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Radu, Pompilia; Becchetti, Chiara; Schropp, Jonas; Schmid, Patrick; Künzler-Heule, Patrizia; Mertens, Joachim; Moradpour, Darius; Müllaupt, Beat; Semela, David; Negro, Francesco; Heim, Markus; Clerc, Olivier; Roelens, Maroussia; Keiser, Olivia; Berzigotti, Annalisa (2024). Effect of Direct Acting Antiviral Drugs on the Occurrence and Recurrence of Intra- and Extra-Hepatic Malignancies in Patients with Chronic Hepatitis C Virus Infection. Cancers, 16(14) MDPI AG 10.3390/cancers16142573
Sawatzki, Mikael; Burkart, Thomas; Baumeler, Stephan; Semela, David; Dong, Yi; Jenssen, Christian; Srivastava, David; Dietrich, Christoph F (2024). Ultrasound Doppler technique for the diagnosis of focal nodular hyperplasia - case series and systematic review. Medical ultrasonography, 26(1), pp. 72-82. SRUMB 10.11152/mu-4301
Wiegand, Nico; Geyer, Martin; Lollo, Gianluca; Wuillemin, Walter A; Aepli, Patrick; Frei, Remus; Godat, Sébastien; Manz, Michael; Seewald, Stefan; The, Frans Olivier; Wiest, Reiner; Borovicka, Jan; Brand, Stephan; Buyse, Sophie; Degen, Lukas; Ehmann, Tobias; Riniker, Florian; Riva, Daniele; Semela, David; Truninger, Kaspar; ... (2023). Antithrombotic therapy and assessment for bleeding diathesis in elective gastrointestinal endoscopy - Expert Opinion Statement on behalf of the Swiss Society of Gastroenterology. Praxis - schweizerische Rundschau für Medizin, 112(13), pp. 635-641. Huber
Ludz, Christine; Stirnimann, Guido; Semela, David; Mertens, Joachim; Kremer, Andreas E.; Filipowicz Sinnreich, Magdalena; Sokollik, Christiane; Bernsmeier, Christine; Bresson-Hadni, Solange; McLin, Valérie; Rock, Nathalie; Braegger, Christian; Posovszky, Carsten; Müller, Pascal; Cremer, Matthias; De Gottardi, Andrea; Galante, Antonio; Furlano, Raoul; Righini-Grunder, Franziska; Becker, Björn; ... (2023). Epidemiology, clinical features and management of autoimmune hepatitis in Switzerland: a retrospective and prospective cohort study. Swiss medical weekly, 153(8), p. 40102. SMW supporting association 10.57187/smw.2023.40102
Purde, Mette‑Triin; Niederer, Rebekka; Wagner, ikolaus B.; Diem, Stefan; Berner, Fiamma; Hasan Ali, Omar; Hillmann, Dorothea; Bergamin, Irina; Joerger, Markus; Risch, Martin; Niederhauser, Christoph; Lenz, Tobias L.; Früh, Martin; Risch, Lorenz; Semela, David; Flatz, Lukas (2022). Presence of autoantibodies in serum does not impact the occurrence of immune checkpoint inhibitor-induced hepatitis in a prospective cohort of cancer patients. Journal of cancer research and clinical oncology, 148(3), pp. 647-656. Springer 10.1007/s00432-021-03870-6
Bihl, Florian; Bruggmann, Philip; Castro Batänjer, Erika; Dufour, Jean-François; Lavanchy, Daniel; Müllhaupt, Beat; Negro, Francesco; Razavi, Homie; Scheidegger, Claude; Semela, David; Semmo, Nasser; Blach, Sarah (2022). HCV disease burden and population segments in Switzerland. Liver international, 42(2), pp. 330-339. Wiley 10.1111/liv.15111
Sawatzki, Mikael; Güller, Ulrich; Güsewell, Sabine; Husarik, Daniela B; Semela, David; Brand, Stephan (2021). Contrast-enhanced ultrasound can guide the therapeutic strategy by improving the detection of colorectal liver metastases. Journal of hepatology, 74(2), pp. 419-427. Elsevier 10.1016/j.jhep.2020.09.036
Müllhaupt, Beat; Semela, David; Ruckstuhl, Lisa; Magenta, Lorenzo; Clerc, Olivier; Torgler, Ralph; Negro, Francesco; Semmo, Nasser (2021). Real-world effectiveness and safety of glecaprevir/pibrentasvir therapy in patients with chronic hepatitis C virus infection in Switzerland. Swiss medical weekly, 151, w20399. EMH Media 10.4414/smw.2021.20399
Terziroli Beretta-Piccoli, Benedetta; Stirnimann, Guido; Mertens, Joachim; Semela, David; Zen, Yoh; Mazzucchelli, Luca; Voreck, Anja; Kolbus, Norbert; Merlo, Elisabetta; Di Bartolomeo, Claudia; Messina, Paola; Cerny, Andreas; Costantini, Silvia; Vergani, Diego; Mieli-Vergani, Giorgina (2021). Primary biliary cholangitis with normal alkaline phosphatase: A neglected clinical entity challenging current guidelines. Journal of autoimmunity, 116(102578), p. 102578. Elsevier 10.1016/j.jaut.2020.102578
Roelens, Maroussia; Bertisch, Barbara; Moradpour, Darius; Cerny, Andreas; Semmo, Nasser; Schmid, Patrick; Mülhaupt, Beat; Clerc, Olivier; Semela, David; Junker, Christoph; Negro, Francesco; Keiser, Olivia; Hepatitis C Cohort Study, Swiss (2020). All-Cause Mortality and Causes of Death in the Swiss Hepatitis C Cohort Study (SCCS). Open Forum Infectious Diseases, 7(8), ofaa308. Oxford University Press 10.1093/ofid/ofaa308
Semmo, Nasser; Müllhaupt, Beat; Ruckstuhl, Lisa; Magenta, Lorenzo; Clerc, Olivier; Torgler, Ralph; Semela, David (2020). A prospective, multicenter, post-marketing observational study to measure the quality of life of HCV genotype 1 infected, treatment naïve patients suffering from fatigue and receiving 3D regimen: The HEMATITE study. PLoS ONE, 15(11), e0241267. Public Library of Science 10.1371/journal.pone.0241267
Goossens, Nicolas; Bellentani, Stefano; Cerny, Andreas; Dufour, Jean-François; Jornayvaz, François R; Mertens, Joachim; Moriggia, Alberto; Muellhaupt, Beat; Negro, Francesco; Razavi, Homie; Semela, David; Estes, Chris (2019). Nonalcoholic fatty liver disease burden - Switzerland 2018-2030. Swiss medical weekly, 149, w20152. EMH Media 10.4414/smw.2019.20152
Terziroli Beretta-Piccoli, Benedetta; Di Bartolomeo, Claudia; Deleonardi, Gaia; Grondona, Ana Gabriela; Silvestri, Tania; Tesei, Cinzia; Melidona, Laura; Cerny, Andreas; Mertens, Joachim; Semmo, Nasser; Semela, David; Moradpour, Darius; Mieli-Vergani, Giorgina; Vergani, Diego; Muratori, Luigi (2019). Autoimmune liver serology before and after successful treatment of chronic hepatitis C by direct acting antiviral agents. Journal of autoimmunity, 102, pp. 89-95. Elsevier 10.1016/j.jaut.2019.04.019
Dimova, Ivanka; Karthik, Swapna; Makanya, Andrew; Hlushchuk, Ruslan; Semela, David; Volarevic, Vladislav; Djonov, Valentin (2019). SDF-1/CXCR4 signalling is involved in blood vessel growth and remodelling by intussusception. Journal of Cellular and Molecular Medicine, 23(6), pp. 3916-3926. Wiley 10.1111/jcmm.14269
De Gottardi, Andrea; Rautou, Pierre-Emmanuel; Schouten, Jeoffrey; Rubbia-Brandt, Laura; Leebeek, Frank; Trebicka, Jonel; Murad, Sarwa Darwish; Vilgrain, Valérie; Hernandez-Gea, Virginia; Nery, Filipe; Plessier, Aurélie; Berzigotti, Annalisa; Bioulac-Sage, Paulette; Primignani, Massimo; Semela, David; Elkrief, Laure; Bedossa, Pierre; Valla, Dominique; Garcia-Pagan, Juan Carlos (2019). Porto-sinusoidal vascular disease: proposal and description of a novel entity. The lancet. Gastroenterology & hepatology, 4(5), pp. 399-411. Elsevier 10.1016/S2468-1253(19)30047-0
About, Frédégonde; Bibert, Stéphanie; Jouanguy, Emmanuelle; Nalpas, Bertrand; Lorenzo, Lazaro; Rattina, Vimel; Zarhrate, Mohammed; Hanein, Sylvain; Munteanu, Mona; Müllhaupt, Beat; Semela, David; Semmo, Nasser; Casanova, Jean-Laurent; Theodorou, Ioannis; Sultanik, Philippe; Poynard, Thierry; Pol, Stanislas; Bochud, Pierre-Yves; Cobat, Aurélie and Abel, Laurent (2019). Identification of an Endoglin Variant Associated With HCV-Related Liver Fibrosis Progression by Next-Generation Sequencing. Frontiers in genetics, 10(1024), p. 1024. Frontiers Media SA 10.3389/fgene.2019.01024
Brezzi, Matteo; Bertisch, Barbara; Roelens, Maroussia; Moradpour, Darius; Terziroli Beretta-Piccoli, Benedetta; Semmo, Nasser; Müllhaupt, Beat; Semela, David; Negro, Francesco; Keiser, Olivia (2019). Impact of geographic origin on access to therapy and therapy outcomes in the Swiss Hepatitis C Cohort Study. PLoS ONE, 14(6), e0218706. Public Library of Science 10.1371/journal.pone.0218706
Geier, Andreas; Eichinger, Mareile; Stirnimann, Guido; Semela, David; Tay, Fabian; Seifert, Burkhardt; Tschopp, Oliver; Bantel, Heike; Jahn, Daniel; Marques Maggio, Ewerton; Saleh, Lanja; Bischoff-Ferrari, Heike A; Müllhaupt, Beat; Dufour, Jean-François (2018). Treatment of non-alcoholic steatohepatitis patients with vitamin D: a double-blinded, randomized, placebo-controlled pilot study. Scandinavian journal of gastroenterology, 53(9), pp. 1114-1120. Taylor & Francis 10.1080/00365521.2018.1501091
Terziroli Beretta-Piccoli, Benedetta; Stirnimann, Guido; Cerny, Andreas; Semela, David; Hessler, Roxane; Helbling, Beat; Stickel, Felix; Kalid-de Bakker, Carolina; Bihl, Florian; Giostra, Emiliano; Filipowicz Sinnreich, Magdalena; Oneta, Carl; Baserga, Adriana; Invernizzi, Pietro; Carbone, Marco; Mertens, Joachim (2018). Geoepidemiology of Primary Biliary Cholangitis: Lessons from Switzerland. Clinical reviews in allergy & immunology, 54(2), pp. 295-306. Humana Press 10.1007/s12016-017-8656-x
Bruggmann, Philip; Blach, Sarah; Deltenre, Pierre; Fehr, Jan; Kouyos, Roger; Lavanchy, Daniel; Müllhaupt, Beat; Rauch, Andri; Razavi, Homie; Schmid, Patrick; Semela, David; Stoeckle, Marcel; Negro, Franco (2017). Hepatitis C virus dynamics among intravenous drug users suggest that an annual treatment uptake above 10% would eliminate the disease by 2030. Swiss medical weekly, 147(w14543), w14543. EMH Schweizerischer Ärzteverlag 10.4414/smw.2017.14543
Kolly, Philippe; Waidmann, Oliver; Vermehren, Johannes; Moreno, Christophe; Vögeli, Isabelle; Berg, Thomas; Semela, David; Zeuzem, Stefan; Dufour, Jean-François (2017). Hepatocellular carcinoma recurrence after direct antiviral agent treatment: A European multicentre study. Journal of hepatology, 67(4), pp. 876-878. Elsevier 10.1016/j.jhep.2017.07.007
Gauthiez, Emeline; Habfast-Robertson, Ines; Rüeger, Sina; Kutalik, Zoltan; Aubert, Vincent; Berg, Thomas; Cerny, Andreas; Gorgievski, Meri; George, Jacob; Heim, Markus H; Malinverni, Raffaele; Moradpour, Darius; Müllhaupt, Beat; Negro, Francesco; Semela, David; Semmo, Nasser; Villard, Jean; Bibert, Stéphanie; Bochud, Pierre-Yves (2017). A systematic review and meta-analysis of HCV clearance. Liver international, 37(10), pp. 1431-1445. Wiley 10.1111/liv.13401
De Gottardi, Andrea; Trebicka, Jonel; Klinger, Christoph; Plessier, Aurélie; Seijo, Susana; Terziroli, Benedetta; Magenta, Lorenzo; Semela, David; Buscarini, Elisabetta; Langlet, Philippe; Görtzen, Jan; Puente, Angela; Müllhaupt, Beat; Navascuès, Carmen; Nery, Filipe; Deltenre, Pierre; Turon, Fanny; Engelmann, Cornelius; Arya, Rupen; Caca, Karel; ... (2017). Antithrombotic treatment with direct-acting oral anticoagulants in patients with splanchnic vein thrombosis and cirrhosis. Liver international, 37(5), pp. 694-699. Wiley 10.1111/liv.13285
Wang, Hui; El Maadidi, Souhayla; Fischer, Janett; Grabski, Elena; Dickhöfer, Sabine; Klimosch, Sascha; Flannery, Sinead M; Filomena, Angela; Wolz, Olaf-Oliver; Schneiderhan-Marra, Nicole; Löffler, Markus W; Wiese, Manfred; Pichulik, Tica; Müllhaupt, Beat; Semela, David; Dufour, Jean-François; Bochud, Pierre-Yves; Bowie, Andrew G; Kalinke, Ulrich; Berg, Thomas; ... (2015). A frequent hypofunctional IRAK2 variant is associated with reduced spontaneous hepatitis C virus clearance. Hepatology, 62(5), pp. 1375-1387. Wiley Interscience 10.1002/hep.28105
Terczyńska-Dyla, Ewa; Bibert, Stephanie; Duong, Francois H T; Krol, Ilona; Jørgensen, Sanne; Collinet, Emilie; Kutalik, Zoltán; Aubert, Vincent; Cerny, Andreas; Kaiser, Laurent; Malinverni, Raffaele; Mangia, Alessandra; Moradpour, Darius; Müllhaupt, Beat; Negro, Francesco; Santoro, Rosanna; Semela, David; Semmo, Nasser; Heim, Markus H; Bochud, Pierre-Yves; ... (2015). Corrigendum: reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes. Nature communications, 6, p. 7280. Nature Publishing Group 10.1038/ncomms8280
Rothweiler, Sonja; Dill, Michael T; Terracciano, Luigi; Makowska, Zuzanna; Quagliata, Luca; Hlushchuk, Ruslan; Djonov, Valentin; Heim, Markus H; Semela, David (2014). Generation of a murine hepatic angiosarcoma cell line and reproducible mouse tumor model. Laboratory investigation, 95(3), pp. 351-362. Nature Publishing Group 10.1038/labinvest.2014.141
Terczyńska-Dyla, Ewa; Bibert, Stephanie; Duong, Francois H. T.; Krol, Ilona; Jørgensen, Sanne; Collinet, Emilie; Kutalik, Zoltán; Aubert, Vincent; Cerny, Andreas; Kaiser, Laurent; Malinverni, Raffaele; Mangia, Alessandra; Moradpour, Darius; Müllhaupt, Beat; Negro, Francesco; Santoro, Rosanna; Semela, David; Semmo, Nasser; Rubbia-Brandt, Laura; Martinetti, Gladys; ... (2014). Reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes. Nature communications, 5, p. 5699. Nature Publishing Group 10.1038/ncomms6699
Morard, Isabelle; Clément, Sophie; Calmy, Alexandra; Mangia, Alessandra; Cerny, Andrea; De Gottardi, Andrea; Gorgievski, Meri; Heim, Markus; Malinverni, Raffaele; Moradpour, Darius; Müllhaupt, Beat; Semela, David; Pascarella, Stéphanie; Bochud, Pierre-Yves; Negro, Franco (2014). Clinical significance of the CCR5delta32 allele in hepatitis C. PLoS ONE, 9(9), e106424. Public Library of Science 10.1371/journal.pone.0106424
Rau, Monika; Stickel, Felix; Russmann, Stefan; Manser, Christine N; Becker, Philip P; Weisskopf, Michael; Schmitt, Johannes; Dill, Michael T; Dufour, Jean-François; Moradpour, Darius; Semela, David; Müllhaupt, Beat; Geier, Andreas; Swiss Hepatitis C Cohort Study Group (SCCS), (2013). Impact of genetic SLC28 transporter and ITPA variants on ribavirin serum level, hemoglobin drop and therapeutic response in patients with HCV infection. Journal of hepatology, 58(4), pp. 669-75. Amsterdam: Elsevier 10.1016/j.jhep.2012.11.027
Dimova, Ivanka; Hlushchuk, Ruslan; Makanya, Andrew; Styp, Beata; Ceausu, Amalia; Flueckiger, Stefanie; Lang, Sonja; Semela, David; Le Noble, Ferdinand; Chatterjee, Suvro; Djonov, Valentin (2013). Inhibition of Notch signaling induces extensive intussusceptive neo-angiogenesis by recruitment of mononuclear cells. Angiogenesis, 16(4), pp. 921-937. Springer Netherlands 10.1007/s10456-013-9366-5
Lange, Christian M.; Miki, Daiki; Ochi, Hidenori; Nischalke, Hans-Dieter; Bojunga, Jörg; Bibert, Stéphanie; Morikawa, Kenichi; Gouttenoire, Jérôme; Cerny, Andreas; Dufour, Jean-François; Gorgievski, Meri; Heim, Markus H.; Malinverni, Raffaele; Müllhaupt, Beat; Negro, Francesco; Semela, David; Kutalik, Zoltan; Müller, Tobias; Spengler, Ulrich; Berg, Thomas; ... (2013). Genetic Analyses Reveal a Role for Vitamin D Insufficiency in HCV-Associated Hepatocellular Carcinoma Development. PLoS ONE, 8(5), e64053. Public Library of Science 10.1371/journal.pone.0064053
Lange, Christian M.; Bibert, Stéphanie; Dufour, Jean-François; Cellerai, Cristina; Cerny, Andreas; Heim, Markus H.; Kaiser, Laurent; Malinverni, Raffaele; Müllhaupt, Beat; Negro, Francesco; Semela, David; Moradpour, Darius; Kutalik, Zoltán; Bochud, Pierre-Yves (2013). Comparative genetic analyses point to HCP5 as susceptibility locus for HCV-associated hepatocellular carcinoma. Journal of hepatology, 59(3), pp. 504-509. Elsevier 10.1016/j.jhep.2013.04.032
Dill, Michael T; Rothweiler, Sonja; Djonov, Valentin; Hlushchuk, Ruslan; Tornillo, Luigi; Terracciano, Luigi; Meili-Butz, Silvia; Radtke, Freddy; Heim, Markus H; Semela, David (2012). Disruption of Notch1 induces vascular remodeling, intussusceptive angiogenesis, and angiosarcomas in livers of mice. Gastroenterology, 142(4), 967-977.e2. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2011.12.052
Kuske, Lorenz; Mensen, Armand; Müllhaupt, Beat; Negro, Francesco; Semela, David; Moradpour, Darius; Malé, Pierre Jean; Heim, Markus H; Malinverni, Raffaele; Cerny, Andreas; Dufour, Jean-François; Swiss Hepatitis C Cohort Study, (2012). Characteristics of patients with chronic hepatitis C who develop hepatocellular carcinoma. Swiss medical weekly, 142, w13651. Muttenz: EMH Schweizerischer Ärzteverlag 10.4414/smw.2012.13651
Patin, Etienne; Kutalik, Zoltán; Guergnon, Julien; Bibert, Stéphanie; Nalpas, Bertrand; Jouanguy, Emmanuelle; Munteanu, Mona; Bousquet, Laurence; Argiro, Laurent; Halfon, Philippe; Boland, Anne; Müllhaupt, Beat; Semela, David; Dufour, Jean-François; Heim, Markus H; Moradpour, Darius; Cerny, Andreas; Malinverni, Raffaele; Hirsch, Hans; Martinetti, Gladys; ... (2012). Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection. Gastroenterology, 143(5), 1244-52.e1-12. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2012.07.097
Piguet, Anne-Christine; Semela, David; Keogh, Adrian; Wilkens, Ludwig; Stroka, Deborah; Stoupis, Christoforos; St-Pierre, Marie V; Dufour, Jean-François (2008). Inhibition of mTOR in combination with doxorubicin in an experimental model of hepatocellular carcinoma. Journal of hepatology, 49(1), pp. 78-87. Amsterdam: Elsevier 10.1016/j.jhep.2008.03.024
Chtioui, Haithem; Semela, David; Ledermann, Monika; Zimmermann, Arthur; Dufour, Jean-François (2007). Expression and activity of the cytochrome P450 2E1 in patients with nonalcoholic steatosis and steatohepatitis. Liver international, 27(6), pp. 764-71. Oxford: Blackwell Munksgaard 10.1111/j.1478-3231.2007.01524.x
Semela, David; Piguet, Anne-Christine; Kolev, Mirjam; Schmitter, Karin; Hlushchuk, Ruslan; Djonov, Valentin; Stoupis, Christoforos; Dufour, Jean-François (2007). Vascular remodeling and antitumoral effects of mTOR inhibition in a rat model of hepatocellular carcinoma. Journal of hepatology, 46(5), pp. 840-8. Amsterdam: Elsevier 10.1016/j.jhep.2006.11.021
Martin, Juliette; Magnino, Fabrice; Schmidt, Karin; Piguet, Anne-Christine; Lee, Ju-Seog; Semela, David; St-Pierre, Marie V; Ziemiecki, Andrew; Cassio, Doris; Brenner, Charles; Thorgeirsson, Snorri S; Dufour, Jean-François (2006). Hint2, a mitochondrial apoptotic sensitizer down-regulated in hepatocellular carcinoma. Gastroenterology, 130(7), pp. 2179-88. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2006.03.004
Costantini, Silvia; Cerny, Andreas; Stirnimann, Guido; Sinnreich, Magdalena Filipowicz; Mertens, Joachim C.; Semela, David; Baserga, Adriana; Bellentani, Stefano; Merlo, Elisabetta; Mieli-Vergani, Giorgina; Vergani, Diego; Terziroli, Benedetta (2020). Histological primary biliary cholangitis changes in patients with positive serology and normal alkaline phosphatase. Journal of hepatology, 73(S1), S461-S462. Elsevier 10.1016/S0168-8278(20)31406-9
