Hänggeli, Kai Pascal Alexander

Boubaker, Ghalia; Bernal, Alice; Vigneswaran, Anitha; Imhof, Dennis; Ferreira de Sousa, Maria Cristina; Hänggeli, Kai Pascal Alexander; Haudenschild, Noé; Furrer, Julien; Păunescu, Emilia; Desiatkina, Oksana; Hemphill, Andrew (2024). In vitro and in vivo activities of a trithiolato-diRuthenium complex conjugated with sulfadoxine against the apicomplexan parasite Toxoplasma gondii. International journal for parasitology. Drugs and drug resistance, 25(100544), p. 100544. Elsevier 10.1016/j.ijpddr.2024.100544

Ferreira de Sousa, Maria Cristina; Imhof, Dennis; Hänggeli, Kai Pascal Alexander; Choi, Ryan; Hulverson, Matthew A; Arnold, Samuel L M; Van Voorhis, Wesley C; Fan, Erkang; Roberto, Sánchez-Sánchez; Ortega-Mora, Luis M; Hemphill, Andrew (2024). Efficacy of the bumped kinase inhibitor BKI-1708 against the cyst-forming apicomplexan parasites Toxoplasma gondii and Neospora caninum in vitro and in experimentally infected mice. International journal for parasitology. Drugs and drug resistance, 25, p. 100553. Elsevier 10.1016/j.ijpddr.2024.100553

Imhof, Dennis; Hänggeli, Kai Pascal Alexander; Ferreira de Sousa, Maria Cristina; Vigneswaran, Anitha; Hofmann, Larissa; Amdouni, Yosra; Boubaker, Ghalia; Müller, Joachim; Hemphill, Andrew (2024). Working towards the development of vaccines and chemotherapeutics against neosporosis—With all of its ups and downs—Looking ahead. Advances in Parasitology, 124, pp. 91-154. Elsevier 10.1016/bs.apar.2024.01.001

Rico-San Román, Laura; Hänggeli, Kai Pascal Alexander; Hemphill, Andrew; Horcajo, Pilar; Collantes-Fernández, Esther; Ortega-Mora, Luis Miguel; Boubaker, Ghalia (2024). TaqMan-quantitative PCR assays applied in Neospora caninum knock-outs generated through CRISPR-Cas9 allow to determine the copy numbers of integrated dihydrofolate reductase-thymidylate synthase drug selectable markers. Frontiers in cellular and infection microbiology, 14(1419209) Frontiers 10.3389/fcimb.2024.1419209

Schlange, Carling; Müller, Joachim; Imhof, Dennis; Hänggeli, Kai Pascal Alexander; Boubaker, Ghalia; Ortega-Mora, Luis-Miguel; Wong, Ho Ning; Haynes, Richard K; Van Voorhis, Wesley C; Hemphill, Andrew (2023). Single and combination treatment of Toxoplasma gondii infections with a bumped kinase inhibitor and artemisone in vitro and with artemiside in experimentally infected mice. Experimental parasitology, 255(108655), p. 108655. Elsevier 10.1016/j.exppara.2023.108655

Hänggeli, Kai Pascal Alexander; Hemphill, Andrew; Müller, Norbert; Heller, Manfred; Uldry, Anne-Christine; Braga-Lagache, Sophie; Müller, Joachim; Boubaker, Ghalia (2023). Comparative Proteomic Analysis of Toxoplasma gondii RH Wild-Type and Four SRS29B (SAG1) Knock-Out Clones Reveals Significant Differences between Individual Strains. International journal of molecular sciences, 24(13) MDPI 10.3390/ijms241310454

Ramseier, Jessica; Imhof, Dennis; Hänggeli, Kai Pascal Alexander; Anghel, Nicoleta; Boubaker, Ghalia; Beteck, Richard M; Ortega-Mora, Luis-Miguel; Haynes, Richard K; Hemphill, Andrew (2023). In Vitro versus in Mice: Efficacy and Safety of Decoquinate and Quinoline-O-Carbamate Derivatives against Experimental Infection with Neospora caninum Tachyzoites. Pathogens, 12(3) MDPI AG 10.3390/pathogens12030447

Imhof, Dennis; Pownall, William; Hänggeli, Kai Pascal Alexander; Monney, Camille; Rico-San Román, Laura; Ortega-Mora, Luis-Miguel; Forterre, Franck; Oevermann, Anna; Hemphill, Andrew (2023). Immunization with a Multivalent Listeria monocytogenes Vaccine Leads to a Strong Reduction in Vertical Transmission and Cerebral Parasite Burden in Pregnant and Non-Pregnant Mice Infected with Neospora caninum. Vaccines, 11(1), p. 156. MDPI 10.3390/vaccines11010156

Hänggeli, Kai Pascal Alexander; Hemphill, Andrew; Müller, Norbert; Schimanski, Bernd; Olias, Philipp; Müller, Joachim; Boubaker, Ghalia (2022). Single- and duplex TaqMan-quantitative PCR for determining the copy numbers of integrated selection markers during site-specific mutagenesis in Toxoplasma gondii by CRISPR-Cas9. PLoS ONE, 17(9), e0271011. Public Library of Science 10.1371/journal.pone.0271011