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Hoffet, Michelle Salomé; Tomov, Nikola S.; Hupp, Sabrina; Mitchell, Timothy J; Iliev, Asparouh I. (2024). Glucose and Oxygen Levels Modulate the Pore-Forming Effects of Cholesterol-Dependent Cytolysin Pneumolysin from Streptococcus pneumoniae. Toxins, 16(6) MDPI 10.3390/toxins16060232
Müller, Annelies; Lekhuleni, Cebile; Hupp, Sabrina; du Plessis, Mignon; Holivololona, Lalaina; Babiichuk, Eduard; Leib, Stephen L.; Grandgirard, Denis; Iliev, Asparouh I.; von Gottberg, Anne; Hathaway, Lucy J. (2023). Meningitis-associated pneumococcal serotype 8, ST 53, strain is hypervirulent in a rat model and has non-haemolytic pneumolysin which can be attenuated by liposomes. Frontiers in cellular and infection microbiology, 12 Frontiers 10.3389/fcimb.2022.1106063
Hupp, Sabrina; Förtsch, Christina; Graber, Franziska; Mitchell, Timothy J; Iliev, Asparouh I (2022). Pneumolysin boosts the neuroinflammatory response to Streptococcus pneumoniae through enhanced endocytosis. Nature communications, 13(1), p. 5032. Nature Publishing Group 10.1038/s41467-022-32624-2
Baronti, Dario; Tomov, Nikola; Hupp, Sabrina; Mitchell, Timothy J; Iliev, Asparouh Iliev (2022). Dendritic spine loss deep in the neocortex and dendrite distortion with diffusion disturbances occur early in experimental pneumococcal meningitis. Frontiers in neuroscience, 16(912445), p. 912445. Frontiers Research Foundation 10.3389/fnins.2022.912445
Hupp, Sabrina; Tomov, Nikola Stefanov; Bischoff, Carolin; Baronti, Dario; Iliev, Asparouh I. (2021). Easy to build cost-effective acute brain slice incubation system for parallel analysis of multiple treatment conditions. Journal of neuroscience methods, 366, p. 109405. Elsevier 10.1016/j.jneumeth.2021.109405
Hupp, Sabrina; Iliev, Asparouh I. (2020). CSF-1 receptor inhibition as a highly effective tool for depletion of microglia in mixed glial cultures. Journal of neuroscience methods, 332, p. 108537. Elsevier 10.1016/j.jneumeth.2019.108537