-Llerena, Mairene; Kancherla, Venkatesh; Bantug, Glenn R; Gallon, John; Ercan, Caner; Panebianco, Federica; Eppenberger-Castori, Serenella; von Strauss, Marco; Staubli, Sebastian; Bolli, Martin; Peterli, Ralph; Matter, Matthias S; Terracciano, Luigi M; von Flüe, Markus; Ng, Charlotte K. Y.; Soysal, Savas D; Kollmar, Otto and Piscuoglio, Salvatore (2021). Adenylosuccinate lyase is oncogenic in colorectal cancer by causing mitochondrial dysfunction and independent activation of NRF2 and mTOR-MYC-axis. Theranostics, 11(9), pp. 4011-4029. Ivyspring International 10.7150/thno.50051
Tosti, Nadia; Cremonesi, Eleonora; Governa, Valeria; Basso, Camilla; Kancherla, Venkatesh; Coto-Llerena, Mairene; Amicarella, Francesca; Weixler, Benjamin; Däster, Silvio; Sconocchia, Giuseppe; Majno, Pietro Edoardo; Christoforidis, Dimitri; Tornillo, Luigi; Terracciano, Luigi; Ng, Charlotte K. Y.; Piscuoglio, Salvatore; von Flüe, Markus; Spagnoli, Giulio; Eppenberger-Castori, Serenella; Iezzi, Giandomenica; ... (2020). Infiltration by IL22-Producing T Cells Promotes Neutrophil Recruitment and Predicts Favorable Clinical Outcome in Human Colorectal Cancer. Cancer immunology research, 8(11), pp. 1452-1462. American Association for Cancer Research 10.1158/2326-6066.CIR-19-0934
Lehmann, Frank Michael; von Burg, Nicole; Ivanek, Robert; Teufel, Claudia; Horvath, Edit; Peter, Annick; Turchinovich, Gleb; Staehli, Daniel; Eichlisberger, Tobias; Gomez de Agüero, Mercedes; Coto-Llerena, Mairene; Prchal-Murphy, Michaela; Sexl, Veronika; Bentires-Alj, Mohamed; Mueller, Christoph; Finke, Daniela (2020). Microbiota-induced tissue signals regulate ILC3-mediated antigen presentation. Nature communications, 11(1), p. 1794. Nature Publishing Group 10.1038/s41467-020-15612-2
Coto-Llerena, Mairene; Ercan, Caner; Kancherla, Venkatesh; Taha-Mehlitz, Stephanie; Eppenberger-Castori, Serenella; Soysal, Savas D; Ng, Charlotte K. Y.; Bolli, Martin; von Flüe, Markus; Nicolas, Guillaume P; Terracciano, Luigi M; Fani, Melpomeni; Piscuoglio, Salvatore (2020). High Expression of FAP in Colorectal Cancer Is Associated With Angiogenesis and Immunoregulation Processes. Frontiers in oncology, 10(979), p. 979. Frontiers Research Foundation 10.3389/fonc.2020.00979
Blumer, Tanja; Fofana, Isabel; Matter, Matthias S; Wang, Xueya; Montazeri, Hesam; Calabrese, Diego; Coto-Llerena, Mairene; Boldanova, Tujana; Nuciforo, Sandro; Kancherla, Venkatesh; Tornillo, Luigi; Piscuoglio, Salvatore; Wieland, Stefan; Terracciano, Luigi M; Ng, Kiu Yan Charlotte; Heim, Markus H (2019). Hepatocellular Carcinoma Xenografts Established From Needle Biopsies Preserve the Characteristics of the Originating Tumors. Hepatology communications, 3(7), pp. 971-986. Wiley 10.1002/hep4.1365