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Naseem, Madiha; Cao, Shu; Yang, Dongyun; Millstein, Joshua; Puccini, Alberto; Loupakis, Fotios; Stintzing, Sebastian; Cremolini, Chiara; Tokunaga, Ryuma; Battaglin, Francesca; Soni, Shivani; Berger, Martin D.; Barzi, Afsaneh; Zhang, Wu; Falcone, Alfredo; Heinemann, Volker; Lenz, Heinz-Josef (2021). Random survival forests identify pathways with polymorphisms predictive of survival in KRAS mutant and KRAS wild-type metastatic colorectal cancer patients. Scientific reports, 11(1), p. 12191. Springer Nature 10.1038/s41598-021-91330-z
Volz, Nico B; Hanna, Diana L; Stintzing, Sebastian; Zhang, Wu; Yang, Dongyun; Cao, Shu; Ning, Yan; Matsusaka, Satoshi; Sunakawa, Yu; Berger, Martin D.; Cremolini, Chiara; Loupakis, Fotios; Falcone, Alfredo; Lenz, Heinz-Josef (2020). Polymorphisms within Immune Regulatory Pathways Predict Cetuximab Efficacy and Survival in Metastatic Colorectal Cancer Patients. Cancers, 12(10) MDPI AG 10.3390/cancers12102947
Suenaga, Mitsukuni; Schirripa, Marta; Cao, Shu; Zhang, Wu; Yang, Dongyun; Cremolini, Chiara; Murgioni, Sabina; Lonardi, Sara; Ning, Yan; Okazaki, Satoshi; Berger, Martin D.; Miyamoto, Yuji; Barzi, Afsaneh; Loupakis, Fotios; Falcone, Alfredo; Lenz, Heinz-Josef (2020). Single Nucleotide Polymorphisms in MiRNA Binding Sites of Nucleotide Excision Repair-Related Genes Predict Clinical Benefit of Oxaliplatin in FOLFOXIRI Plus Bevacizumab: Analysis of the TRIBE Trial. Cancers, 12(7) MDPI AG 10.3390/cancers12071742
Berger, Martin D.; Ning, Yan; Stintzing, Sebastian; Heinemann, Volker; Cao, Shu; Zhang, Wu; Yang, Dongyun; Miyamoto, Yuji; Suenaga, Mitsukuni; Schirripa, Marta; Hanna, Diana L; Soni, Shivani; Puccini, Alberto; Tokunaga, Ryuma; Naseem, Madiha; Battaglin, Francesca; Cremolini, Chiara; Falcone, Alfredo; Loupakis, Fotios and Lenz, Heinz-Josef (2020). A polymorphism within the R-spondin 2 gene predicts outcome in metastatic colorectal cancer patients treated with FOLFIRI/bevacizumab: data from FIRE-3 and TRIBE trials. European journal of cancer, 131, pp. 89-97. Elsevier 10.1016/j.ejca.2020.02.048
Matsusaka, Satoshi; Hanna, Diana L; Ning, Yan; Yang, Dongyun; Cao, Shu; Berger, Martin D.; Miyamoto, Yuji; Suenaga, Mitsukuni; Dan, Shingo; Mashima, Tetsuo; Seimiya, Hiroyuki; Zhang, Wu; Lenz, Heinz-Josef (2020). Epidermal growth factor receptor mRNA expression: A potential molecular escape mechanism from regorafenib. Cancer science, 111(2), pp. 441-450. Wiley 10.1111/cas.14273
Miyamoto, Yuji; Schirripa, Marta; Suenaga, Mitsukuni; Cao, Shu; Zhang, Wu; Okazaki, Satoshi; Berger, Martin D.; Matsusaka, Satoshi; Yang, Dongyun; Ning, Yan; Baba, Hideo; Loupakis, Fotios; Lonardi, Sara; Pietrantonio, Filippo; Borelli, Beatrice; Cremolini, Chiara; Yamaguchi, Toshiharu; Lenz, Heinz-Josef (2020). A polymorphism in the cachexia-associated gene INHBA predicts efficacy of regorafenib in patients with refractory metastatic colorectal cancer. PLoS ONE, 15(9), e0239439. Public Library of Science 10.1371/journal.pone.0239439
Suenaga, Mitsukuni; Cao, Shu; Zhang, Wu; Yang, Dongyun; Ning, Yan; Okazaki, Satoshi; Berger, Martin Dave; Miyamoto, Yuji; Schirripa, Marta; Soni, Shivani; Barzi, Afsaneh; Yamaguchi, Toshiharu; Lenz, Heinz-Josef (2019). Genetic variants in CCL5 and CCR5 genes and serum VEGF-A levels predict efficacy of bevacizumab in metastatic colorectal cancer patients. International journal of cancer, 144(10), pp. 2567-2577. Wiley-Blackwell 10.1002/ijc.31968
Suenaga, Mitsukuni; Stintzing, Sebastian; Cao, Shu; Zhang, Wu; Yang, Dongyun; Ning, Yan; Okazaki, Satoshi; Berger, Martin Dave; Miyamoto, Yuji; Schirripa, Marta; Soni, Shivani; Barzi, Afsaneh; Heinemann, Volker; Lenz, Heinz-Josef (2019). Role of CCL5 and CCR5 gene polymorphisms in epidermal growth factor receptor signalling blockade in metastatic colorectal cancer: analysis of the FIRE-3 trial. European journal of cancer, 107, pp. 100-114. Elsevier 10.1016/j.ejca.2018.11.019
Suenaga, Mitsukuni; Schirripa, Marta; Cao, Shu; Zhang, Wu; Yang, Dongyun; Cremolini, Chiara; Lonardi, Sara; Bergamo, Francesca; Ning, Yang; Yamamoto, Noriko; Okazaki, Satoshi; Berger, Martin Dave; Miyamoto, Yuji; Gopez, Roel; Barzi, Afsaneh; Yamaguchi, Toshiharu; Stintzing, Sebastian; Heinemann, Volker; Loupakis, Fotios; Falcone, Alfredo; ... (2018). Potential role of PIN1 genotypes in predicting benefit from oxaliplatin-based and irinotecan-based treatment in patients with metastatic colorectal cancer. The pharmacogenomics journal, 18(5), pp. 623-632. Nature Publishing Group 10.1038/s41397-018-0030-8
Hanna, Diana L; Loupakis, Fotios; Yang, Dongyun; Cremolini, Chiara; Schirripa, Marta; Li, Meng; Matsusaka, Satoshi; Berger, Martin Dave; Miyamoto, Yuji; Zhang, Wu; Ning, Yan; Antoniotti, Carlotta; Salvatore, Lisa; Moran, Miriana; Zeger, Gary; Astrow, Stephanie H; Falcone, Alfredo; Lenz, Heinz-Josef (2018). Prognostic Value of ACVRL1 Expression in Metastatic Colorectal Cancer Patients Receiving First-line Chemotherapy With Bevacizumab: Results From the Triplet Plus Bevacizumab (TRIBE) Study. Clinical colorectal cancer, 17(3), e471-e488. Elsevier 10.1016/j.clcc.2018.03.006
Suenaga, Mitsukuni; Schirripa, Marta; Cao, Shu; Zhang, Wu; Yang, Dongyun; Ning, Yan; Cremolini, Chiara; Antoniotti, Carlotta; Borelli, Beatrice; Mashima, Tetsuo; Okazaki, Satoshi; Berger, Martin Dave; Miyamoto, Yuji; Gopez, Roel; Barzi, Afsaneh; Lonardi, Sara; Yamaguchi, Toshiharu; Falcone, Alfredo; Loupakis, Fotios and Lenz, Heinz-Josef (2018). Gene Polymorphisms in the CCL5/CCR5 Pathway as a Genetic Biomarker for Outcome and Hand-Foot Skin Reaction in Metastatic Colorectal Cancer Patients Treated With Regorafenib. Clinical colorectal cancer, 17(2), e395-e414. Elsevier 10.1016/j.clcc.2018.02.010
Berger, Martin Dave; Stintzing, Sebastian; Heinemann, Volker; Cao, Shu; Yang, Dongyun; Sunakawa, Yu; Matsusaka, Satoshi; Ning, Yan; Okazaki, Satoshi; Miyamoto, Yuji; Suenaga, Mitsukuni; Schirripa, Marta; Hanna, Diana L; Soni, Shivani; Puccini, Alberto; Zhang, Wu; Cremolini, Chiara; Falcone, Alfredo; Loupakis, Fotios and Lenz, Heinz-Josef (2018). A Polymorphism within the Vitamin D Transporter Gene Predicts Outcome in Metastatic Colorectal Cancer Patients Treated with FOLFIRI/Bevacizumab or FOLFIRI/Cetuximab. Clinical cancer research, 24(4), pp. 784-793. American Association for Cancer Research 10.1158/1078-0432.CCR-17-1663
Schirripa, Marta; Zhang, Wu; Yang, Dongyun; Cao, Shu; Okazaki, Satoshi; Loupakis, Fotios; Berger, Martin Dave; Ning, Yan; Miyamoto, Yuji; Suenaga, Mitsukuni; Alberti, Giulia; West, Jordan D; Lonardi, Sara; Khoukaz, Taline; Bergamo, Francesca; Battaglin, Francesca; Antoniotti, Carlotta; Falcone, Alfredo; Stintzing, Sebastian; Heinemann, Volker; ... (2018). NOS2 polymorphisms in prediction of benefit from first-line chemotherapy in metastatic colorectal cancer patients. PLoS ONE, 13(3), e0193640. Public Library of Science 10.1371/journal.pone.0193640
Okazaki, Satoshi; Schirripa, Marta; Loupakis, Fotios; Cao, Shu; Zhang, Wu; Yang, Dongyun; Ning, Yan; Berger, Martin Dave; Miyamoto, Yuji; Suenaga, Mitsukuni; Iqubal, Syma; Barzi, Afsaneh; Cremolini, Chiara; Falcone, Alfredo; Battaglin, Francesca; Salvatore, Lisa; Borelli, Beatrice; Helentjaris, Timothy G; Lenz, Heinz-Josef (2017). Tandem repeat variation near the HIC1 (hypermethylated in cancer 1) promoter predicts outcome of oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer. Cancer, 123(22), pp. 4506-4514. John Wiley & Sons 10.1002/cncr.30880
Suenaga, Mitsukuni; Schirripa, Marta; Cao, Shu; Zhang, Wu; Yang, Dongyun; Dadduzio, Vincenzo; Salvatore, Lisa; Borelli, Beatrice; Pietrantonio, Filippo; Ning, Yan; Okazaki, Satoshi; Berger, Martin Dave; Miyamoto, Yuji; Gopez, Roel; Barzi, Afsaneh; Yamaguchi, Toshiharu; Loupakis, Fotios; Lenz, Heinz-Josef (2017). Potential role of polymorphisms in the transporter genes ENT1 and MATE1/OCT2 in predicting TAS-102 efficacy and toxicity in patients with refractory metastatic colorectal cancer. European journal of cancer, 86, pp. 197-206. Elsevier 10.1016/j.ejca.2017.08.033
Okazaki, Satoshi; Stintzing, Sebastian; Sunakawa, Yu; Cao, Shu; Zhang, Wu; Yang, Dongyun; Ning, Yan; Matsusaka, Satoshi; Berger, Martin Dave; Miyamoto, Yuji; Suenaga, Mitsukuni; Schirripa, Marta; West, Jordan D; Gopez, Roel; Akihito, Tsuji; Ichikawa, Wataru; Heinemann, Volker; DePaolo, R William; Lenz, Heinz-Josef (2017). Predictive value of TLR7 polymorphism for cetuximab-based chemotherapy in patients with metastatic colorectal cancer. International journal of cancer, 141(6), pp. 1222-1230. Wiley-Blackwell 10.1002/ijc.30810
Schirripa, Marta; Zhang-Wu, Xiaxia; Heinemann, Volker; Cao, Shu; Okazaki, Satoshi; Yang, Dongyun; Loupakis, Fotios; Berger, Martin Dave; Ning, Yan; Miyamoto, Yuji; Suenaga, Mitsukuni; Gopez, Roel F; West, Jordan D; Hanna, Diana; Barzi, Afsaneh; Falcone, Alfredo; Stintzing, Sebastian; Lenz, Heinz-Josef (2017). Single nucleotide polymorphisms in the IGF-IRS pathway are associated with outcome in mCRC patients enrolled in the FIRE-3 trial. International journal of cancer, 141(2), pp. 383-392. Wiley-Blackwell 10.1002/ijc.30715
Berger, Martin Dave; Yamauchi, Shinichi; Cao, Shu; Hanna, Diana L; Sunakawa, Yu; Schirripa, Marta; Matsusaka, Satoshi; Yang, Dongyun; Groshen, Susan; Zhang, Wu; Ning, Yan; Okazaki, Satoshi; Miyamoto, Yuji; Suenaga, Mitsukuni; Lonardi, Sara; Cremolini, Chiara; Falcone, Alfredo; Heinemann, Volker; Loupakis, Fotios; Stintzing, Sebastian; ... (2017). Autophagy-related polymorphisms predict hypertension in patients with metastatic colorectal cancer treated with FOLFIRI and bevacizumab: Results from TRIBE and FIRE-3 trials. European journal of cancer, 77, pp. 13-20. Elsevier 10.1016/j.ejca.2017.02.020
