Osthoff, Michael

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Journal Article

Hermann, Laura; Schöning, Verena; Dräger, Sarah; Rentsch, Katharina; Moser, Stephan; Gürtler, Nicolas; Sendi, Parham; Osthoff, Michael; Hammann, Felix (2024). Population pharmacokinetics of flucloxacillin as intermittent bolus infusion in patients with Staphylococcus aureus bloodstream infection. The journal of antimicrobial chemotherapy, 79(8), pp. 2031-2039. Oxford University Press 10.1093/jac/dkae207

Urwyler, Pascal; Leimbacher, Marina; Charitos, Panteleimon; Moser, Stephan; Heijnen, Ingmar A F M; Trendelenburg, Marten; Thoma, Reto; Sumer, Johannes; Camacho-Ortiz, Adrián; Bacci, Marcelo R; Huber, Lars C; Stüssi-Helbling, Melina; Albrich, Werner C; Sendi, Parham; Osthoff, Michael (2023). Recombinant C1 inhibitor in the prevention of severe COVID-19: a randomized, open-label, multi-center phase IIa trial. Frontiers in immunology, 14(1255292), p. 1255292. Frontiers Research Foundation 10.3389/fimmu.2023.1255292

Urwyler, Pascal; Moser, Stephan; Trendelenburg, Marten; Sendi, Parham; Osthoff, Michael (2022). Targeting thromboinflammation in COVID-19 - A narrative review of the potential of C1 inhibitor to prevent disease progression. Molecular immunology, 150, pp. 99-113. Elsevier 10.1016/j.molimm.2022.08.008

Adam, Kai-Manuel; Osthoff, Michael; Lamoth, Frédéric; Conen, Anna; Erard, Véronique; Boggian, Katia; Schreiber, Peter W; Zimmerli, Stefan; Bochud, Pierre-Yves; Neofytos, Dionysios; Fleury, Mapi; Fankhauser, Hans; Goldenberger, Daniel; Mühlethaler, Konrad; Riat, Arnaud; Zbinden, Reinhard; Kronenberg, Andreas; Quiblier, Chantal; Marchetti, Oscar and Khanna, Nina (2021). Trends of the Epidemiology of Candidemia in Switzerland: A 15-Year FUNGINOS Survey. Open Forum Infectious Diseases, 8(10), ofab471. Oxford University Press 10.1093/ofid/ofab471

Moser, Stephan; Rehm, Sophia; Guertler, Nicolas; Hinic, Vladimira; Dräger, Sarah; Bassetti, Stefano; Rentsch, Katharina M; Sendi, Parham; Osthoff, Michael (2021). Probability of pharmacological target attainment with flucloxacillin in Staphylococcus aureus bloodstream infection: a prospective cohort study of unbound plasma and individual MICs. The journal of antimicrobial chemotherapy, 76(7), pp. 1845-1854. Oxford University Press 10.1093/jac/dkab089

Mari, Alfredo; Roloff, Tim; Stange, Madlen; Søgaard, Kirstine K; Asllanaj, Erblin; Tauriello, Gerardo; Alexander, Leila Tamara; Schweitzer, Michael; Leuzinger, Karoline; Gensch, Alexander; Martinez, Aurélien E; Bielicki, Julia; Pargger, Hans; Siegemund, Martin; Nickel, Christian H; Bingisser, Roland; Osthoff, Michael; Bassetti, Stefano; Sendi, Parham; Battegay, Manuel; ... (2021). Global Genomic Analysis of SARS-CoV-2 RNA Dependent RNA Polymerase Evolution and Antiviral Drug Resistance. Microorganisms, 9(5) MDPI 10.3390/microorganisms9051094

Urwyler, Pascal; Charitos, Panteleimon; Moser, Stephan; Heijnen, Ingmar A F M; Trendelenburg, Marten; Thoma, Reto; Sumer, Johannes; Camacho-Ortiz, Adrián; Bacci, Marcelo R; Huber, Lars C; Stüssi-Helbling, Melina; Albrich, Werner C; Sendi, Parham; Osthoff, Michael (2021). Recombinant human C1 esterase inhibitor (conestat alfa) in the prevention of severe SARS-CoV-2 infection in hospitalized patients with COVID-19: A structured summary of a study protocol for a randomized, parallel-group, open-label, multi-center pilot trial (PROTECT-COVID-19). Trials, 22(1), p. 1. BioMed Central 10.1186/s13063-020-04976-x

Marzolini, Catia; Stader, Felix; Stoeckle, Marcel; Franzeck, Fabian; Egli, Adrian; Bassetti, Stefano; Hollinger, Alexa; Osthoff, Michael; Weisser, Maja; Gebhard, Caroline E; Baettig, Veronika; Geenen, Julia; Khanna, Nina; Tschudin-Sutter, Sarah; Mueller, Daniel; Hirsch, Hans H; Battegay, Manuel; Sendi, Parham (2020). Effect of Systemic Inflammatory Response to SARS-CoV-2 on Lopinavir and Hydroxychloroquine Plasma Concentrations. Antimicrobial agents and chemotherapy, 64(9) American Society for Microbiology 10.1128/AAC.01177-20

Wójtowicz, Agnieszka; Bibert, Stéphanie; Taffé, Patrick; Bernasconi, Enos; Furrer, Hansjakob; Günthard, Huldrych F; Hoffmann, Matthias; Osthoff, Michael; Cavassini, Matthias; Bochud, Pierre-Yves (2019). IL-4 polymorphism influences susceptibility to Pneumocystis jirovecii pneumonia in HIV-positive patients. AIDS, 33(11), pp. 1719-1727. Lippincott Williams & Wilkins 10.1097/QAD.0000000000002283

Seth-Smith, Helena M B; Imkamp, Frank; Tagini, Florian; Cuénod, Aline; Hömke, Rico; Jahn, Kathleen; Tschacher, Anne; Grendelmeier, Peter; Bättig, Veronika; Erb, Stefan; Reinhard, Miriam; Rütimann, Gottfried; Borrell, Sonia; Gagneux, Sebastien; Casanova, Carlo; Droz, Sara; Osthoff, Michael; Tamm, Michael; Nübel, Ulrich; Greub, Gilbert; ... (2019). Discovery and Characterization of Mycobacterium basiliense sp. nov., a Nontuberculous Mycobacterium Isolated From Human Lungs. Frontiers in Microbiology, 9(3184), p. 3184. Frontiers 10.3389/fmicb.2018.03184

Bibert, Stéphanie; Wójtowicz, Agnieszka; Taffé, Patrick; Tarr, Philip E; Bernasconi, Enos; Furrer, Hansjakob; Günthard, Huldrych F; Hoffmann, Matthias; Kaiser, Laurent; Osthoff, Michael; Fellay, Jacques; Cavassini, Matthias; Bochud, Pierre-Yves (2018). Interferon lambda 3/4 polymorphisms are associated with AIDS-related Kaposi's sarcoma. AIDS, 32(18), pp. 2759-2765. Lippincott Williams & Wilkins 10.1097/QAD.0000000000002004

Osthoff, Michael; Wojtowicz, Agnieszka; Tissot, Frederic; Jørgensen, Clara; Thiel, Steffen; Zimmerli, Stefan; Marchetti, Oscar; Khanna, Nina; Bochud, Pierre-Yves; Trendelenburg, Marten (2016). Association of lectin pathway proteins with intra-abdominal Candida infection in high-risk surgical intensive-care unit patients. A prospective cohort study within the fungal infection network of Switzerland. Journal of infection, 72(3), pp. 377-385. Elsevier 10.1016/j.jinf.2015.12.011

Osthoff, Michael; Egli, Adrian; Schürch, Nadia; Leib, Stephen; Mihatsch, Felix; Frei, Reno (2015). Ein nicht alltägliches türkisches Souvenir. Schweizerisches Medizin-Forum SMF / Swiss medical forum / Forum médical suisse FMS, 15(25), pp. 611-613. EMH Editores Medicorum Helveticorum

Bibert, Stéphanie; Wojtowicz, Agnieszka; Taffé, Patrick; Manuel, Oriol; Bernasconi, Enos; Furrer, Hansjakob; Günthard, Huldrych F; Hoffmann, Matthias; Kaiser, Laurent; Osthoff, Michael; Cavassini, Matthias; Bochud, Pierre-Yves (2014). The IFNL3/4 ΔG variant increases susceptibility to cytomegalovirus retinitis among HIV-infected patients. AIDS, 28(13), pp. 1885-1889. Lippincott Williams & Wilkins 10.1097/QAD.0000000000000379

Egli, Adrian; Schäfer, Juliane; Osthoff, Michael; Thiel, Steffen; Mikkelsen, Christina; Rauch, Andri; Hirsch, Hans H; Bucher, Heiner C; Young, James; Jensenius, Jens C; Battegay, Manuel; Trendelenburg, Marten; Swiss HIV Cohort Study, (2012). Low levels of mannan-binding lectin or ficolins are not associated with an increased risk of cytomegalovirus disease in HIV-infected patients. PLoS ONE, 8(1), e51983. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0051983

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