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Chicca, Andrea; Bátora, Daniel; Ullmer, Christoph; Caruso, Antonello; Grüner, Sabine; Fingerle, Jürgen; Hartung, Thomas; Degen, Roland; Müller, Matthias; Grether, Uwe; Pacher, Pal; Gertsch, Jürg (2024). A Highly Potent, Orally Bioavailable Pyrazole-Derived Cannabinoid CB2 Receptor- Selective Full Agonist for In Vivo Studies. ACS pharmacology & translational science, 7(8), pp. 2424-2438. ACS Publications 10.1021/acsptsci.4c00269
Haider, Ahmed; Wang, Lu; Gobbi, Luca; Li, Yinlong; Chaudhary, Ahmad; Zhou, Xin; Chen, Jiahui; Zhao, Chunyu; Rong, Jian; Xiao, Zhiwei; Hou, Lu; Elghazawy, Nehal H; Sippl, Wolfgang; Davenport, April T; Daunais, James B; Ahmed, Hazem; Crowe, Ron; Honer, Michael; Rominger, Axel; Grether, Uwe; ... (2023). Evaluation of [18F]RoSMA-18-d6 as a CB2 PET Radioligand in Nonhuman Primates. ACS chemical neuroscience, 14(20), pp. 3752-3760. American Chemical Society 10.1021/acschemneuro.3c00222
Maccarrone, Mauro; Di Marzo, Vincenzo; Gertsch, Juerg; Grether, Uwe; Howlett, Allyn C; Hua, Tian; Makriyannis, Alexandros; Piomelli, Daniele; Ueda, Natsuo; van der Stelt, Mario (2023). Goods and bads of endocannabinoid system as a therapeutic target: Lessons learned after 30 years. Pharmacological reviews, 75(5), pp. 885-958. American Society for Pharmacology and Experimental Therapeutics 10.1124/pharmrev.122.000600
Kemble, Alicia M; Hornsperger, Benoit; Ruf, Iris; Richter, Hans; Benz, Jörg; Kuhn, Bernd; Heer, Dominik; Wittwer, Matthias; Engelhardt, Britta; Grether, Uwe; Collin, Ludovic (2022). A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature. PLoS ONE, 17(9), e0268590. Public Library of Science 10.1371/journal.pone.0268590
Gazzi, Thais; Brennecke, Benjamin; Atz, Kenneth; Korn, Claudia; Sykes, David; Forn-Cuni, Gabriel; Pfaff, Patrick; Sarott, Roman C; Westphal, Matthias V; Mostinski, Yelena; Mach, Leonard; Wasinska-Kalwa, Malgorzata; Weise, Marie; Hoare, Bradley L; Miljuš, Tamara; Mexi, Maira; Roth, Nicolas; Koers, Eline J; Guba, Wolfgang; Alker, André; ... (2022). Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe. Chemical Science, 13(19), pp. 5539-5545. The Royal Society of Chemistry 10.1039/d1sc06659e
Sarott, Roman C; Westphal, Matthias V; Pfaff, Patrick; Korn, Claudia; Sykes, David A; Gazzi, Thais; Brennecke, Benjamin; Atz, Kenneth; Weise, Marie; Mostinski, Yelena; Hompluem, Pattarin; Koers, Eline; Miljuš, Tamara; Roth, Nicolas J; Asmelash, Hermon; Vong, Man C; Piovesan, Jacopo; Guba, Wolfgang; Rufer, Arne C; Kusznir, Eric A; ... (2020). Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells. Journal of the American Chemical Society, 142(40), pp. 16953-16964. American Chemical Society 10.1021/jacs.0c05587
Soethoudt, Marjolein; Grether, Uwe; Fingerle, Jürgen; Grim, Travis W; Fezza, Filomena; de Petrocellis, Luciano; Ullmer, Christoph; Rothenhäusler, Benno; Perret, Camille; van Gils, Noortje; Finlay, David; MacDonald, Christa; Chicca, Andrea; Gens, Marianela Dalghi; Stuart, Jordyn; de Vries, Henk; Mastrangelo, Nicolina; Xia, Lizi; Alachouzos, Georgios; Baggelaar, Marc P; ... (2017). Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity. Nature communications, 8(13958), p. 13958. Nature Publishing Group 10.1038/ncomms13958
Chicca, Andrea; Batora, Daniel; Ullmer, Christoph; Caruso, Antonello; Fingerle, Jürgen; Hartung, Thomas; Degen, Roland; Müller, Matthias; Grether, Uwe; Pacher, Pal; Gertsch, Jürg (29 April 2024). A highly potent, orally bioavailable pyrazole-derived cannabinoid CB2 receptor-selective full agonist for in vivo studies. (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2024.04.26.591311
