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Läppchen, Tilman; Bilinska, Adrianna; Pilatis, Eirinaios; Menéndez, Elena; Imlimthan, Surachet; Moon, Euy Sung; Afshar-Oromieh, Ali; Rösch, Frank; Rominger, Axel; Gourni, Eleni (2024). Tailoring Fibroblast-Activation Protein Targeting for Theranostics: A Comparative Preclinical Evaluation of the 68Ga- and 177Lu-Labeled Monomeric and Dimeric Fibroblast-Activation Protein Inhibitors DOTA.SA.FAPi and DOTAGA.(SA.FAPi)2. Molecules, 29(13) MDPI 10.3390/molecules29133093
Escudero-Castellanos, Alondra; Kurth, Jens; Imlimthan, Surachet; Menéndez, Elena; Pilatis, Eirinaios; Moon, Euy Sung; Läppchen, Tilman; Rathke, Hendrik; Schwarzenböck, Sarah M; Krause, Bernd J; Rösch, Frank; Rominger, Axel; Gourni, Eleni (2023). Translational assessment of a DATA-functionalized FAP inhibitor with facile 68Ga-labeling at room temperature. European journal of nuclear medicine and molecular imaging, 50(11), pp. 3202-3213. Springer 10.1007/s00259-023-06285-2
D'Onofrio, Alice; Engelbrecht, Swantje; Läppchen, Tilman; Rominger, Axel; Gourni, Eleni (2023). GRPR-targeting radiotheranostics for breast cancer management. Frontiers in medicine, 10, p. 1250799. Frontiers 10.3389/fmed.2023.1250799
Birindelli, Gabriele; Drobnjakovic, Milos; Morath, Volker; Steiger, Katja; D'Alessandria, Calogero; Gourni, Eleni; Afshar-Oromieh, Ali; Weber, Wolfgang; Rominger, Axel; Eiber, Matthias; Shi, Kuangyu (2021). In silico study on radiobiological efficacy of Ac-225 and Lu-177 for PSMA-guided radiotherapy. Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2021, pp. 4497-4500. IEEE 10.1109/EMBC46164.2021.9630297
Imlimthan, Surachet; Moon, Euy Sung; Rathke, Hendrik; Afshar-Oromieh, Ali; Rösch, Frank; Rominger, Axel; Gourni, Eleni (2021). New Frontiers in Cancer Imaging and Therapy Based on Radiolabeled Fibroblast Activation Protein Inhibitors: A Rational Review and Current Progress. Pharmaceuticals, 14(10) MDPI 10.3390/ph14101023
Alberts, Ian; Niklas-Hünermund, Jan; Sachpekidis, Christos; Zacho, Helle Damgaard; Mingels, Clemens; Dijkstra, Lotte; Bohn, Karl Peter; Läppchen, Tilman; Gourni, Eleni; Rominger, Axel; Afshar-Oromieh, Ali (2021). Combination of Forced Diuresis with Additional Late Imaging in 68Ga-PSMA-11 PET/CT: Effects on Lesion Visibility and Radiotracer Uptake. Journal of nuclear medicine, 62(9), pp. 1252-1257. Society of Nuclear Medicine 10.2967/jnumed.120.257741
Birindelli, Gabriele; Drobnjakovic, Milos; Morath, Volker; Steiger, Katja; D'Alessandria, Calogero; Gourni, Eleni; Afshar-Oromieh, Ali; Weber, Wolfgang; Rominger, Axel; Eiber, Matthias; Shi, Kuangyu (2021). Is Hypoxia a Factor Influencing PSMA-Directed Radioligand Therapy?-An In Silico Study on the Role of Chronic Hypoxia in Prostate Cancer. Cancers, 13(14) MDPI AG 10.3390/cancers13143429
Hofstetter, Michael; Moon, Euy Sung; D'Angelo, Fabio; Geissbühler, Lucien; Alberts, Ian; Afshar-Oromieh, Ali; Rösch, Frank; Rominger, Axel; Gourni, Eleni (2020). Effect of the versatile bifunctional chelator AAZTA5 on the radiometal labelling properties and the in vitro performance of a gastrin releasing peptide receptor antagonist. EJNMMI radiopharmacy and chemistry, 5(1), p. 29. Springer 10.1186/s41181-020-00115-8
Alberts, Ian; Sachpekidis, Christos; Dijkstra, Lotte; Prenosil, George; Gourni, Eleni; Boxler, Silvan; Gross, Tobias; Thalmann, George; Rahbar, Kambiz; Rominger, Axel; Afshar-Oromieh, Ali (2020). The role of additional late PSMA-ligand PET/CT in the differentiation between lymph node metastases and ganglia. European journal of nuclear medicine and molecular imaging, 47(3), pp. 642-651. Springer-Verlag 10.1007/s00259-019-04552-9
Alberts, Ian; Sachpekidis, Christos; Gourni, Eleni; Boxler, Silvan; Gross, Tobias; Thalmann, George; Rahbar, Kambiz; Rominger, Axel; Afshar Oromieh, Ali (2020). Dynamic patterns of [68Ga]Ga-PSMA-11 uptake in recurrent prostate cancer lesions. European journal of nuclear medicine and molecular imaging, 47(1), pp. 160-167. Springer-Verlag 10.1007/s00259-019-04545-8
Mix, Michael; Reichel, Kathrin; Stoykow, Christian; Bartholomä, Mark; Drendel, Vanessa; Gourni, Eleni; Wetterauer, Ulrich; Schultze-Seemann, Wolfgang; Meyer, Philipp T.; Jilg, Cordula A. (2018). Performance of 111In-labelled PSMA ligand in patients with nodal metastatic prostate cancer: correlation between tracer uptake and histopathology from lymphadenectomy. European journal of nuclear medicine and molecular imaging, 45(12), pp. 2062-2070. Springer-Verlag 10.1007/s00259-018-4094-0
Popp, Ilinca; Del Pozzo, Luigi; Waser, Beatrice; Reubi, Jean Claude; Meyer, Philipp T; Maecke, Helmut R; Gourni, Eleni (2017). Approaches to improve metabolic stability of a statine-based GRP receptor antagonist. Nuclear medicine and biology, 45, pp. 22-29. Elsevier 10.1016/j.nucmedbio.2016.11.004
Gourni, Eleni; Del Pozzo, Luigi; Kheirallah, Emilie; Smerling, Christiane; Waser, Beatrice; Reubi, Jean-Claude; Paterson, Brett M; Donnelly, Paul S; Meyer, Philipp T; Maecke, Helmut R (2015). Copper-64 Labeled Macrobicyclic Sarcophagine Coupled to a GRP Receptor Antagonist Shows Great Promise for PET Imaging of Prostate Cancer. Molecular Pharmaceutics, 12(8), pp. 2781-2790. American Chemical Society 10.1021/mp500671j
Mansi, Rosalba; Abiraj, Keelara; Wang, Xuejuan; Tamma, Maria Luisa; Gourni, Eleni; Cescato, Renzo; Berndt, Sandra; Reubi, Jean Claude; Maecke, Helmut R (2015). Evaluation of three different families of bombesin receptor radioantagonists for targeted imaging and therapy of gastrin releasing peptide receptor (GRP-R) positive tumors. Journal of medicinal chemistry, 58(2), pp. 682-691. American Chemical Society 10.1021/jm5012066
Gourni, Eleni; Mansi, Rosalba; Jamous, Mazen; Waser, Beatrice; Smerling, Christiane; Burian, Antje; Buchegger, Franz; Reubi, Jean-Claude; Maecke, Helmut R (2014). N-terminal modifications improve the receptor affinity and pharmacokinetics of radiolabeled peptidic gastrin-releasing peptide receptor antagonists: examples of 68Ga- and 64Cu-labeled peptides for PET imaging. Journal of nuclear medicine, 55(10), pp. 1719-1725. Society of Nuclear Medicine 10.2967/jnumed.114.141242
Jamous, Mazen; Tamma, Maria L; Gourni, Eleni; Waser, Beatrice; Reubi, Jean-Claude; Maecke, Helmut R; Mansi, Rosalba (2014). PEG spacers of different length influence the biological profile of bombesin-based radiolabeled antagonists. Nuclear medicine and biology, 41(6), pp. 464-470. Elsevier 10.1016/j.nucmedbio.2014.03.014
Gourni, Eleni; Waser, Beatrice; Clerc, Pascal; Fourmy, Daniel; Reubi, Jean-Claude; Maecke, Helmut R (2014). The Glucose-Dependent Insulinotropic Polypeptide Receptor: A Novel Target for Neuroendocrine Tumor Imaging-First Preclinical Studies. Journal of nuclear medicine, 55(6), pp. 976-982. Society of Nuclear Medicine 10.2967/jnumed.113.133744
Mikkola, Kirsi; Yim, Cheng-Bin; Fagerholm, Veronica; Ishizu, Tamiko; Elomaa, Viki-Veikko; Rajander, Johan; Jurttila, Jori; Saanijoki, Tiina; Tolvanen, Tuula; Tirri, Marko; Gourni, Eleni; Béhé, Martin; Gotthardt, Martin; Reubi, Jean-Claude; Mäcke, Helmut; Roivainen, Anne; Solin, Olof; Nuutila, Pirjo (2014). Erratum to: (64)Cu- and (68)Ga-Labelled [Nle (14),Lys (40)(Ahx-NODAGA)NH 2]-Exendin-4 for Pancreatic Beta Cell Imaging in Rats. Molecular imaging and biology, 16(2), p. 293. Springer 10.1007/s11307-013-0700-5
Mikkola, Kirsi; Kirsi, Mikkola; Yim, Cheng-Bin; Cheng-Bin, Yim; Fagerholm, Veronica; Veronica, Fagerholm; Ishizu, Tamiko; Tamiko, Ishizu; Elomaa, Viki-Veikko; Viki-Veikko, Elomaa; Rajander, Johan; Johan, Rajander; Jurttila, Jori; Jori, Jurttila; Saanijoki, Tiina; Tiina, Saanijoki; Tolvanen, Tuula; Tuula, Tolvanen; Tirri, Marko; Marko, Tirri; ... (2014). 64Cu- and 68Ga-labelled [Nle(14),Lys(40)(Ahx-NODAGA)NH2]-exendin-4 for pancreatic beta cell imaging in rats. Molecular imaging and biology, 16(2), pp. 255-263. Springer 10.1007/s11307-013-0691-2
Imlimthan, Surachet; Menéndez, Elena; Escudero-Castellanos, Alondra; Moon, Euy Sung; Läppchen, Tilman; Rathke, Hendrik; Afshar-Oromieh, Ali; Roesch, Frank; Rominger, Axel; Gourni, Eleni (2022). Investigation of 68Ga/177Lu-labeled FAP-based inhibitor for diagnostic and therapeutic applications. Nuclear medicine and biology, 108-109, S56-S57. Elsevier 10.1016/S0969-8051(22)00147-0
Escudero-Castellanos, Alondra; Imlimthan, Surachet; Menéndez, Elena; Moon, Euy Sung; Läppchen, Tilman; Rathke, Hendrik; Afshar Oromieh, Ali; Roesch, Frank; Rominger, Axel; Gourni, Eleni (2022). Tumor stroma diagnostic imaging by a 68Ga-coupled small-molecule fibroblast activation protein (FAP) inhibitor: first pre-clinical data. Nuclear medicine and biology, 108-109, S186-S187. Elsevier 10.1016/S0969-8051(22)00388-2
