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Di Stefano, Miriana; Masoni, Samuele; Bononi, Giulia; Poli, Giulio; Galati, Salvatore; Gado, Francesca; Manzi, Simone; Vagaggini, Chiara; Brai, Annalaura; Caligiuri, Isabella; Asif, Kanwal; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Sodi, Andrea; Di Bussolo, Valeria; Minutolo, Filippo; Meier, Philip; Gertsch, Jürg; Granchi, Carlotta; ... (2024). Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors. European journal of medicinal chemistry, 263(115916), p. 115916. Elsevier 10.1016/j.ejmech.2023.115916
Bononi, Giulia; Di Stefano, Miriana; Poli, Giulio; Ortore, Gabriella; Meier, Philip; Masetto, Francesca; Caligiuri, Isabella; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Avan, Amir; Giovannetti, Elisa; Vagaggini, Chiara; Brai, Annalaura; Dreassi, Elena; Valoti, Massimo; Minutolo, Filippo; Granchi, Carlotta; Gertsch, Jürg and Tuccinardi, Tiziano (2022). Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives. Journal of medicinal chemistry, 65(10), pp. 7118-7140. American Chemical Society 10.1021/acs.jmedchem.1c01806
Granchi, Carlotta; Bononi, Giulia; Ferrisi, Rebecca; Gori, Eleonora; Mantini, Giulia; Glasmacher, Sandra; Poli, Giulio; Palazzolo, Stefano; Caligiuri, Isabella; Rizzolio, Flavio; Canzonieri, Vincenzo; Perin, Tiziana; Gertsch, Jürg; Sodi, Andrea; Giovannetti, Elisa; Macchia, Marco; Minutolo, Filippo; Tuccinardi, Tiziano; Chicca, Andrea (2021). Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors. European journal of medicinal chemistry, 209, p. 112857. Elsevier 10.1016/j.ejmech.2020.112857
Granchi, Carlotta; Lapillo, Margherita; Glasmacher, Sandra; Bononi, Giulia; Licari, Cristina; Poli, Giulio; El Boustani, Maguie; Caligiuri, Isabella; Rizzolio, Flavio; Gertsch, Jürg; Macchia, Marco; Minutolo, Filippo; Tuccinardi, Tiziano; Chicca, Andrea (2019). Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor. Journal of medicinal chemistry, 62(4), pp. 1932-1958. American Chemical Society 10.1021/acs.jmedchem.8b01483
Bononi, Giulia; Granchi, Carlotta; Lapillo, Margherita; Giannotti, Massimiliano; Nieri, Daniela; Fortunato, Serena; Boustani, Maguie El; Caligiuri, Isabella; Poli, Giulio; Carlson, Kathryn E; Kim, Sung Hoon; Macchia, Marco; Martinelli, Adriano; Rizzolio, Flavio; Chicca, Andrea; Katzenellenbogen, John A; Minutolo, Filippo; Tuccinardi, Tiziano (2018). Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors. European journal of medicinal chemistry, 157, pp. 817-836. Elsevier Masson SAS 10.1016/j.ejmech.2018.08.038
Aghazadeh Tabrizi, Mojgan; Baraldi, Pier Giovanni; Baraldi, Stefania; Ruggiero, Emanuela; De Stefano, Lucia; Rizzolio, Flavio; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Chicca, Andrea; Lapillo, Margherita; Gertsch, Jürg; Manera, Clementina; Macchia, Marco; Martinelli, Adriano; Granchi, Carlotta; Minutolo, Filippo; Tuccinardi, Tiziano (2018). Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors. Journal of medicinal chemistry, 61(3), pp. 1340-1354. American Chemical Society 10.1021/acs.jmedchem.7b01845
