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Yasinska, Valentyna; Gómez, Cristina; Kolmert, Johan; Ericsson, Magnus; Pohanka, Anton; James, Anna; Andersson, Lars I; Sparreman-Mikus, Maria; Sousa, Ana R; Riley, John H; Bates, Stewart; Bakke, Per S; Zounemat Kermani, Nazanin; Caruso, Massimo; Chanez, Pascal; Fowler, Stephen J; Geiser, Thomas; Howarth, Peter H; Horváth, Ildikó; Krug, Norbert; ... (2023). Low levels of endogenous anabolic androgenic steroids in females with severe asthma taking corticosteroids. ERJ Open Research, 9(5) European Respiratory Society 10.1183/23120541.00269-2023
Abdel-Aziz, Mahmoud I; Thorsen, Jonathan; Hashimoto, Simone; Vijverberg, Susanne J H; Neerincx, Anne H; Brinkman, Paul; van Aalderen, Wim; Stokholm, Jakob; Rasmussen, Morten Arendt; Roggenbuck-Wedemeyer, Michael; Vissing, Nadja H; Mortensen, Martin Steen; Brejnrod, Asker Daniel; Fleming, Louise J; Murray, Clare S; Fowler, Stephen J; Frey, Urs; Bush, Andrew; Singer, Florian; Hedlin, Gunilla; ... (2023). Oropharyngeal Microbiota Clusters in Children with Asthma/Wheeze Associate with Allergy, Blood Transcriptomic Immune Pathways and Exacerbations Risk. American journal of respiratory and critical care medicine, 208(2), pp. 142-154. American Thoracic Society 10.1164/rccm.202211-2107OC
Thorsen, Jonathan; Stokholm, Jakob; Rasmussen, Morten Arendt; Roggenbuck-Wedemeyer, Michael; Vissing, Nadja H; Mortensen, Martin S; Brejnrod, Asker D; Fleming, Louise; Bush, Andrew; Roberts, Graham; Singer, Florian; Frey, Urs; Hedlin, Gunilla; Nordlund, Björn; Murray, Clare S; Abdel-Aziz, Mahmoud I; Hashimoto, Simone; van Aalderen, Wim; Maitland-van der Zee, Anke H; Shaw, Dominick; ... (2022). Asthma and Wheeze Severity and the Oropharyngeal Microbiota in Children and Adolescents. Annals of the American Thoracic Society, 19(12), pp. 2031-2043. American Thoracic Society 10.1513/AnnalsATS.202110-1152OC
Reinke, Stacey N; Naz, Shama; Chaleckis, Romanas; Gallart-Ayala, Hector; Kolmert, Johan; Kermani, Nazanin Z; Tiotiu, Angelica; Broadhurst, David I; Lundqvist, Anders; Olsson, Henric; Ström, Marika; Wheelock, Åsa M; Gómez, Cristina; Ericsson, Magnus; Sousa, Ana R; Riley, John H; Bates, Stewart; Scholfield, James; Loza, Matthew; Baribaud, Frédéric; ... (2022). Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study. European respiratory journal, 59(6) European Respiratory Society 10.1183/13993003.01733-2021
Hoda, Uruj; Pavlidis, Stelios; Bansal, Aruna T; Takahashi, Kentaro; Hu, Sile; Ng Kee Kwong, Francois; Rossios, Christos; Sun, Kai; Bhavsar, Pankaj; Loza, Matthew; Baribaud, Frederic; Chanez, Pascal; Fowler, Stephen J; Horvath, Ildiko; Montuschi, Paolo; Singer, Florian; Musial, Jacek; Dahlen, Barbro; Krug, Norbert; Sandstrom, Thomas; ... (2022). Clinical and transcriptomic features of persistent exacerbation-prone severe asthma in U-BIOPRED cohort. Clinical and translational medicine, 12(4), e816. 10.1002/ctm2.816
Eger, Katrien; Paroczai, Dora; Bacon, Alison; Schleich, Florence; Sergejeva, Svetlana; Bourdin, Arnaud; Vachier, Isabelle; Zervas, Eleftherios; Katsoulis, Konstantinos; Papapetrou, Dimosthenis; Kostikas, Konstantinos; Csoma, Zsuzsanna; Heffler, Enrico; Canonica, Giorgio Walter; Grisle, Ineta; Bieksiene, Kristina; Palacionyte, Jolita; Ten Brinke, Anneke; Hashimoto, Simone; Smeenk, Frank W J M; ... (2022). The effect of the COVID-19 pandemic on severe asthma care in Europe: will care change for good? ERJ Open Research, 8(2) European Respiratory Society 10.1183/23120541.00065-2022
Sparreman Mikus, Maria; Kolmert, Johan; Andersson, Lars I; Östling, Jörgen; Knowles, Richard G; Gómez, Cristina; Ericsson, Magnus; Thörngren, John-Olof; Emami Khoonsari, Payam; Dahlén, Barbro; Kupczyk, Maciej; De Meulder, Bertrand; Auffray, Charles; Bakke, Per S; Beghe, Bianca; Bel, Elisabeth H; Caruso, Massimo; Chanez, Pascal; Chawes, Bo; Fowler, Stephen J; ... (2022). Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation. The European respiratory journal, 59(2) European Respiratory Society 10.1183/13993003.00142-2021
Badi, Yusef Eamon; Pavel, Ana B; Pavlidis, Stelios; Riley, John H; Bates, Stewart; Kermani, Nazanin Zounemat; Knowles, Richard; Kolmert, Johan; Wheelock, Craig E; Worsley, Sally; Uddin, Mohib; Alving, Kjell; Bakke, Per S; Behndig, Annelie; Caruso, Massimo; Chanez, Pascal; Fleming, Louise J; Fowler, Stephen J; Frey, Urs; Howarth, Peter; ... (2022). Mapping atopic dermatitis and anti-IL-22 response signatures to Type 2-low severe neutrophilic asthma. Journal of allergy and clinical immunology, 149(1), pp. 89-101. Elsevier 10.1016/j.jaci.2021.04.010
Alahmadi, Fahad H; Simpson, Andrew J; Gomez, Cristina; Ericsson, Magnus; Thörngren, John-Olof; Wheelock, Craig; Shaw, Dominic E; Fleming, Louise J; Roberts, Graham; Riley, John; Bates, Stewart; Sousa, Ana R; Knowles, Richard; Bansal, Aruna T; Corfield, Julie; Pandis, Ioannis; Sun, Kai; Bakke, Per S; Caruso, Massimo; Chanez, Pascal; ... (2021). Medication Adherence in Patients With Severe Asthma Prescribed Oral Corticosteroids in the U-BIOPRED Cohort. Chest, 160(1), pp. 53-64. Elsevier 10.1016/j.chest.2021.02.023
Kolmert, Johan; Gómez, Cristina; Balgoma, David; Sjödin, Marcus; Bood, Johan; Konradsen, Jon R; Ericsson, Magnus; Thörngren, John-Olof; James, Anna; Mikus, Maria; Sousa, Ana R; Riley, John H; Bates, Stewart; Bakke, Per S; Pandis, Ioannis; Caruso, Massimo; Chanez, Pascal; Fowler, Stephen J; Geiser, Thomas; Howarth, Peter; ... (2021). Urinary Leukotriene E4 and Prostaglandin D2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type-2 Inflammation. American journal of respiratory and critical care medicine, 203(1), pp. 37-53. American Lung Association 10.1164/rccm.201909-1869OC
Abdel-Aziz, Mahmoud I; Brinkman, Paul; Vijverberg, Susanne J H; Neerincx, Anne H; de Vries, Rianne; Dagelet, Yennece W F; Riley, John H; Hashimoto, Simone; Chung, Kian Fan; Djukanovic, Ratko; Fleming, Louise J; Murray, Clare S; Frey, Urs; Bush, Andrew; Singer, Florian; Hedlin, Gunilla; Roberts, Graham; Dahlén, Sven-Erik; Adcock, Ian M; Fowler, Stephen J; ... (2020). eNose breath prints as a surrogate biomarker for classifying patients with asthma by atopy. Journal of allergy and clinical immunology, 146(5), pp. 1045-1055. Elsevier 10.1016/j.jaci.2020.05.038
Roberts, Graham; Fontanella, Sara; Selby, Anna; Howard, Rebecca; Filippi, Sarah; Hedlin, Gunilla; Nordlund, Bjorn; Howarth, Peter; Hashimoto, Simone; Brinkman, Peter; Fleming, Louise J; Murray, Clare; Bush, Andrew; Frey, Urs; Singer, Florian; Schoos, Ann-Marie Malby; van Aalderen, Wim; Djukanovic, Ratko; Chung, K Fan; Sterk, Peter J; ... (2020). Connectivity patterns between multiple allergen specific IgE antibodies and their association with severe asthma. Journal of allergy and clinical immunology, 146(4), pp. 821-830. Elsevier 10.1016/j.jaci.2020.02.031
Holguin, Fernando; Cardet, Juan Carlos; Chung, Kian Fan; Diver, Sarah; Ferreira, Diogenes S; Fitzpatrick, Anne; Gaga, Mina; Kellermeyer, Liz; Khurana, Sandhya; Knight, Shandra; McDonald, Vanessa M; Morgan, Rebecca L; Ortega, Victor E; Rigau, David; Subbarao, Padmaja; Tonia, Thomy; Adcock, Ian M; Bleecker, Eugene R; Brightling, Chris; Boulet, Louis-Philippe; ... (2020). Management of Severe Asthma: a European Respiratory Society/American Thoracic Society Guideline. European respiratory journal, 55(1), p. 1900588. European Respiratory Society 10.1183/13993003.00588-2019
Brinkman, Paul; Wagener, Ariane H; Hekking, Pieter-Paul; Bansal, Aruna T; Maitland-van der Zee, Anke-Hilse; Wang, Yuanyue; Weda, Hans; Knobel, Hugo H; Vink, Teunis J; Rattray, Nicholas J; D'Amico, Arnaldo; Pennazza, Giorgio; Santonico, Marco; Lefaudeux, Diane; De Meulder, Bertrand; Auffray, Charles; Bakke, Per S; Caruso, Massimo; Chanez, Pascal; Chung, Kian F; ... (2019). Identification and prospective stability of electronic nose (eNose)-derived inflammatory phenotypes in patients with severe asthma. The Journal of allergy and clinical immunology, 143(5), 1811-1820.e7. Elsevier 10.1016/j.jaci.2018.10.058
Simpson, Andrew J; Hekking, Pieter-Paul; Shaw, Dominick E; Fleming, Louise J; Roberts, Graham; Riley, John H; Bates, Stewart; Sousa, Ana R; Bansal, Aruna T; Pandis, Ioannis; Sun, Kai; Bakke, Per S; Caruso, Massimo; Dahlén, Barbro; Dahlén, Sven-Erik; Horvath, Ildiko; Krug, Norbert; Montuschi, Paolo; Sandstrom, Thomas; Singer, Florian; ... (2019). Treatable traits in the European U-BIOPRED adult asthma cohorts. Allergy, 74(2), pp. 406-411. Wiley 10.1111/all.13629
Jevnikar, Zala; Östling, Jörgen; Ax, Elisabeth; Calvén, Jenny; Thörn, Kristofer; Israelsson, Elisabeth; Öberg, Lisa; Singhania, Akul; Lau, Laurie C K; Wilson, Susan J; Ward, Jonathan A; Chauhan, Anoop; Sousa, Ana R; De Meulder, Bertrand; Loza, Matthew J; Baribaud, Frédéric; Sterk, Peter J; Chung, Kian Fan; Sun, Kai; Guo, Yike; ... (2019). Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation. Journal of allergy and clinical immunology, 143(2), pp. 577-590. Elsevier 10.1016/j.jaci.2018.05.026
Takahashi, Kentaro; Pavlidis, Stelios; Ng Kee Kwong, Francois; Hoda, Uruj; Rossios, Christos; Sun, Kai; Loza, Matthew; Baribaud, Fred; Chanez, Pascal; Fowler, Steve J; Horvath, Ildiko; Montuschi, Paolo; Singer, Florian; Musial, Jacek; Dahlen, Barbro; Dahlen, Sven-Eric; Krug, Norbert; Sandstrom, Thomas; Shaw, Dominic E; Lutter, Rene; ... (2018). Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis. European respiratory journal, 51(5) European Respiratory Society 10.1183/13993003.02173-2017
Hekking, Pieter-Paul; Loza, Matt J; Pavlidis, Stelios; de Meulder, Bertrand; Lefaudeux, Diane; Baribaud, Fred; Auffray, Charles; Wagener, Ariane H; Brinkman, Paul; Lutter, Rene; Bansal, Aruna T; Sousa, Ana R; Bates, Steve A; Pandis, Yannis; Fleming, Louise J; Shaw, Dominique E; Fowler, Stephen J; Guo, Y; Meiser, Andrea; Sun, Kai; ... (2018). Pathway discovery using transcriptomic profiles in adult-onset severe asthma. The Journal of allergy and clinical immunology, 141(4), pp. 1280-1290. Elsevier 10.1016/j.jaci.2017.06.037
Emma, Rosalia; Bansal, Aruna T; Kolmert, Johan; Wheelock, Craig E; Dahlen, Swen-Erik; Loza, Matthew J; De Meulder, Bertrand; Lefaudeux, Diane; Auffray, Charles; Dahlen, Barbro; Bakke, Per S; Chanez, Pascal; Fowler, Stephen J; Horvath, Ildiko; Montuschi, Paolo; Krug, Norbert; Sanak, Marek; Sandstrom, Thomas; Shaw, Dominick E; Fleming, Louise J; ... (2018). Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort. PLoS ONE, 13(9), e0203874. Public Library of Science 10.1371/journal.pone.0203874
Lefaudeux, Diane; De Meulder, Bertrand; Loza, Matthew J; Peffer, Nancy; Rowe, Anthony; Baribaud, Frédéric; Bansal, Aruna T; Lutter, Rene; Sousa, Ana R; Corfield, Julie; Pandis, Ioannis; Bakke, Per S; Caruso, Massimo; Chanez, Pascal; Dahlén, Sven-Erik; Fleming, Louise J; Fowler, Stephen J; Horvath, Ildiko; Krug, Norbert; Montuschi, Paolo; ... (2017). U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics. The Journal of allergy and clinical immunology, 139(6), pp. 1797-1807. Elsevier 10.1016/j.jaci.2016.08.048
Loza, Matthew J; Djukanovic, Ratko; Chung, Kian Fan; Horowitz, Daniel; Ma, Keying; Branigan, Patrick; Barnathan, Elliot S; Susulic, Vedrana S; Silkoff, Philip E; Sterk, Peter J; Baribaud, Frédéric; Airways Disease Endotyping for Personalized Therapeutics, ADEPT; Unbiased Biomarkers for the Prediction of Respiratory Disease Ou, U-BIOPRED (2016). Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study. Respiratory research, 17(1), p. 165. BioMed Central 10.1186/s12931-016-0482-9
Shaw, Dominick E; Sousa, Ana R; Fowler, Stephen J; Fleming, Louise J; Roberts, Graham; Corfield, Julie; Pandis, Ioannis; Bansal, Aruna T; Bel, Elisabeth H; Auffray, Charles; Compton, Chris H; Bisgaard, Hans; Bucchioni, Enrica; Caruso, Massimo; Chanez, Pascal; Dahlén, Barbro; Dahlen, Sven-Erik; Dyson, Kerry; Frey, Urs Peter; Geiser, Thomas; ... (2015). Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort. European respiratory journal, 46(5), pp. 1308-1321. European Respiratory Society 10.1183/13993003.00779-2015
Seumois, Grégory; Vijayanand, Pandurangan; Eisley, Christopher J; Omran, Nada; Kalinke, Lukas; North, Mal; Ganesan, Asha P; Simpson, Laura J; Hunkapiller, Nathan; Moltzahn, Felix; Woodruff, Prescott G; Fahy, John V; Erle, David J; Djukanovic, Ratko; Blelloch, Robert; Ansel, K Mark (2012). An integrated nano-scale approach to profile miRNAs in limited clinical samples. American journal of clinical and experimental immunology, 1(2), pp. 70-89. Madison, Wis.: e-Century Publishing Corporation
