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Stenman, Sebastian; Bétrisey, Sylvain; Vainio, Paula; Huvila, Jutta; Lundin, Mikael; Linder, Nina; Schmitt, Anja; Perren, Aurel; Dettmer, Matthias S; Haglund, Caj; Arola, Johanna; Lundin, Johan (2024). External validation of a deep learning-based algorithm for detection of tall cells in papillary thyroid carcinoma: A multicenter study. Journal of pathology informatics, 15(100366) Elsevier 10.1016/j.jpi.2024.100366
Karamitopoulou, Eva; Wenning, Anna Silvia; Acharjee, Animesh; Aeschbacher, Pauline; Marinoni, Ilaria; Zlobec, Inti; Gloor, Beat; Perren, Aurel (2024). Spatial heterogeneity of immune regulators drives dynamic changes of local immune responses, affecting disease outcomes in pancreatic cancer. Clinical cancer research, 30(18), pp. 4215-4226. American Association for Cancer Research 10.1158/1078-0432.CCR-24-0368
Elvebakken, Hege; Venizelos, Andreas; Perren, Aurel; Couvelard, Anne; Lothe, Inger Marie B; Hjortland, Geir O; Myklebust, Tor Å; Svensson, Johanna; Garresori, Herish; Kersten, Christian; Hofsli, Eva; Detlefsen, Sönke; Vestermark, Lene W; Knappskog, Stian; Sorbye, Halfdan (2024). Treatment outcome according to genetic tumour alterations and clinical characteristics in digestive high-grade neuroendocrine neoplasms. British journal of cancer, 131(4), pp. 676-684. Springer Nature 10.1038/s41416-024-02773-w
Moser, Elisa; Ura, Ayako; Vogel, Loreen; Steiger, Katja; Mogler, Carolin; Evert, Matthias; Märkl, Bruno; Scheidhauer, Klemens; Martignoni, Marc; Friess, Helmut; von Werder, Alexander; Marinoni, Ilaria; Perren, Aurel; Klöppel, Günter; Kasajima, Atsuko (2024). ARX, PDX1, ISL1 and CDX2 expression distinguishes five subgroups of PanNETs with correlations to histology, hormone expression and outcome. (In Press). Modern pathology, 37(11), p. 100595. Elsevier 10.1016/j.modpat.2024.100595
Chouchane, Aziz; Kirchner, Philipp; Marinoni, Ilaria; Sticová, Eva; Jirásek, Tomáš; Perren, Aurel (2024). Pancreatic Neuroendocrine Microtumors (WHO 2022) Are Not Always Low-Grade Neoplasms: A Case with a Highly Increased Proliferation Rate. Endocrine pathology, 35(2), pp. 147-153. Springer 10.1007/s12022-024-09802-7
Bräutigam, Konstantin; Nesti, Cédric; Riss, Philipp; Scheuba, Christian; Niederle, Bruno; Grob, Tobias; Di Domenico, Annunziata; Neuenschwander, Maja; Mazal, Peter; Köhn, Nastassja; Trepp, Roman; Perren, Aurel; Kaderli, Reto M (2024). Syndromic MEN1 parathyroid adenomas consist of both subclonal nodules and clonally independent tumors. Virchows Archiv, 484(5), pp. 789-798. Springer 10.1007/s00428-023-03730-3
April-Monn, Simon L; Kirchner, Philipp; Detjen, Katharina; Bräutigam, Konstantin; Trippel, Mafalda A; Grob, Tobias; Statzer, Cyril; Maire, Renaud S; Kollár, Attila; Chouchane, Aziz; Kunze, Catarina A; Horst, David; Sadowski, Martin C; Schrader, Jörg; Marinoni, Ilaria; Wiedenmann, Bertram; Perren, Aurel (2024). Patient derived tumoroids of high grade neuroendocrine neoplasms for more personalized therapies. NPJ precision oncology, 8(59) Springer Nature 10.1038/s41698-024-00549-2
Bräutigam, Konstantin; Chouchane, Aziz; Konukiewitz, Björn; Perren, Aurel (2024). [Practical application of immunohistochemistry in pancreatic neuroendocrine neoplasms : Tips and pitfalls]. Pathologie, 45(1), pp. 35-41. Springer 10.1007/s00292-023-01276-4
Schaad, Nicole; Berezowska, Sabina; Perren, Aurel; Hewer, Ekkehard Walter (2024). Impact of template-based synoptic reporting on completeness of surgical pathology reports. Virchows Archiv, 484(1), pp. 31-36. Springer 10.1007/s00428-023-03533-6
Frei, Ana Leni; Oberson, Raphaël; Baumann, Elias; Perren, Aurel; Grobholz, Rainer; Lugli, Alessandro; Dawson, Heather; Abbet, Christian; Lertxundi, Ibai; Reinhard, Stefan; Mookhoek, Aart; Feichtinger, Johann; Sarro, Rossella; Gadient, Gallus; Dommann-Scherrer, Corina; Barizzi, Jessica; Berezowska, Sabina; Glatz, Katharina; Dertinger, Susanne; Banz, Yara; ... (2023). Pathologist computer-aided diagnostic scoring of tumor cell fraction: A Swiss national study. Modern pathology, 36(12), p. 100335. Springer Nature 10.1016/j.modpat.2023.100335
Morken, Siren; Langer, Seppo W; Sundlöv, Anna; Vestermark, Lene Weber; Ladekarl, Morten; Hjortland, Geir Olav; Svensson, Johanna B; Tabaksblat, Elizaveta Mitkina; Haslerud, Torjan Magne; Assmus, Jörg; Detlefsen, Sönke; Couvelard, Anne; Perren, Aurel; Sorbye, Halfdan (2023). Phase II study of everolimus and temozolomide as first-line treatment in metastatic high-grade gastroenteropancreatic neuroendocrine neoplasms. British journal of cancer, 129(12), pp. 1930-1939. Nature Publishing Group 10.1038/s41416-023-02462-0
Kos-Kudła, Beata; Castaño, Justo P; Denecke, Timm; Grande, Enrique; Kjaer, Andreas; Koumarianou, Anna; de Mestier, Louis; Partelli, Stefano; Perren, Aurel; Stättner, Stefan; Valle, Juan W; Fazio, Nicola (2023). European Neuroendocrine Tumour Society (ENETS) 2023 guidance paper for nonfunctioning pancreatic neuroendocrine tumours. Journal of neuroendocrinology, 35(12), e13343. Wiley-Blackwell 10.1111/jne.13343
Venizelos, Andreas; Sorbye, Halfdan; Elvebakken, Hege; Perren, Aurel; Lothe, Inger Marie B; Couvelard, Anne; Hjortland, Geir Olav; Sundlöv, Anna; Svensson, Johanna; Garresori, Harrish; Kersten, Christian; Hofsli, Eva; Detlefsen, Sönke; Vestermark, Lene W; Ladekarl, Morten; Tabaksblat, Elizaveta Mitkina; Knappskog, Stian (2023). Germline pathogenic variants in patients with high-grade gastroenteropancreatic neuroendocrine neoplasms. Endocrine-related cancer, 30(10) BioScientifica 10.1530/ERC-23-0057
Sampaio, Paulo; Lopez-Antuña, Maria; Storni, Federico; Wicht, Jonatan; Sökeland, Greta; Wartenberg, Martin; Márquez Neila, Pablo; Candinas, Daniel; Demory, Brice-Olivier; Perren, Aurel; Sznitman, Raphael (2023). Müller matrix polarimetry for pancreatic tissue characterization. Scientific Reports, 13(1), p. 16417. Nature Publishing Group 10.1038/s41598-023-43195-7
Dettmer, Matthias S; Hürlimann, Sandra; Scheuble, Lukas; Vassella, Erik; Perren, Aurel; Wicke, Corinna (2023). Cribriform Morular Thyroid Carcinoma - Ultimobranchial Pouch-Related? Deep Molecular Insights of a Unique Case. Endocrine pathology, 34(3), pp. 342-348. Springer 10.1007/s12022-023-09775-z
Karamitopoulou, Eva; Wenning, Anna Silvia; Acharjee, Animesh; Zlobec, Inti; Aeschbacher, Pauline; Perren, Aurel; Gloor, Beat (2023). Spatially restricted tumour-associated and host-associated immune drivers correlate with the recurrence sites of pancreatic cancer. Gut, 72(8), pp. 1523-1533. BMJ Publishing Group 10.1136/gutjnl-2022-329371
Hofland, Johannes; Falconi, Massimo; Christ, Emanuel; Castaño, Justo P; Faggiano, Antongiulio; Lamarca, Angela; Perren, Aurel; Petrucci, Simona; Prasad, Vikas; Ruszniewski, Philippe; Thirlwell, Christina; Vullierme, Marie-Pierre; Welin, Staffan; Bartsch, Detlef K (2023). European Neuroendocrine Tumor Society 2023 guidance paper for functioning pancreatic neuroendocrine tumour syndromes. Journal of neuroendocrinology, 35(8), e13318. Wiley-Blackwell 10.1111/jne.13318
Christ, Emanuel; Iacovazzo, Donato; Korbonits, Marta; Perren, Aurel (2023). Insulinomatosis - new aspects. Endocrine-related cancer, 30(6) BioScientifica 10.1530/ERC-22-0327
Seubnooch, Patcharamon; Montani, Matteo; Tsouka, Sofia; Claude, Emmanuelle; Rafiqi, Umara; Perren, Aurel; Dufour, Jean-Francois; Masoodi, Mojgan (2023). Characterisation of hepatic lipid signature distributed across the liver zonation using mass spectrometry imaging. JHEP reports, 5(6), p. 100725. Elsevier 10.1016/j.jhepr.2023.100725
Eshmuminov, Dilmurodjon; Studer, Debora J; Lopez Lopez, Victor; Schneider, Marcel André; Lerut, Jan; Lo, Mary; Sher, Linda; Musholt, Thomas Johannes; Lozan, Oana; Bouzakri, Nabila; Sposito, Carlo; Miceli, Rosalba; Barat, Shoma; Morris, David; Oehler, Helga; Schreckenbach, Teresa; Husen, Peri; Rosen, Charles B; Gores, Gregory J; Masui, Toshihiko; ... (2023). Controversy Over Liver Transplantation or Resection for Neuroendocrine Liver Metastasis: Tumor Biology Cuts the Deal. Annals of surgery, 277(5), e1063-e1071. Wolters Kluwer Health 10.1097/SLA.0000000000005663
Khan, Amjad; Brouwer, Nelleke; Blank, Annika; Müller, Felix; Soldini, Davide; Noske, Aurelia; Gaus, Elisabeth; Brandt, Simone; Nagtegaal, Iris; Dawson, Heather; Thiran, Jean-Philippe; Perren, Aurel; Lugli, Alessandro; Zlobec, Inti (2023). Computer-Assisted Diagnosis of Lymph Node Metastases in Colorectal Cancers Using Transfer Learning With an Ensemble Model. Modern pathology, 36(5), p. 100118. Springer Nature 10.1016/j.modpat.2023.100118
Kaderli, Reto M; Nesti, Cédric; Bräutigam, Konstantin; Zwahlen, Marcel; Perren, Aurel (2023). Omitting hemicolectomy for patients with appendiceal neuroendocrine tumours of 1-2 cm - Authors' reply. The lancet oncology, 24(5), e190-e191. Elsevier 10.1016/S1470-2045(23)00114-6
Skoworonska, Magdalena; Blank, Annika; Centeno, Irene; Hammer, Caroline; Perren, Aurel; Zlobec, Inti; Rau, Tilman T (2023). Real-life data from standardized preanalytical coding (SPREC) in tissue biobanking and its dual use for sample characterization and process optimization. The journal of pathology: clinical research, 9(2), pp. 137-148. Wiley 10.1002/cjp2.305
Schiavo Lena, Marco; Partelli, Stefano; Andreasi, Valentina; Muffatti, Francesca; Redegalli, Miriam; Brunetto, Emanuela; Maghini, Beatrice; Falke, Monika; Cangi, Maria Giulia; Perren, Aurel; Falconi, Massimo; Doglioni, Claudio (2023). Infiltrative Growth Predicts the Risk of Recurrence After Surgery in Well-Differentiated Non-Functioning Pancreatic Neuroendocrine Tumors. Endocrine pathology, 34(1), pp. 142-155. Springer 10.1007/s12022-022-09745-x
Nesti, Cédric; Bräutigam, Konstantin; Benavent, Marta; Bernal, Laura; Boharoon, Hessa; Botling, Johan; Bouroumeau, Antonin; Brcic, Iva; Brunner, Maximilian; Cadiot, Guillaume; Camara, Maria; Christ, Emanuel; Clerici, Thomas; Clift, Ashley K; Clouston, Hamish; Cobianchi, Lorenzo; Ćwikła, Jarosław B; Daskalakis, Kosmas; Frilling, Andrea; Garcia-Carbonero, Rocio; ... (2023). Hemicolectomy versus appendectomy for patients with appendiceal neuroendocrine tumours 1-2 cm in size: a retrospective, Europe-wide, pooled cohort study. Lancet oncology, 24(2), pp. 187-194. Elsevier 10.1016/S1470-2045(22)00750-1
Knappskog, Stian; Grob, Tobias; Venizelos, Andreas; Amstutz, Ursula; Hjortland, Geir O; Lothe, Inger M; Kersten, Christian; Hofsli, Eva; Sundlöv, Anna; Elvebakken, Hege; Garresori, Herish; Couvelard, Anne; Svensson, Johanna; Sorbye, Halfdan; Perren, Aurel (2023). Mutation Spectrum in Liquid Versus Solid Biopsies From Patients With Advanced Gastroenteropancreatic Neuroendocrine Carcinoma. JCO precision oncology, 7, e2200336. American Society of Clinical Oncology 10.1200/PO.22.00336
Pavel, Marianne; Bolduan, Felix; Wiedenmann, Bertram; Perren, Aurel (10 November 2022). Current Treatments and Controversies in Neuroendocrine Neoplasia. ASCO Daily News ASCO American Society of Clinical Oncology
Gulde, Sebastian; Foscarini, Alessia; April-Monn, Simon L; Genio, Edoardo; Marangelo, Alessandro; Satam, Swapna; Helbling, Daniel; Falconi, Massimo; Toledo, Rodrigo A; Schrader, Jörg; Perren, Aurel; Marinoni, Ilaria; Pellegata, Natalia S (2022). Combined Targeting of Pathogenetic Mechanisms in Pancreatic Neuroendocrine Tumors Elicits Synergistic Antitumor Effects. Cancers, 14(22) MDPI AG 10.3390/cancers14225481
Depoilly, Thomas; Leroux, Raffaele; Andrade, Dafne; Nicolle, Remy; Dioguardi Burgio, Marco; Marinoni, Ilaria; Dokmak, Safi; Ruszniewski, Philippe; Hentic, Olivia; Paradis, Valérie; De Mestier, Louis; Perren, Aurel; Couvelard, Anne; Cros, Jérôme (2022). Immunophenotypic and molecular characterization of pancreatic neuroendocrine tumors producing serotonin. Modern pathology, 35(11), pp. 1713-1722. Springer Nature 10.1038/s41379-022-01110-x
Janowczyk, Andrew; Baumhoer, Daniel; Dirnhofer, Stefan; Grobholz, Rainer; Kipar, Anja; de Leval, Laurence; Merkler, Doron; Michielin, Olivier; Moch, Holger; Perren, Aurel; Rottenberg, Sven; Rubbia-Brandt, Laura; Rubin, Mark A; Sempoux, Christine; Tolnay, Markus; Zlobec, Inti; Koelzer, Viktor Hendrik (2022). Towards a national strategy for digital pathology in Switzerland. Virchows Archiv, 481(4), pp. 647-652. Springer 10.1007/s00428-022-03345-0
Battistella, Anna; Partelli, Stefano; Andreasi, Valentina; Marinoni, Ilaria; Palumbo, Diego; Tacelli, Matteo; Lena, Marco Schiavo; Muffatti, Francesca; Mushtaq, Junaid; Capurso, Gabriele; Arcidiacono, Paolo Giorgio; De Cobelli, Francesco; Doglioni, Claudio; Perren, Aurel; Falconi, Massimo (2022). Preoperative assessment of microvessel density in nonfunctioning pancreatic neuroendocrine tumors (NF-PanNETs). Surgery, 172(4), pp. 1236-1244. Elsevier 10.1016/j.surg.2022.06.017
Merola, Elettra; Perren, Aurel; Rinke, Anja; Zerbi, Alessandro; McNamara, Mairéad G; Arsenic, Ruza; Fazio, Nicola; de Herder, Wouter; Valle, Juan W; Gress, Thomas M; Wiedenmann, Bertram; Pascher, Andreas; Pavel, Marianne E (2022). High rate of Ki-67 increase in entero-pancreatic NET relapses after surgery with curative intent. Journal of neuroendocrinology, 34(10), e13193. Wiley-Blackwell 10.1111/jne.13193
Pignatti, Emanuele; Altinkiliç, Emre Murat; Bräutigam, Konstantin; Grössl, Michael; Perren, Aurel; Zavolan, Mihaela; Flück, Christa E (2022). Cholesterol deprivation drives DHEA biosynthesis in human adrenals. Endocrinology, 163(7) Endocrine Society 10.1210/endocr/bqac076
Karamitopoulou, Eva; Andreou, Andreas; Wenning, Anna Silvia; Gloor, Beat; Perren, Aurel (2022). High tumor mutational burden (TMB) identifies a microsatellite stable pancreatic cancer subset with prolonged survival and strong anti-tumor immunity. European journal of cancer, 169, pp. 64-73. Elsevier 10.1016/j.ejca.2022.03.033
Simon, Tincy; Riemer, Pamela; Jarosch, Armin; Detjen, Katharina; Di Domenico, Annunziata; Bormann, Felix; Menne, Andrea; Khouja, Slim; Monjé, Nanna; Childs, Liam H; Lenze, Dido; Leser, Ulf; Rossner, Florian; Morkel, Markus; Blüthgen, Nils; Pavel, Marianne; Horst, David; Capper, David; Marinoni, Ilaria; Perren, Aurel; ... (2022). DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas and pancreatic neuroendocrine tumors. Genome medicine, 14(1), p. 24. BioMed Central 10.1186/s13073-022-01018-w
Erickson, Lori A; Mete, Ozgur; Juhlin, C Christofer; Perren, Aurel; Gill, Anthony J (2022). Overview of 2022 WHO Classification of Parathyroid Tumors. Endocrine pathology, 33(1), pp. 64-89. Springer 10.1007/s12022-022-09709-1
van Velthuysen, Marie-Louise F; Couvelard, Anne; Rindi, Guido; Fazio, Nicola; Hörsch, Dieter; Nieveen van Dijkum, Els J; Klöppel, Günter; Perren, Aurel (2022). ENETS standardized (synoptic) reporting for neuroendocrine tumour pathology. Journal of neuroendocrinology, 34(3), e13100. Wiley-Blackwell 10.1111/jne.13100
Nosé, Vania; Gill, Anthony; Teijeiro, José Manuel Cameselle; Perren, Aurel; Erickson, Lori (2022). Overview of the 2022 WHO Classification of Familial Endocrine Tumor Syndromes. Endocrine pathology, 33(1), pp. 197-227. Springer 10.1007/s12022-022-09705-5
Karamitopoulou, Eva; Andreou, Andreas; Pahud de Mortanges, Aurélie; Tinguely, Marianne; Gloor, Beat; Perren, Aurel (2021). PD-1/PD-L1-Associated Immunoarchitectural Patterns Stratify Pancreatic Cancer Patients into Prognostic/Predictive Subgroups. Cancer immunology research, 9(12), pp. 1439-1450. American Association for Cancer Research 10.1158/2326-6066.CIR-21-0144
Venizelos, Andreas; Elvebakken, Hege; Perren, Aurel; Nikolaienko, Oleksii; Deng, Wei; Lothe, Inger Marie B; Couvelard, Anne; Hjortland, Geir Olav; Sundlöv, Anna; Svensson, Johanna; Garresori, Harrish; Kersten, Christian; Hofsli, Eva; Detlefsen, Sönke; Krogh, Merete; Sorbye, Halfdan; Knappskog, Stian (2021). The molecular characteristics of high-grade gastroenteropancreatic neuroendocrine neoplasms. Endocrine-related cancer, 29(1), pp. 1-14. BioScientifica Ltd. 10.1530/ERC-21-0152
April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014
Saghafinia, Sadegh; Homicsko, Krisztian; Di Domenico, Annunziata; Wullschleger, Stephan; Perren, Aurel; Marinoni, Ilaria; Ciriello, Giovanni; Michael, Iacovos P; Hanahan, Douglas (2021). Cancer Cells Retrace a Stepwise Differentiation Program during Malignant Progression. Cancer discovery, 11(10), pp. 2638-2657. American Association for Cancer Research 10.1158/2159-8290.CD-20-1637
Rinke, Anja; Auernhammer, Christoph J; Bodei, Lisa; Kidd, Mark; Krug, Sebastian; Lawlor, Rita; Marinoni, Ilaria; Perren, Aurel; Scarpa, Aldo; Sorbye, Halfdan; Pavel, Marianne Ellen; Weber, Matthias M; Modlin, Irvin; Gress, Thomas M (2021). Treatment of advanced gastroenteropancreatic neuroendocrine neoplasia, are we on the way to personalised medicine? Gut, 70(9), pp. 1768-1781. BMJ Publishing Group 10.1136/gutjnl-2020-321300
Schiavo Lena, Marco; Cangi, Maria Giulia; Pecciarini, Lorenza; Francaviglia, Ilaria; Grassini, Greta; Maire, Renaud; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Doglioni, Claudio (2021). Evidence of a common cell origin in a case of pancreatic mixed intraductal papillary mucinous neoplasm-neuroendocrine tumor. Virchows Archiv, 478(6), pp. 1215-1219. Springer 10.1007/s00428-020-02942-1
Bräutigam, Konstantin; Rodríguez-Calero, Antonio; Kim-Fuchs, Corina; Kollár, Attila; Trepp, Roman; Marinoni, Ilaria; Perren, Aurel (2021). Update on Histological Reporting Changes in Neuroendocrine Neoplasms. Current Oncology Reports, 23(6), p. 65. Springer 10.1007/s11912-021-01062-6
Williams, Michelle D; DeLellis, Ron A; Erickson, Lori A; Gupta, Ruta; Johnson, Sarah J; Kameyama, Kaori; Natu, Sonali; Ng, Tony; Perren, Aurel; Perrier, Nancy D; Seethala, Raja R; Gill, Anthony J (2021). Pathology data set for reporting parathyroid carcinoma and atypical parathyroid neoplasm: recommendations from the International Collaboration on Cancer Reporting. Human pathology, 110, pp. 73-82. Elsevier 10.1016/j.humpath.2020.07.008
April-Monn, Simon Leonhard; Wiedmer, Tabea; Skowronska, Magdalena; Maire, Renaud; Schiavo Lena, Marco; Trippel, Mafalda; Di Domenico, Annunziata; Muffatti, Francesca; Andreasi, Valentina; Capurso, Gabriele; Doglioni, Claudio; Kim-Fuchs, Corina; Gloor, Beat; Zatelli, Maria Chiara; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). 3D Primary Cell Culture: A Novel Preclinical Model For Pancreatic Neuroendocrine Tumors (PanNETs). Neuroendocrinology, 111(3), pp. 273-287. Karger 10.1159/000507669
Niederle, Bruno; Selberherr, Andreas; Bartsch, Detlef; Brandi, Maria Luisa; Doherty, Gerard M; Falconi, Massimo; Goudet, Pierre; Halfdanarson, Thorvardur R; Ito, Tetsuhide; Jensen, Robert T; Larghi, Alberto; Lee, Lingaku; Oberg, Kjell; Pavel, Marianne; Perren, Aurel; Sadowski, Samira M; Tonelli, Francesco; Triponez, Frederic; Valk, Gerlof D; O'Toole, Dermot; ... (2021). Multiple Endocrine Neoplasia Type 1 (MEN1) and the Pancreas - Diagnosis and Treatment of Functioning and Non-Functioning Pancreatic and Duodenal Neuroendocrine Neoplasia within the MEN1 Syndrome - An International Consensus Statement. Neuroendocrinology, 111(7), pp. 609-630. Karger 10.1159/000511791
Young, Reuben S E; Claes, Britt S R; Bowman, Andrew P; Williams, Elizabeth D; Shepherd, Benjamin; Perren, Aurel; Poad, Berwyck L J; Ellis, Shane R; Heeren, Ron M A; Sadowski, Martin C.; Blanksby, Stephen J (2021). Isomer-Resolved Imaging of Prostate Cancer Tissues Reveals Specific Lipid Unsaturation Profiles Associated With Lymphocytes and Abnormal Prostate Epithelia. Frontiers in endocrinology, 12, p. 689600. Frontiers Research Foundation 10.3389/fendo.2021.689600
Storni, Federico; Trepp, Roman; Perren, Aurel; Kollár, Attila; Gloor, Beat; Kim-Fuchs, Corina (2021). [Neuroendocrine tumor of the pancreas: What is new?]. Therapeutische Umschau, 78(10), pp. 615-621. Hogrefe 10.1024/0040-5930/a001318
Di Domenico, Annunziata; Pipinikas, Christodoulos P; Maire, Renaud S; Bräutigam, Konstantin; Simillion, Cedric; Dettmer, Matthias S; Vassella, Erik; Thirlwell, Chrissie; Perren, Aurel; Marinoni, Ilaria (2020). Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression. Communications biology, 3(1), p. 740. Springer Nature 10.1038/s42003-020-01479-y
Prall, Owen W J; Nastevski, Violeta; Xu, Huiling; McEvoy, Christopher R E; Vissers, Joep H A; Byrne, David J; Takano, Elena; Yerneni, Satwica; Ellis, Sarah; Green, Thomas; Mitchell, Catherine A; Murray, William K; Scott, Clare L; Grimmond, Sean M; Hofmann, Oliver; Papenfuss, Anthony; Kee, Damien; Fellowes, Andrew; Brown, Ian S; Miller, Gregory; ... (2020). RAF1 rearrangements are common in pancreatic acinar cell carcinomas. Modern pathology, 33(9), pp. 1811-1821. Nature Publishing Group 10.1038/s41379-020-0545-9
Krug, Sebastian; Weissbach, Julia; Blank, Annika; Perren, Aurel; Haybaeck, Johannes; Fendrich, Volker; Rinke, Anja; Gress, Thomas Mathias; Rosendahl, Jonas; Michl, Patrick (2020). CUX1-Transcriptional Master Regulator of Tumor Progression in Pancreatic Neuroendocrine Tumors. Cancers, 12(7) MDPI AG 10.3390/cancers12071957
Ali, Abir Salwa; Perren, Aurel; Lindskog, Cecilia; Welin, Staffan; Sorbye, Halfdan; Grönberg, Malin; Janson, Eva Tiensuu (2020). Candidate protein biomarkers in pancreatic neuroendocrine neoplasms grade 3. Scientific reports, 10(1), p. 10639. Springer Nature 10.1038/s41598-020-67670-7
Dettmer, Matthias S.; Schmitt, Anja; Komminoth, P; Perren, Aurel (2020). Poorly differentiated thyroid carcinoma : An underdiagnosed entity. Der Pathologe, 41(Suppl 1), pp. 1-8. Springer 10.1007/s00292-019-0600-9
Liu, He; He, Zhaoyue; Germič, Nina; Ademi, Hyrijie; Frangež, Živa; Felser, Andrea; Peng, Shuang; Riether, Carsten; Djonov, Valentin; Nuoffer, Jean-Marc; Bovet, Cédric; Mlinarič-Raščan, Irena; Zlobec, Inti; Fiedler, Georg; Perren, Aurel; Simon, Hans-Uwe (2020). ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell death and differentiation, 27(6), pp. 1965-1980. Springer Nature 10.1038/s41418-019-0476-5
Merola, Elettra; Rinke, Anja; Partelli, Stefano; Gress, Thomas M.; Andreasi, Valentina; Kollár, Attila; Perren, Aurel; Christ, Emanuel; Panzuto, Francesco; Pascher, Andreas; Jann, Henning; Arsenic, Ruza; Cremer, Birgit; Kaemmerer, Daniel; Kump, Patrizia; Lipp, Rainer W.; Agaimy, Abbas; Wiedenmann, Bertram; Falconi, Massimo and Pavel, Marianne E. (2020). Surgery with Radical Intent: Is There an Indication for G3 Neuroendocrine Neoplasms? Annals of surgical oncology, 27(5), pp. 1348-1355. Springer 10.1245/s10434-019-08049-5
Chou, Angela; Brown, Ian S; Kumarasinghe, M Priyanthi; Perren, Aurel; Riley, Denise; Kim, Yoomee; Pajic, Marina; Steinmann, Angela; Rathi, Vivek; Jamieson, Nigel B; Verheij, Joanne; van Roessel, Stijn; Nahm, Chris B; Mittal, Anubhav; Samra, Jaswinder; Gill, Anthony J (2020). RET gene rearrangements occur in a subset of pancreatic acinar cell carcinomas. Modern pathology, 33(4), pp. 657-664. Springer Nature 10.1038/s41379-019-0373-y
Humbert, Magali; Morán, María; de la Cruz-Ojeda, Patricia; Muntané, Jordi; Wiedmer, Tabea; Apostolova, Nadezda; McKenna, Sharon L; Velasco, Guillermo; Balduini, Walter; Eckhart, Leopold; Janji, Bassam; Sampaio-Marques, Belém; Ludovico, Paula; Žerovnik, Eva; Langer, Rupert; Perren, Aurel; Engedal, Nikolai; Tschan, Mario (2020). Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot. Biology, 9(3), pp. 1-24. MDPI 10.3390/biology9030059
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Feller, Anita; Bopp, Matthias; Lorez, Matthias; Zellweger, Ulrich; Adam, Martin; Curjuric, Ivan; Staehelin, Katharina; Perren, Aurel; Bergeron, Yvan; Rapiti, Elisabetta; Mousavi, Mohsen; Diebold, Joachim; Dyntar, Daniela; Bulliard, Jean-Luc; Maspoli Conconi, Manuela; Bordoni, Andrea; Konzelmann, Isabelle; Wagner, Ulrich; Rohrmann, Sabine (2020). Comment on: Wiser et al. Ovarian cancer in Switzerland: incidence and treatment according to hospital registry data. Swiss Med Wkly.2018;148:w14647. Swiss medical weekly, 150(w20179), w20179. EMH Media 10.4414/smw.2020.20179
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Wiesli, Peter; Pavlicek, Vojtech; Brändle, Michael; Pfammatter, Thomas; Perren, Aurel; Schmid, Christoph (2019). Distinct mechanisms of hypoglycaemia in patients with somatostatin-secreting neuroendocrine tumours. Endocrinology, diabetes & metabolism, 2(4), e00083. Wiley 10.1002/edm2.83
Schürch, Christian M; Rölli, Matthias A.; Forster, Stefan; Wasmer, Marie-Hélène; Brühl, Frido; Maire, Renaud S.; Di Pancrazio, Sergio; Ruepp, Marc-David; Giger, Roland; Perren, Aurel; Schmitt, Anja M.; Krebs, Philippe; Charles, Roch-Philippe; Dettmer, Matthias S. (2019). Targeting CD47 in Anaplastic Thyroid Carcinoma Enhances Tumor Phagocytosis by Macrophages and Is a Promising Therapeutic Strategy. Thyroid, 29(7), pp. 979-992. Mary Ann Liebert 10.1089/thy.2018.0555
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Michael, Iacovos P; Saghafinia, Sadegh; Tichet, Mélanie; Zangger, Nadine; Marinoni, Ilaria; Perren, Aurel; Hanahan, Douglas (2019). ALK7 Signaling Manifests a Homeostatic Tissue Barrier That Is Abrogated during Tumorigenesis and Metastasis. Developmental cell, 49(3), 409-424.e6. Cell Press 10.1016/j.devcel.2019.04.015
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Selberherr, Andreas; Koperek, Oskar; Riss, Philipp; Scheuba, Christian; Kaderli, Reto; Perren, Aurel; Niederle, Bruno (2019). Neuroendocrine Liver Metastasis-a Specific Set of Markers to Detect Primary Tumor Sites. Endocrine pathology, 30(1), pp. 31-34. Springer 10.1007/s12022-018-9558-z
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Sorbye, Halfdan; Baudin, Eric; Perren, Aurel (2018). The Problem of High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms: Well-Differentiated Neuroendocrine Tumors, Neuroendocrine Carcinomas, and Beyond. Endocrinology and metabolism clinics of North America, 47(3), pp. 683-698. Elsevier 10.1016/j.ecl.2018.05.001
Henfling, Mieke; Perren, Aurel; Schmitt, Anja Maria; Saddig, Christiane M; Starke, Achim A; Riedl, Robert G; Versleijen-Jonkers, Yvonne M H; Sprij-Mooij, Diane M; Ramaekers, Frans C S; Hofland, Leo; Speel, Ernst-Jan M (2018). The IGF pathway is activated in insulinomas but downregulated in metastatic disease. (In Press). Endocrine-related cancer BioScientifica Ltd. 10.1530/ERC-18-0222
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Evenepoel, Lucie; van Nederveen, Francien H; Oudijk, Lindsey; Papathomas, Thomas G; Restuccia, David F; Belt, Eric J T; de Herder, Wouter W; Feelders, Richard A; Franssen, Gaston J H; Hamoir, Marc; Maiter, Dominique; Perren, Aurel; Timmers, Henri J L M; van Eeden, Susanne; Vroonen, Laurent; Aydin, Selda; Robledo, Mercedes; Vikkula, Miikka; de Krijger, Ronald R; Dinjens, Winand N M; ... (2018). Expression of Contactin 4 is associated with malignant behavior in pheochromocytomas and paragangliomas. The Journal of clinical endocrinology and metabolism, 103(1), pp. 46-55. The Endocrine Society 10.1210/jc.2017-01314
Sadowski, Samira Mercedes; Christ, Emanuel; Bedat, Benoit; Kollár, Attila; Karenovics, Wolfram; Perren, Aurel; Triponez, Frederic (2018). Nationwide multicenter study on the management of pulmonary neuroendocrine (carcinoid) tumors. Endocrine Connections, 7(1), pp. 8-15. BioScientifica 10.1530/EC-17-0271
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Banz Wälti, Yara; Berezowska, Sabina Anna; de Leval, Laurence; Rubbia-Brandt, Laura; Tolnay, Markus; Moch, Holger; Perren, Aurel; Hewer, Ekkehard (2018). Advancing synoptic cancer reports beyond English: the University of Bern/PathoLink approach. Virchows Archiv, 473(5), pp. 655-656. Springer 10.1007/s00428-018-2431-0
Uccella, Silvia; Blank, Annika; Maragliano, Roberta; Sessa, Fausto; Perren, Aurel; La Rosa, Stefano (2017). Calcitonin-Producing Neuroendocrine Neoplasms of the Pancreas: Clinicopathological Study of 25 Cases and Review of the Literature. Endocrine pathology, 28(4), pp. 351-361. Springer 10.1007/s12022-017-9505-4
Wiedmer, Tabea; Blank, Annika; Pantasis, Sophia; Normand, Lea Elena Haaning; Bill, Ruben; Krebs, Philippe; Tschan, Mario; Marinoni, Ilaria; Perren, Aurel (2017). Autophagy inhibition improves sunitinib efficacy in pancreatic neuroendocrine tumors via a lysosome-dependent mechanism. Molecular cancer therapeutics, 16(11), pp. 2502-2515. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-17-0136
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Klöppel, Günter; Klimstra, David S; Hruban, Ralph H; Adsay, Volkan; Capella, Carlo; Couvelard, Anne; Komminoth, Paul; La Rosa, Stefano; Ohike, Nobuyuki; Osamura, Robert Y; Perren, Aurel; Scoazec, Jean-Yves; Rindi, Guido (2017). Pancreatic neuroendocrine tumors: update on the new World Health Organization classification. AJSP: Reviews & Reports, 22(5), pp. 233-239. 10.1097/PCR.0000000000000211
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Galleberg, R B; Knigge, U; Tiensuu Janson, E; Vestermark, L W; Haugvik, S-P; Ladekarl, M; Langer, S W; Grønbæk, H; Österlund, P; Hjortland, G O; Assmus, J; Tang, L; Perren, Aurel; Sorbye, H (2017). Results after surgical treatment of liver metastases in patients with high-grade gastroenteropancreatic neuroendocrine carcinomas. European journal of surgical oncology EJSO, 43(9), pp. 1682-1689. Elsevier 10.1016/j.ejso.2017.04.010
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Marti, Nesa Magdalena; Galván, José A.; Pandey, Amit Vikram; Trippel, Mafalda; Tapia, Coya; Müller, Michel; Perren, Aurel; Flück Pandey, Christa Emma (2017). Genes and proteins of the alternative steroid backdoor pathway for dihydrotestosterone synthesis are expressed in the human ovary and seem enhanced in the polycystic ovary syndrome. Molecular and cellular endocrinology, 441, pp. 116-123. Elsevier Ireland 10.1016/j.mce.2016.07.029
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Marinoni, Ilaria; Wiederkehr, Astrid; Wiedmer, Tabea; Pantasis, Sophia; Di Domenico, Annunziata; Rasmus Möller, Frank; Vassella, Erik; Schmitt Kurrer, Anja; Perren, Aurel (2017). Hypo-methylation mediates chromosomal instability in pancreatic NET. Endocrine-related cancer, 24(3), pp. 137-146. BioScientifica Ltd. 10.1530/ERC-16-0554
Banz Wälti, Yara; Tzankov, Alexandar; Dirnhofer, Stephan; Perren, Aurel; Hoeller, Sylvia (2017). Lymphadenectomy Specimens in a Large Retrospective Cohort of Pediatric Patients Reveal No in situ Lymphomas but a Broad Spectrum of Reactive Changes. Pathobiology, 84(3), pp. 139-143. Karger 10.1159/000449253
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Couvelard, A.; Hammel, P.; Komminoth, P; Mete, O; Pacak, K; Perren, Aurel; Stratakis, C (2017). Familial Tumor Syndromes: Von Hippel-Lindau syndrome. In: Lloyd, Ricardo V.; Osamura, Robert Y.; Klöppel, Günter; Rosai, Juan (eds.) WHO classification of tumours of endocrine organs. WHO/IARC classification of tumours: Vol. 10. Lyon: IARC
Taelman, Vincent; Radojewski, Piotr; Marincek, Nicolas; Ben-Shlomo, Anat; Grotzky, Andrea; Olariu, Cristina I; Perren, Aurel; Stettler, Christoph; Krause, Thomas Michael; Meier, Lorenz; Cescato, Renzo; Walter, Martin A. (2016). Upregulation of Key Molecules for Targeted Imaging and Therapy. Journal of nuclear medicine, 57(11), pp. 1805-1810. Society of Nuclear Medicine 10.2967/jnumed.115.165092
Falletta, Simona; Partelli, Stefano; Rubini, Corrado; Nann, Dominik; Doria, Andrea; Marinoni, Ilaria; Polenta, Vanessa; Di Pasquale, Carmelina; Degli Uberti, Ettore; Perren, Aurel; Falconi, Massimo; Zatelli, Maria Chiara (2016). mTOR inhibitors response and mTOR pathway in pancreatic neuroendocrine tumors. Endocrine-related cancer, 23(11), pp. 883-891. BioScientifica Ltd. 10.1530/ERC-16-0329
Wartenberg, Martin; Centeno, Irene; Haemmig, Stefan; Vassella, Erik; Zlobec, Inti; Galván, José A.; Neuenschwander, Maja; Schlup, Cornelia; Gloor, Beat; Lugli, Alessandro; Perren, Aurel; Karamitopoulou, Evanthia (2016). PTEN alterations of the stromal cells characterise an aggressive subpopulation of pancreatic cancer with enhanced metastatic potential. European journal of cancer, 65, pp. 80-90. Elsevier 10.1016/j.ejca.2016.06.013
Schmitt Kurrer, Anja; Marinoni, Ilaria; Blank, Annika; Perren, Aurel (2016). New Genetics and Genomic Data on Pancreatic Neuroendocrine Tumors: Implications for Diagnosis, Treatment, and Targeted Therapies. Endocrine pathology, 27(3), pp. 200-204. Springer 10.1007/s12022-016-9447-2
Schwetz, Verena; Horvath, Karl; Kump, Patrizia; Lackner, Carolin; Perren, Aurel; Forrer, Flavio; Pieber, Thomas R; Treiber, Gerlies; Sourij, Harald; Mader, Julia K (2016). Successful Medical Treatment of Adult Nesidioblastosis With Pasireotide over 3 Years: A Case Report. Medicine, 95(14), e3272. Lippincott Williams & Wilkins 10.1097/MD.0000000000003272
Pape, U.-F.; Niederle, B.; Costa, F.; Gross, D.; Kelestimur, F.; Kianmanesh, R.; Knigge, U.; Öberg, K.; Pavel, M.; Perren, Aurel; Toumpanakis, C.; O'Connor, J.; Krenning, E.; Reed, N.; O'Toole, D. (2016). ENETS Consensus Guidelines for Neuroendocrine Neoplasms of the Appendix (Excluding Goblet Cell Carcinomas). Neuroendocrinology, 103(2), pp. 144-152. Karger 10.1159/000443165
Schmitt Kurrer, Anja; Blank, Annika; Marinoni, Ilaria; Komminoth, Paul; Perren, Aurel (2016). Histopathology of NET: Current concepts and new developments. Best practice & research. Clinical endocrinology & metabolism, 30(1), pp. 33-43. Elsevier 10.1016/j.beem.2016.02.002
Niederle, B.; Pape, U.-F.; Costa, F.; Gross, D.; Kelestimur, F.; Knigge, U.; Öberg, K.; Pavel, M.; Perren, Aurel; Toumpanakis, C.; O'Connor, J.; O'Toole, D.; Krenning, E.; Reed, N.; Kianmanesh, R. (2016). ENETS Consensus Guidelines Update for Neuroendocrine Neoplasms of the Jejunum and Ileum. Neuroendocrinology, 103(2), pp. 125-138. Karger 10.1159/000443170
Kollár, Attila; Blank, Annika; Perren, Aurel; Bütikofer, Lukas; Stettler, Christoph; Christ, Emanuel (2016). Additional malignancies in patients with neuroendocrine tumours: analysis of the SwissNET registry. Swiss medical weekly, 146, w14362. EMH Schweizerischer Ärzteverlag 10.4414/smw.2016.14362
Brügger, Fabienne; Dettmer, Matthias; Neuenschwander, Maja; Perren, Aurel; Marinoni, Ilaria; Hewer, Ekkehard (2016). TERT Promoter Mutations but not the Alternative Lengthening of Telomeres Phenotype Are Present in a Subset of Ependymomas and Are Associated With Adult Onset and Progression to Ependymosarcoma. Journal of neuropathology and experimental neurology, 76(1), pp. 61-66. Oxford University Press 10.1093/jnen/nlw106
Blank, Annika; Wehweck, Laura; Marinoni, Ilaria; Boos, Laura Amanda Meret Sophie; Bergmann, Frank; Schmitt Kurrer, Anja; Perren, Aurel (2015). Interlaboratory variability of MIB1 staining in well-differentiated pancreatic neuroendocrine tumors. Virchows Archiv, 467(5), pp. 543-550. Springer 10.1007/s00428-015-1843-3
Galli, Serena; Zlobec, Inti; Schürch, Christian; Perren, Aurel; Ochsenbein, Adrian; Banz Wälti, Yara (2015). CD47 protein expression in acute myeloid leukemia: A tissue microarray-based analysis. Leukemia research, 39(7), pp. 749-756. Elsevier 10.1016/j.leukres.2015.04.007
Galván Hernández, José Alberto; Zlobec, Inti; Wartenberg, Martin; Lugli, Alessandro; Gloor, Beat; Perren, Aurel; Karamitopoulou, Evanthia (2015). Expression of E-cadherin repressors SNAIL, ZEB1 and ZEB2 by tumour and stromal cells influences tumour-budding phenotype and suggests heterogeneity of stromal cells in pancreatic cancer. British journal of cancer, 112(12), pp. 1944-1950. Nature Publishing Group 10.1038/bjc.2015.177
Dettmer, Matthias; Schmitt Kurrer, Anja; Steinert, Hans; Capper, David; Moch, Holger; Komminoth, Paul; Perren, Aurel (2015). Tall cell papillary thyroid carcinoma: new diagnostic criteria and mutations in BRAF and TERT. Endocrine-related cancer, 22(3), pp. 419-429. BioScientifica Ltd. 10.1530/ERC-15-0057
Christ, Emanuel; Wild, Damian; Antwi, Kwadwo; Waser, Beatrice; Fani, Melpomeni; Schwanda, Stefanie; Heye, Tobias; Schmid, Christoph; Baer, Hans Ulrich; Perren, Aurel; Reubi, Jean Claude (2015). Preoperative localization of adult nesidioblastosis using (68)Ga-DOTA-exendin-4-PET/CT. Endocrine, 50(3), pp. 821-823. Springer 10.1007/s12020-015-0633-7
Komminoth, P; Perren, Aurel (2015). What is new in the pathology of pancreatic neuroendocrine tumors? Pathologe, 36(3), pp. 220-228. Springer-Medizin-Verlag 10.1007/s00292-015-0023-1
Wartenberg, Martin; Zlobec, Inti; Perren, Aurel; Kölzer, Viktor; Gloor, Beat; Lugli, Alessandro; Karamitopoulou, Evanthia (2015). Accumulation of FOXP3+T-cells in the tumor microenvironment is associated with an epithelial-mesenchymal-transition-type tumor budding phenotype and is an independent prognostic factor in surgically resected pancreatic ductal adenocarcinoma. OncoTarget, 6(6), pp. 4190-4201. Impact Journals LLC
Alkatout, Ibrahim; Friemel, Juliane; Sitek, Barbara; Anlauf, Martin; Eisenach, Patricia A; Stühler, Kai; Scarpa, Aldo; Perren, Aurel; Meyer, Helmut E; Knoefel, Wolfram T; Klöppel, Günter; Sipos, Bence (2015). Novel prognostic markers revealed by a proteomic approach separating benign from malignant insulinomas. Modern pathology, 28(1), pp. 69-79. Nature Publishing Group 10.1038/modpathol.2014.82
Caplin, M E; Baudin, E; Ferolla, P; Filosso, P; Garcia-Yuste, M; Lim, E; Oberg, K; Pelosi, G; Perren, Aurel; Rossi, R E; Travis, W D (2015). Pulmonary neuroendocrine (carcinoid) tumors: European Neuroendocrine Tumor Society expert consensus and recommendations for best practice for typical and atypical pulmonary carcinoids. Annals of oncology, 26(8), pp. 1604-1620. Oxford University Press 10.1093/annonc/mdv041
Blank, Annika; Schmitt, Anja; Perren, Aurel (2015). Pathology: Classification and Immunoprofile. Frontiers of hormone research, 44, pp. 104-114. Basel: Karger 10.1159/000382135
Gündisch, Sibylle; Slotta-Huspenina, Julia; Verderio, Paolo; Ciniselli, Chiara Maura; Pizzamiglio, Sara; Schott, Christina; Drecoll, Enken; Viertler, Christian; Zatloukal, Kurt; Kap, Marcel; Riegman, Peter; Esposito, Irene; Specht, Katja; Babaryka, Gregor; Asslaber, Martin; Bodó, Koppany; den Bakker, Michael; den Hollander, Jan; Fend, Falko; Neumann, Jens; ... (2014). Evaluation of colon cancer histomorphology: a comparison between formalin and PAXgene tissue fixation by an international ring trial. Virchows Archiv, 465(5), pp. 509-519. Springer 10.1007/s00428-014-1624-4
Waser, Beatrice; Blank, Annika; Karamitopoulou, Evanthia; Perren, Aurel; Reubi, Jean-Claude (2014). Glucagon-like-peptide-1 receptor expression in normal and diseased human thyroid and pancreas. Modern pathology, 28(3), pp. 391-402. Nature Publishing Group 10.1038/modpathol.2014.113
Klöppel, Günter; Anlauf, Martin; Perren, Aurel; Sipos, Bence (2014). Hyperplasia to neoplasia sequence of duodenal and pancreatic neuroendocrine diseases and pseudohyperplasia of the PP-cells in the pancreas. Endocrine pathology, 25(2), pp. 181-185. Springer 10.1007/s12022-014-9317-8
Anlauf, M; Sipos, B; Boeck, I; Baldus, S E; Heikaus, S; Krausch, M; Knoefel, W T; Begum, N; Goretzki, P; Schott, M; Auernhammer, C J; Cremer, B; Rinke, A; Ezziddin, S; Fottner, C; Pöpperl, G; Lahner, H; Hörsch, D; Gabbert, H E; Komminoth, P; ... (2014). [Neuroendocrine neoplasms of the distal jejunum and ileum]. Pathologe, 35(3), pp. 283-293. Springer-Medizin-Verlag 10.1007/s00292-013-1888-5
Dettmer, Matthias; Perren, Aurel; Moch, Holger; Komminoth, Paul; Nikiforov, Yuri E; Nikiforova, Marina N (2014). MicroRNA profile of poorly differentiated thyroid carcinomas: new diagnostic and prognostic insights. Journal of molecular endocrinology, 52(2), pp. 181-189. Journal of Endocrinology 10.1530/JME-13-0266
Fleischmann, Achim; Thalmann, George; Perren, Aurel; Seiler, Roland (2014). Tumor regression grade of urothelial bladder cancer after neoadjuvant chemotherapy: a novel and successful strategy to predict survival. The American journal of surgical pathology, 38(3), pp. 325-332. Lippincott Williams & Wilkins 10.1097/PAS.0000000000000142
Frei, Marc; Buettner, Michael; Perren, Aurel; Reichart, Peter; Bornstein, Michael M. (2014). Diagnosis and interdisciplinary treatment of a botryoid odontogenic cyst in the posterior mandible: report of a case. Quintessence international, 45(3), pp. 233-237. Quintessenz Verlags-GmbH 10.3290/j.qi.a31211
Swarts, Dorian R. A.; Scarpa, Aldo; Corbo, Vincenzo; Van Criekinge, Wim; van Engeland, Manon; Gatti, Gaia; Henfling, Mieke E. R.; Papotti, Mauro; Perren, Aurel; Ramaekers, Frans C. S.; Speel, Ernst-Jan M.; Volante, Marco (2014). MEN1 Gene Mutation and Reduced Expression Are Associated With Poor Prognosis in Pulmonary Carcinoids. Journal of clinical endocrinology and metabolism, 99(2), E374-E378. Endocrine Society 10.1210/jc.2013-2782
Marinoni, Ilaria; Schmitt Kurrer, Anja; Vassella, Erik; Dettmer, Matthias; Rudolph, Thomas; Banz, Vanessa Martine; Hunger, Fabio; Pasquinelli, Silvan; Speel, Ernst-Jan; Perren, Aurel (2014). Loss of DAXX and ATRX are associated with chromosome instability and reduced survival of patients with pancreatic neuroendocrine tumors. Gastroenterology, 146(2), 453-460.e5. Elsevier 10.1053/j.gastro.2013.10.020
Schlitter, Anna Melissa; Born, Diana; Bettstetter, Marcus; Specht, Katja; Kim-Fuchs, Corina; Riener, Marc-Oliver; Jeliazkova, Petia; Sipos, Bence; Siveke, Jens T.; Terris, Benoit; Zen, Yoh; Schuster, Tibor; Höfler, Heinz; Perren, Aurel; Klöppel, Günter; Esposito, Irene (2014). Intraductal papillary neoplasms of the bile duct: stepwise progression to carcinoma involves common molecular pathways. Modern pathology, 27(1), pp. 73-86. Nature Publishing Group 10.1038/modpathol.2013.112
Seiler, Roland; Thalmann, George N.; Rotzer, Diana; Perren, Aurel; Fleischmann, Achim (2014). CCND1/CyclinD1 status in metastasizing bladder cancer: a prognosticator and predictor of chemotherapeutic response. Modern pathology, 27(1), pp. 87-95. Nature Publishing Group 10.1038/modpathol.2013.125
Zlobec, Inti; Suter, Guido; Perren, Aurel; Lugli, Alessandro (2014). A next-generation tissue microarray (ngTMA) protocol for biomarker studies. Journal of visualized experiments(91), p. 51893. MYJoVE Corporation 10.3791/51893
Schmitt Kurrer, Anja; Pavel, Marianne; Rudolph, Thomas; Dawson, Heather; Blank, Annika; Komminoth, Paul; Vassella, Erik; Perren, Aurel (2014). Prognostic and predictive roles of MGMT protein expression and promoter methylation in sporadic pancreatic neuroendocrine neoplasms. Neuroendocrinology, 100(1), pp. 35-44. Karger 10.1159/000365514
Warth, Rainer; Perren, Aurel (2014). Construction of a Business Model to Assure Financial Sustainability of Biobanks. Biopreservation and biobanking, 12(6), pp. 389-394. Liebert 10.1089/bio.2014.0057
Dettmer, Matthias; Perren, Aurel; Moch, Holger; Komminoth, Paul; Nikiforov, Yuri E.; Nikiforova, Marina N. (2013). Comprehensive MicroRNA expression profiling identifies novel markers in follicular variant of papillary thyroid carcinoma. Thyroid, 23(11), pp. 1383-1389. Mary Ann Liebert 10.1089/thy.2012.0632
Christ, Emanuel; Wild, Damian; Ederer, Susanne; Béhé, Martin; Nicolas, Guillaume; Caplin, Martyn E.; Brändle, Michael; Clerici, Thomas; Fischli, Stefan; Stettler, Christoph; Ell, Peter J.; Seufert, Jochen; Gloor, Beat; Perren, Aurel; Reubi, Jean-Claude; Forrer, Flavio (2013). Glucagon-like peptide-1 receptor imaging for the localisation of insulinomas: a prospective multicentre imaging study. The lancet. Diabetes & endocrinology, 1(2), pp. 115-122. Elsevier 10.1016/S2213-8587(13)70049-4
Boos, Laura; Dettmer, Matthias; Schmitt Kurrer, Anja; Rudolph, Thomas; Steinert, Hans; Moch, Holger; Sobrinho-Simões, Manuel; Komminoth, Paul; Perren, Aurel (2013). Diagnostic and prognostic implications of the PAX8-PPARγ translocation in thyroid carcinomas-a TMA-based study of 226 cases. Histopathology, 63(2), pp. 234-241. Blackwell Scientific Publications 10.1111/his.12150
Agaimy, Abbas; Erlenbach-Wünsch, Katharina; Konukiewitz, Björn; Schmitt Kurrer, Anja; Rieker, Ralf J.; Vieth, Michael; Kiesewetter, Franklin; Hartmann, Arndt; Zamboni, Giuseppe; Perren, Aurel; Klöppel, Günter (2013). ISL1 expression is not restricted to pancreatic well-differentiated neuroendocrine neoplasms, but is also commonly found in well and poorly differentiated neuroendocrine neoplasms of extrapancreatic origin. Modern pathology, 26(7), pp. 995-1003. Nature Publishing Group 10.1038/modpathol.2013.40
Zlobec, Inti; Kölzer, Viktor; Dawson, Heather; Perren, Aurel; Lugli, Alessandro (2013). Next-generation tissue microarray (ngTMA) increases the quality of biomarker studies: an example using CD3, CD8, and CD45RO in the tumor microenvironment of six different solid tumor types. Journal of translational medicine, 11(1), p. 104. BioMed Central 10.1186/1479-5876-11-104
Reber, Rebekka; Banz Wälti, Yara; Garamvölgyi, Esther; Perren, Aurel; Novak, Urban (2013). Determination of the molecular subtypes of diffuse large B-cell lymphomas using immunohistochemistry: a case series from the Inselspital, Bern, and a critical appraisal of this determination in Switzerland. Swiss medical weekly, 143, w13748. EMH Schweizerischer Ärzteverlag 10.4414/smw.2013.13748
Dettmer, Matthias; Vogetseder, Alexander; Durso, Mary Beth; Moch, Holger; Komminoth, Paul; Perren, Aurel; Nikiforov, Yuri E; Nikiforova, Marina N (2013). MicroRNA Expression Array Identifies Novel Diagnostic Markers for Conventional and Oncocytic Follicular Thyroid Carcinomas. Journal of clinical endocrinology and metabolism, 98(1), E1-7. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2012-2694
He, Zhaoyue; Liu, He; Agostini, M.; Yousefi, Shida; Perren, Aurel; Tschan, Mario; Mak, TW; Melino, G:; Simon, Hans-Uwe (2013). p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene. Cell death and differentiation, 20(10), pp. 1415-1424. Nature Publishing Group 10.1038/cdd.2013.104
Maskey, Dipak; Yousefi, Shida; Schmid, Ines; Zlobec, Inti; Perren, Aurel; Friis, Robert; Simon, Hans-Uwe (2013). ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy. Nature communications, 4(1), p. 2130. Nature Publishing Group 10.1038/ncomms3130
Al-Chalabi, Ahmed; Matevossian, Edouard; v. Thaden, Anne-K.; Luppa, Peter; Neiss, Albrecht; Schuster, Tibor; Yang, Zejian; Schreiber, Catherine; Schimmel, Patrick; Nairz, Ewald; Radermacher, Peter; Huber, Wolfgang; Schmid, Roland M.; Kreymann, Bernhard; Perren, Aurel (2013). Evaluation of the Hepa Wash® treatment in pigs with acute liver failure. BMC gastroenterology, 13, p. 83. BioMed Central 10.1186/1471-230X-13-83
Karamitopoulou, Evanthia; Zlobec, Inti; Gloor, Beat; Kondi-Pafiti, Agathi; Lugli, Alessandro; Perren, Aurel (2013). Loss of Raf-1 kinase inhibitor protein (RKIP) is strongly associated with high-grade tumor budding and correlates with an aggressive phenotype in pancreatic ductal adenocarcinoma (PDAC). Journal of translational medicine, 11, p. 311. BioMed Central 10.1186/1479-5876-11-311
Karamitopoulou, Evanthia; Zlobec, Inti; Perren, Aurel; Gloor, Beat; Lugli, Alessandro (2013). Increased tumor-budding/CD8+lymphocytes ratio is associated with metastasis and venous invasion in Pancreatic Ductal Adenocarcinoma (PDAC). Virchows Archiv, 463(2), p. 106. Springer
Zlobec, Inti; Kölzer, Viktor; Dawson, Heather; Perren, Aurel; Lugli, Alessandro (2013). Next-generation tissue microarray (ngTMA) strengthens pathology biomarker research: An exemplary study of the tumor microenvironment using CD3, CD8, and CD45RO in six different solid tumor types. Virchows Archiv, 463(2), p. 108. Springer
Karamitopoulou, Evanthia; Zlobec, Inti; Gloor, Beat; Lugli, Alessandro; Perren, Aurel (2013). PTEN Loss in the Neoplastic Stroma of Pancreatic Ductal Adenocarcinoma (PDAC) Is a Strong Predictor of Distant Metastasis. Gastroenterology, 144(5) Elsevier
Karamitopoulou, Evanthia; Zlobec, Inti; Gloor, Beat; Kondi-Pafiti, A.; Lugli, Alessandro; Perren, Aurel (2013). Loss of Raf-1 Kinase Inhibitor Protein (RKIP) promotes Epithelial Mesenchymal Transition (EMT) and correlates with aggressive phenotype in Pancreatic Ductal Adenocarcinoma (PDAC). Virchows Archiv, 463(2), p. 139. Springer
Gimm, Oliver; DeMicco, Catherine; Perren, Aurel; Giammarile, Francesco; Walz, Martin K; Brunaud, Laurent (2012). Malignant pheochromocytomas and paragangliomas: a diagnostic challenge. Langenbeck's archives of surgery, 397(2), pp. 155-77. Berlin: Springer 10.1007/s00423-011-0880-x
Seleznik, Gitta M; Reding, Theresia; Romrig, Franziska; Saito, Yasuyuki; Mildner, Alexander; Segerer, Stephan; Sun, Li-Kang; Regenass, Stephan; Lech, Maciej; Anders, Hans-Joachim; McHugh, Donal; Kumagi, Teru; Hiasa, Yoichi; Lackner, Carolin; Haybaeck, Johannes; Angst, Eliane; Perren, Aurel; Balmer, Maria Luisa; Slack, Emma; MacPherson, Andrew; ... (2012). Lymphotoxin β receptor signaling promotes development of autoimmune pancreatitis. Gastroenterology, 143(5), pp. 1361-74. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2012.07.112
Marinoni, Ilaria; Lee, Misu; Mountford, Steffeni; Perren, Aurel; Bravi, Ilaria; Jennen, Louise; Feuchtinger, Annette; Drouin, Jacques; Roncaroli, Federico; Pellegata, Natalia S (2012). Characterization of MENX-associated pituitary tumours. Neuropathology & applied neurobiology, 39(3), pp. 256-269. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2990.2012.01278.x
Dettmer, Matthias; Schmitt, Anja; Steinert, Hans; Moch, Holger; Komminoth, Paul; Perren, Aurel (2012). Poorly differentiated oncocytic thyroid carcinoma--diagnostic implications and outcome. Histopathology, 60(7), pp. 1045-51. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2559.2012.04188.x
Pape, Ulrich-Frank; Perren, Aurel; Niederle, Bruno; Gross, David; Gress, Thomas; Costa, Frederico; Arnold, Rudolf; Denecke, Timm; Plöckinger, Ursula; Salazar, Ramon; Grossman, Ashley (2012). ENETS Consensus Guidelines for the management of patients with neuroendocrine neoplasms from the jejuno-ileum and the appendix including goblet cell carcinomas. Neuroendocrinology, 95(2), pp. 135-56. Basel: Karger 10.1159/000335629
Körner, Meike; Waser, Beatrice; Schonbrunn, Agnes; Perren, Aurel; Reubi, Jean (2012). Somatostatin receptor subtype 2A immunohistochemistry using a new monoclonal antibody selects tumors suitable for in vivo somatostatin receptor targeting. The American journal of surgical pathology, 36(2), pp. 242-52. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/PAS.0b013e31823d07f3
Wild, Damian; Christ, Emanuel; Caplin, Martyn E; Kurzawinski, Tom R; Forrer, Flavio; Brändle, Michael; Seufert, Jochen; Weber, Wolfgang A; Bomanji, Jamshed; Perren, Aurel; Ell, Peter J; Reubi, Jean Claude (2011). Glucagon-like peptide-1 versus somatostatin receptor targeting reveals 2 distinct forms of malignant insulinomas. Journal of nuclear medicine, 52(7), pp. 1073-8. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.110.085142
Hagemann, Kerstin; Zanolari Calderari, Maura; Perren, Aurel; Cree, Ian; Mullis, Primus E; Flück, Christa E (2011). Atypical presentation of a hormonally active adrenocortical tumor in an adolescent leading to delayed diagnosis. Hormones - international journal of endocrinology and metabolism, 10(4), pp. 317-25. Athens: Hellenic Endocrine Soc.
Dettmer, Matthias; Schmitt, Anja; Steinert, Hans; Haldemann, Andreas; Meili, Andreas; Moch, Holger; Komminoth, Paul; Perren, Aurel (2011). Poorly differentiated thyroid carcinomas: how much poorly differentiated is needed? The American journal of surgical pathology, 35(12), pp. 1866-72. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/PAS.0b013e31822cf962
Simeon-Dubach, Daniel; Perren, Aurel (2011). Better provenance for biobank samples. Nature, 475(7357), pp. 454-5. London: Macmillan Journals Ltd. 10.1038/475454d
Swarts, Dorian R A; Claessen, Sandra M H; Jonkers, Yvonne M H; van Suylen, Robert-Jan; Dingemans, Anne-Marie C; de Herder, Wouter W; de Krijger, Ronald R; Smit, Egbert F; Thunnissen, Frederik B J M; Seldenrijk, Cornelis A; Vink, Aryan; Perren, Aurel; Ramaekers, Frans C S; Speel, Ernst-Jan M (2011). Deletions of 11q22.3-q25 are associated with atypical lung carcinoids and poor clinical outcome. American journal of pathology, 179(3), pp. 1129-37. New York, N.Y.: Elsevier 10.1016/j.ajpath.2011.05.028
Miederer, Matthias; Molatore, Sara; Marinoni, Ilaria; Perren, Aurel; Spitzweg, Christine; Reder, Sybille; Wester, Hans-Jürgen; Buck, Andreas K; Schwaiger, Markus; Pellegata, Natalia S (2011). Functional Imaging of Pheochromocytoma with Ga-DOTATOC and C-HED in a Genetically Defined Rat Model of Multiple Endocrine Neoplasia. International journal of molecular imaging, 2011, p. 175352. New York, N.Y.: Hindawi 10.1155/2011/175352
Hermann, Gratiana; Konukiewitz, Björn; Schmitt, Anja; Perren, Aurel; Klöppel, Günter (2011). Hormonally defined pancreatic and duodenal neuroendocrine tumors differ in their transcription factor signatures: expression of ISL1, PDX1, NGN3, and CDX2. Virchows Archiv, 459(2), pp. 147-54. Berlin: Springer 10.1007/s00428-011-1118-6
Wiesli, Peter; Uthoff, Heiko; Perren, Aurel; Pfammatter, Thomas; Zwimpfer, Cornelia; Seiler, Heidi; Kindhauser, René; Spinas, Giatgen A; Schmid, Christoph (2011). Are biochemical markers of neuroendocrine tumors coreleased with insulin following local calcium stimulation in patients with insulinomas? Pancreas, 40(7), pp. 995-9. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/MPA.0b013e31821ffce1
La Rosa, Stefano; Franzi, Francesca; Albarello, Luca; Schmitt, Anja; Bernasconi, Barbara; Tibiletti, Maria Grazia; Finzi, Giovanna; Placidi, Claudia; Perren, Aurel; Capella, Carlo (2011). Serotonin-producing enterochromaffin cell tumors of the pancreas: clinicopathologic study of 15 cases and comparison with intestinal enterochromaffin cell tumors. Pancreas, 40(6), pp. 883-95. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/MPA.0b013e31822041a9
Burgermeister, Elke; Friedrich, Teresa; Hitkova, Ivana; Regel, Ivonne; Einwächter, Henrik; Zimmermann, Wolfgang; Röcken, Christoph; Perren, Aurel; Wright, Matthew B; Schmid, Roland M; Seger, Rony; Ebert, Matthias P A (2011). The Ras inhibitors caveolin-1 and docking protein 1 activate peroxisome proliferator-activated receptor ? through spatial relocalization at helix 7 of its ligand-binding domain. Molecular and cellular biology, 31(16), pp. 3497-510. Washington, D.C.: American Society for Microbiology 10.1128/MCB.01421-10
Künzli, Beat M; Bernlochner, Maria-Isabell; Rath, Stephan; Käser, Samuel; Csizmadia, Eva; Enjyoji, Keiichi; Cowan, Peter; d'Apice, Anthony; Dwyer, Karen; Rosenberg, Robert; Perren, Aurel; Friess, Helmut; Maurer, Christoph A; Robson, Simon C (2011). Impact of CD39 and purinergic signalling on the growth and metastasis of colorectal cancer. Purinergic signalling, 7(2), pp. 231-41. Dordrecht: Springer 10.1007/s11302-011-9228-9
Spizzo, Gilbert; Bernardini, Karin; Pieramico, Oreste; Buratti, Thomas; Platzgummer, Stefan; Farsad, Mohsen; Schmitt, Anja M; Perren, Aurel; Vogelsang, Holger; Promegger, Rupert; Bale, Reto; Gabriel, Michael; Nevinny, Meinhard; Gastl, Guenther; Mitterer, Manfred (2011). Clinical aspects, diagnostic challenges and management of patients with neuroendocrine tumors (NETs). Onkologie, 34(3), pp. 139-46. Basel: Karger 10.1159/000324778
von Wolff, Michael; Kollmann, Zahraa; Perren, Aurel; Banz, Yara (2011). Secondary amenorrhea by androgen-producing oncocytic adrenocortical adenoma. Gynäkologische Endokrinologie, 9(3), pp. 200-201. Springer-Medizin-Verlag 10.1007/s10304-011-0422-1
Molatore, Sara; Liyanarachchi, Sandya; Irmler, Martin; Perren, Aurel; Mannelli, Massimo; Ercolino, Tonino; Beuschlein, Felix; Jarzab, Barbara; Wloch, Jan; Ziaja, Jacek; Zoubaa, Saida; Neff, Frauke; Beckers, Johannes; Höfler, Heinz; Atkinson, Michael J; Pellegata, Natalia S (2010). Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 107(43), pp. 18493-8. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.1003956107
Mueller-Garamvölgyi, Esther; Perren, Aurel; Schmitt, Anja (2010). [Pathology of malignant lymphomas--clarity instead of confusion]. Therapeutische Umschau, 67(10), pp. 497-500. Bern: Huber
Blank, Annika; Schmitt, Anja M; Korpershoek, Esther; van Nederveen, Francien; Rudolph, Thomas; Weber, Nicole; Strebel, Räto Thomas; de Krijger, Ronald; Komminoth, Paul; Perren, Aurel (2010). SDHB loss predicts malignancy in pheochromocytomas/sympathethic paragangliomas, but not through hypoxia signalling. Endocrine-related cancer, 17(4), pp. 919-28. Bristol: BioScientifica Ltd. 10.1677/ERC-09-0316
Bonin, Serena; Hlubek, Falk; Benhattar, Jean; Denkert, Carsten; Dietel, Manfred; Fernandez, Pedro L; Höfler, Gerald; Kothmaier, Hannelore; Kruslin, Bozo; Mazzanti, Chiara Maria; Perren, Aurel; Popper, Helmuth; Scarpa, Aldo; Soares, Paula; Stanta, Giorgio; Groenen, Patricia J T A (2010). Multicentre validation study of nucleic acids extraction from FFPE tissues. Virchows Archiv, 457(3), pp. 309-17. Berlin: Springer 10.1007/s00428-010-0917-5
Pavel, Marianne; Grossman, Ashley; Arnold, Rudolf; Perren, Aurel; Kaltsas, Gregory; Steinmüller, Thomas; de Herder, Wouter; Nikou, George; Plöckinger, Ursula; Lopes, Jose Manuel; Sasano, Hironobu; Buscombe, John; Lind, Peter; O'Toole, Dermot; Oberg, Kjell (2010). ENETS consensus guidelines for the management of brain, cardiac and ovarian metastases from neuroendocrine tumors. Neuroendocrinology, 91(4), pp. 326-32. Basel: Karger 10.1159/000287277
Montani, Matteo; Heinimann, Karl; von Teichman, Adriana; Rudolph, Thomas; Perren, Aurel; Moch, Holger (2010). VHL-gene deletion in single renal tubular epithelial cells and renal tubular cysts: further evidence for a cyst-dependent progression pathway of clear cell renal carcinoma in von Hippel-Lindau disease. The American journal of surgical pathology, 34(6), pp. 806-15. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/PAS.0b013e3181ddf54d
Klöppel, Günter; Rindi, Guido; Perren, Aurel; Komminoth, Paul; Klimstra, David S (2010). The ENETS and AJCC/UICC TNM classifications of the neuroendocrine tumors of the gastrointestinal tract and the pancreas: a statement. Virchows Archiv, 456(6), pp. 595-7. Berlin: Springer 10.1007/s00428-010-0924-6
Zini, Eric; Osto, Melania; Moretti, Simona; Franchini, Marco; Kook, Peter H; Lutz, Hans; Guscetti, Franco; Perren, Aurel; Hoelzle, Ludwig E; Ackermann, Mathias; Lutz, Thomas A; Reusch, Claudia E (2010). Hyperglycaemia but not hyperlipidaemia decreases serum amylase and increases neutrophils in the exocrine pancreas of cats. Research in veterinary science, 89(1), pp. 20-6. London: Association for Veterinary Teaching and Research Work 10.1016/j.rvsc.2010.01.006
Hantel, Constanze; Lewrick, Felicitas; Schneider, Sebastian; Zwermann, Oliver; Perren, Aurel; Reincke, Martin; Süss, Regine; Beuschlein, Felix (2010). Anti insulin-like growth factor I receptor immunoliposomes: a single formulation combining two anticancer treatments with enhanced therapeutic efficiency. Journal of clinical endocrinology and metabolism, 95(2), pp. 943-52. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2009-1980
Perren, Aurel (2010). Neuroendokrine Tumoren (NET): Aktuelle Diagnostik und Therapie. Kongress-Special(1), pp. 2-3. Zürich: Medien & Medizin Verlag MMV AG
Komminoth, Paul; Walch, Axel; Werner, Martin; Perren, Aurel (2010). Methods in Cellular and Molecular Pathology. In: Lloyd, Ricardo V. (ed.) Endocrine Pathology. Differential Diagnosis and Molecular Advances (pp. 1-44). Springer 10.1007/978-1-4419-1069-1_1
van Nederveen, Francien H; Gaal, José; Favier, Judith; Korpershoek, Esther; Oldenburg, Rogier A; de Bruyn, Elly M C A; Sleddens, Hein F B M; Derkx, Pieter; Rivière, Julie; Dannenberg, Hilde; Petri, Bart-Jeroen; Komminoth, Paul; Pacak, Karel; Hop, Wim C J; Pollard, Patrick J; Mannelli, Massimo; Bayley, Jean-Pierre; Perren, Aurel; Niemann, Stephan; Verhofstad, Albert A; ... (2009). An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis. Lancet oncology, 10(8), pp. 764-71. Oxford: Elsevier 10.1016/S1470-2045(09)70164-0
Keller, Gisela; Geist, Birgit; Slotta-Huspenina, Julia; Langer, Rupert; Nagl, Florian; Fend, Falko; Höfler, Heinz; Perren, Aurel (2009). Novel multiple, monoallelic KRAS mutations at codon 12 and 13. International journal of cancer, 125(11), pp. 2744-5. Malden, Mass.: Wiley-Blackwell 10.1002/ijc.24635
Besig, Sophie; Voland, Petra; Baur, Dorothee M; Perren, Aurel; Prinz, Christian (2009). Vascular endothelial growth factors, angiogenesis, and survival in human ileal enterochromaffin cell carcinoids. Neuroendocrinology, 90(4), pp. 402-15. Basel: Karger 10.1159/000245900
Anlauf, Martin; Bauersfeld, Juliane; Raffel, Andreas; Koch, Christian A.; Henopp, Tobias; Alkatout, Ibrahim; Schmitt, Anja; Weber, Achim; Kruse, Marie L.; Braunstein, Stefan; Kaserer, Klaus; Brauckhoff, Michael; Dralle, Henning; Moch, Holger; Heitz, Philipp U.; Komminoth, Paul; Knoefel, Wolfram T.; Perren, Aurel; Klöppel, Günter (2009). Insulinomatosis: a multicentric insulinoma disease that frequently causes early recurrent hyperinsulinemic hypoglycemia. The American journal of surgical pathology, 33(3), pp. 339-346. Lippincott Williams & Wilkins 10.1097/PAS.0b013e3181874eca
Zini, E.; Osto, M.; Franchini, M.; Guscetti, F.; Donath, M. Y.; Perren, Aurel; Heller, R. S.; Linscheid, P.; Bouwman, M.; Ackermann, M.; Lutz, T. A.; Reusch, C. E. (2009). Hyperglycaemia but not hyperlipidaemia causes beta cell dysfunction and beta cell loss in the domestic cat. Diabetologia, 52(2), pp. 336-346. Springer 10.1007/s00125-008-1201-y
Henopp, Tobias; Anlauf, Martin; Schmitt, Anja; Schlenger, Regina; Zalatnai, Attila; Couvelard, Anne; Ruszniewski, Philippe; Schaps, Klaus-Peter; Jonkers, Yvonne M. H.; Speel, Ernst-Jan M.; Pellegata, Natalia S.; Heitz, Philipp U.; Komminoth, Paul; Perren, Aurel; Klöppel, Günter (2009). Glucagon Cell Adenomatosis: A Newly Recognized Disease of the Endocrine Pancreas. Journal of clinical endocrinology and metabolism, 94(1), pp. 213-217. Endocrine Society 10.1210/jc.2008-1300
Komminoth, Paul; Perren, Aurel; van Nederveen, Francien H.; de Krijger, Ronald R. (2009). Familial endocrine tumours: phaeochromocytomas and extra-adrenal paragangliomas. Diagnostic histopathology, 15(2), pp. 61-68. Elsevier 10.1016/j.mpdhp.2009.01.003
Voland, Petra; Besig, Sophie; Rad, Roland; Braun, Thomas; Baur, Dorothee M.; Perren, Aurel; Langer, Rupert; Höfler, Heinz; Prinz, Christian (2009). Correlation of Matrix Metalloproteinases and Tissue Inhibitors of Matrix Metalloproteinase Expression in Ileal Carcinoids, Lymph Nodes and Liver Metastasis with Prognosis and Survival. Neuroendocrinology, 89(1), pp. 66-78. Karger 10.1159/000151482
Miederer, Matthias; Seidl, Stefan; Buck, Andreas; Scheidhauer, Klemens; Wester, Hans-Jürgen; Schwaiger, Markus; Perren, Aurel (2009). Correlation of immunohistopathological expression of somatostatin receptor 2 with standardised uptake values in 68Ga-DOTATOC PET/CT. European journal of nuclear medicine and molecular imaging, 36(1), pp. 48-52. Springer 10.1007/s00259-008-0944-5
Klöppel, Günter; Couvelard, Anne; Perren, Aurel; Komminoth, Paul; McNicol, Anne-Marie; Nilsson, Ola; Scarpa, Aldo; Scoazec, Jean-Yves; Wiedenmann, Bertram; Papotti, Mauro; Rindi, Guido; Plöckiger, Ursula (2009). ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: Towards a Standardized Approach to the Diagnosis of Gastroenteropancreatic Neuroendocrine Tumors and Their Prognostic Stratification. Neuroendocrinology, 90(2), pp. 162-166. Karger 10.1159/000182196
Garbrecht, N.; Anlauf, M.; Schmitt, A.; Henopp, T.; Sipos, B.; Raffel, A.; Eisenberger, C. F; Knoefel, W. T; Pavel, M.; Fottner, C.; Musholt, T. J; Rinke, A.; Arnold, R.; Berndt, U.; Plockinger, U.; Wiedenmann, B.; Moch, H.; Heitz, P. U; Komminoth, P.; Perren, Aurel; ... (2008). Somatostatin-producing neuroendocrine tumors of the duodenum and pancreas: incidence, types, biological behavior, association with inherited syndromes, and functional activity. Endocrine-related cancer, 15(1), pp. 229-241. BioScientifica Ltd. 10.1677/ERC-07-0157
Anlauf, Martin; Enosawa, Tetsuji; Henopp, Tobias; Schmitt, Anja; Gimm, Oliver; Brauckhoff, Michael; Dralle, Henning; Musil, Anette; Hauptmann, Steffen; Perren, Aurel; Klöppel, Günter (2008). Primary Lymph Node Gastrinoma or Occult Duodenal Microgastrinoma With Lymph Node Metastases in a MEN1 Patient. The American journal of surgical pathology, 32(7), pp. 1101-1105. Lippincott Williams & Wilkins 10.1097/PAS.0b013e3181655811
Schmitt Kurrer, Anja; Riniker, Florian; Anlauf, Martin; Schmid, Sonja; Soltermann, Alex; Moch, Holger; Heitz, Philipp U.; Klöppel, Günther; Komminoth, Paul; Perren, Aurel (2008). Islet 1 (Isl1) Expression is a Reliable Marker for Pancreatic Endocrine Tumors and Their Metastases. The American journal of surgical pathology, 32(3), pp. 420-425. Lippincott Williams & Wilkins 10.1097/PAS.0b013e318158a397
Klöppel, Günter; Anlauf, Martin; Raffel, Andreas; Perren, Aurel; Knoefel, Wolfram Trudo (2008). Adult diffuse nesidioblastosis: genetically or environmentally induced? Human pathology, 39(1), pp. 3-8. Elsevier 10.1016/j.humpath.2007.09.010
Schmitt Kurrer, Anja; Anlauf, Martin; Rousson, Valentin; Schmid, Sonja; Kofler, Andreas; Riniker, Florian; Bauersfeld, Juliane; Barghorn, Andre; Probst-Hensch, Nicole M.; Moch, Holger; Heitz, Philipp U.; Kloeppel, Guenter; Komminoth, Paul; Perren, Aurel (2007). WHO 2004 Criteria and CK19 are Reliable Prognostic Markers in Pancreatic Endocrine Tumors. The American journal of surgical pathology, 31(11), pp. 1677-1682. Lippincott Williams & Wilkins 10.1097/PAS.0b013e31805f675d
Lehmann, R.; Zuellig, R. A.; Kugelmeier, P.; Baenninger, P. B.; Moritz, W.; Perren, Aurel; Clavien, P.-A.; Weber, M.; Spinas, G. A. (2007). Superiority of Small Islets in Human Islet Transplantation. Diabetes, 56(3), pp. 594-603. American Diabetes Association 10.2337/db06-0779
Klöppel, Günter; Rindi, Guido; Anlauf, Martin; Perren, Aurel; Komminoth, Paul (2007). Site-specific biology and pathology of gastroenteropancreatic neuroendocrine tumors. Virchows Archiv, 451(S1), pp. 9-27. Springer 10.1007/s00428-007-0461-0
Perren, Aurel; Anlauf, Martin; Henopp, Tobias; Rudolph, Thomas; Schmitt, Anja; Raffel, Andreas; Gimm, Oliver; Weihe, Eberhard; Knoefel, Wolfram T.; Dralle, Henning; Heitz, Philipp U.; Komminoth, Paul; Klöppel, Günter (2007). Multiple Endocrine Neoplasia Type 1 (MEN1): Loss of One MEN1 Allele in Tumors and Monohormonal Endocrine Cell Clusters But Not in Islet Hyperplasia of the Pancreas. Journal of clinical endocrinology and metabolism, 92(3), pp. 1118-1128. Endocrine Society 10.1210/jc.2006-1944
Perren, Aurel; Anlauf, Martin; Komminoth, Paul (2007). Molecular profiles of gastroenteropancreatic endocrine tumors. Virchows Archiv, 451(S1), pp. 39-46. Springer 10.1007/s00428-007-0449-9
Ehses, J. A.; Perren, Aurel; Eppler, E.; Ribaux, P.; Pospisilik, J. A.; Maor-Cahn, R.; Gueripel, X.; Ellingsgaard, H.; Schneider, M. K.J.; Biollaz, G.; Fontana, A.; Reinecke, M.; Homo-Delarche, F.; Donath, M. Y. (2007). Increased Number of Islet-Associated Macrophages in Type 2 Diabetes. Diabetes, 56(9), pp. 2356-2370. American Diabetes Association 10.2337/db06-1650
Anlauf, Martin; Garbrecht, Nele; Bauersfeld, Juliane; Schmitt, Anja; Henopp, Tobias; Komminoth, Paul; Heitz, Philipp U.; Perren, Aurel; Klöppel, Günter (2007). Hereditary neuroendocrine tumors of the gastroenteropancreatic system. Virchows Archiv, 451(S1), pp. 29-38. Springer 10.1007/s00428-007-0450-3
Anlauf, M; Perren, Aurel; Henopp, T; Rudolf, T; Garbrecht, N; Schmitt, A; Raffel, A; Gimm, O; Weihe, E; Knoefel, W T; Dralle, H; Heitz, P. U; Komminoth, P; Kloppel, G (2007). Allelic deletion of the MEN1 gene in duodenal gastrin and somatostatin cell neoplasms and their precursor lesions. Gut, 56(5), pp. 637-644. BMJ Publishing Group 10.1136/gut.2006.108910
Anlauf, Martin; Schlenger, Regina; Perren, Aurel; Bauersfeld, Juliane; Koch, Christian A.; Dralle, Henning; Raffel, Andreas; Knoefel, Wolfram T.; Weihe, Eberhard; Ruszniewski, Philippe; Couvelard, Anne; Komminoth, Paul; Heitz, Philipp U.; Klöppel, Günter (2006). Microadenomatosis of the Endocrine Pancreas in Patients With and Without the Multiple Endocrine Neoplasia Type 1 Syndrome. The American journal of surgical pathology, 30(5), pp. 560-574. Lippincott Williams & Wilkins 10.1097/01.pas.0000194044.01104.25
Maier-Woelfle, Margarete; Brändle, Michael; Komminoth, Paul; Saremaslani, Parvin; Schmid, Sonja; Locher, Tamara; Heitz, Philipp U; Krull, Ina; Galeazzi, Renato L; Schmid, Christoph; Perren, Aurel (2004). A novel succinate dehydrogenase subunit B gene mutation, H132P, causes familial malignant sympathetic extraadrenal paragangliomas. Journal of clinical endocrinology and metabolism, 89(1), pp. 362-7. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2003-031236
